Pharmaceutical packages comprising polypropylene containers and ngf aqueous formulations packaged therein
Номер патента: EP4236903A1
Опубликовано: 06-09-2023
Автор(ы): Lucia Apparente, Marcello Allegretti, Marco Maria Gentile, Simone MATTIOLI
Принадлежит: Dompe Farmaceutici SpA
Опубликовано: 06-09-2023
Автор(ы): Lucia Apparente, Marcello Allegretti, Marco Maria Gentile, Simone MATTIOLI
Принадлежит: Dompe Farmaceutici SpA
Реферат: The present invention relates to a pharmaceutical package comprising a plastic container and an aqueous formulations of nerve growth factor (NGF), in which at least the surface of the container in contact with the NGF aqueous formulation is made of particular polypropylenes (PPs), characterized by certain thermal properties and crystallinity. Advantageously said containers show a NGF adhesion significantly lower than that of siliconized glass or of other polypropylenes. It is thus possible to store aqueous formulations of NGF in less severe conditions, avoiding additional coating treatments to the containers and additives while keeping the NGF titer constant.
Pharmaceutical packages comprising polypropylene containers and ngf aqueous formulations packaged therein
Номер патента: US20230390156A1. Автор: Marcello Allegretti,Marco Maria Gentile,Lucia Apparente,Simone MATTIOLI. Владелец: Dompe Farmaceutici SpA. Дата публикации: 2023-12-07.