Screening methods for identifying specific staphylococcus aureus inhibitors
Номер патента: EP2342339A2
Опубликовано: 13-07-2011
Автор(ы): Richard H. GUENTHER, Samuel P. Yenne
Принадлежит: Trana Discovery Inc
Опубликовано: 13-07-2011
Автор(ы): Richard H. GUENTHER, Samuel P. Yenne
Принадлежит: Trana Discovery Inc
Реферат: Methods of inhibiting S. aureus propagation, and screening for compounds that inhibit S. aureus propagation, are described. A method of inhibiting S. aureus propagation comprises inhibiting ribosomal binding of a specific S. aureus tRNA in the S. aureus by an amount sufficient to inhibit S. aureus protein expression. A method of screening for compounds useful for inhibiting S. aureus propagation comprises contacting a specific S. aureus tRNA to a ribosome that binds that tRNA in the presence of the test compound, and then determining whether the compound inhibits the binding of that tRNA.
Screening method of therapeutic and diagnostic agents for tnf-alpha-induced diseases using reactive oxygen species modulator 1
Номер патента: EP2451978A1. Автор: Jung-jin Kim,Young-Do Yoo. Владелец: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION. Дата публикации: 2012-05-16.