New diagnostic tools for charcot-marie-tooth disease
Опубликовано: 26-09-2012
Автор(ы): Daniel Cohen, Ilya Chumakov, Oxana Guerassimenko, Serguei Nabirochkin
Принадлежит: Pharnext SA
Реферат: The present invention relates in particular to methods of detecting predisposition to or diagnosis and/or prognosis of Charcot-Marie-Tooth (CMT) and related disorders. More specifically, the invention relates to development, validation and application of new biomarkers, which can be used for detecting the presence or risk of CMT disease and related disorders. In particular, the present invention relates to metabolite, lipid, carbohydrate and proteinaceous biomarkers that can be measured in biological body fluids and easily available extracts of biopsies, which can be used to aid in the detection, prediction of drug treatment and follow up of this treatment of neurodegenerative disorders, including CMT disease. The present invention also relates to methods for identification of CMT disease sub-types, assessing the responsiveness to the treatments and the efficacy of treatments in subjects having CMT or a related disorder.
Diagnostic tools for charcot-marie-tooth disease
Номер патента: US09945876B2. Автор: Daniel Cohen,Ilya Chumakov,Serguei Nabirochkin. Владелец: Pharnext SA. Дата публикации: 2018-04-17.