Full length kinase activity-conformation reporter
Номер патента: EP3519830A1
Опубликовано: 07-08-2019
Автор(ы): Eduard Stefan, Johanna Mayrhofer
Принадлежит: UNIVERSITAET INNSBRUCK
Опубликовано: 07-08-2019
Автор(ы): Eduard Stefan, Johanna Mayrhofer
Принадлежит: UNIVERSITAET INNSBRUCK
Реферат: The present invention provides a reporter for a protein fragment complementation assay characterized in that the reporter is a fused protein comprising a first fragment, a second fragment and a protein kinase sequence section, wherein the first fragment and the second fragment are derived from different sections of the same split protein, and wherein the protein kinase sequence section intervenes between the first fragment and the second fragment and wherein the kinase sequence section comprises a kinase domain sequence and one or more regulatory sequence(s). Further the invention provides polynucleotides and cells encoding for the reporter as well as methods of conducting a protein fragment complementation assay with the reporter according to the invention.
Full length kinase activity-conformation reporter
Номер патента: US20220137060A1. Автор: Eduard Stefan,Johanna MAYERHOFER. Владелец: UNIVERSITAET INNSBRUCK. Дата публикации: 2022-05-05.