Gene amplification and overexpression in cancer
Реферат: There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing a gene, which is amplified in many types of cancer. The amplified genes, their expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or as vaccines; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.
Biomarkers and methods for determining efficacy of anti-egfr antibodies in cancer therapy
Номер патента: EP2443252A2. Автор: Anja von HEYDEBRECK,Christopher Stroh. Владелец: Merck Patent GmBH. Дата публикации: 2012-04-25.