Diabetes treatment traditional Chinese medicine composition and preparation method and application thereof

Technical Field

The invention belongs to the field of traditional Chinese medicine, and in particular relates to a method for the treatment of diabetes composition and its preparation method and application.

Background Art

Diabetes is a group to hyperglycemia metabolic diseases characterized. Hyperglycemia is the result of the insulin secretion defect or its biological role damaged, or both causes. Diabetes long-term hyperglycemia, lead to various organizations, especially an eye, kidney, heart, blood vessel, nerve of chronic damage, dysfunction.

Diabetes in a patient blood sugar in the standard, on the other hand the lack of sugar in the cell, the required nutrient cannot enter into cells, caused by diabetes. Persons with fatigue of diabetes patients, health marasmus, easy to skin , respiratory, urinary biliary system various inflammation. The present for the treatment of diabetes, the variety of western medicine, western medicine hypoglycemic effect is obvious, but long-term administration of the side effects caused by the stomach, liver, kidney damage, and in dependence of the patient, the existing traditional Chinese medicine although toxic side effects, long-term administration dependent on, but hypoglycemic effect is not obvious and curative effect is not stable, in particular to the type II diabetes, simple of traditional Chinese medicine and western medicine treatment effect is not ideal, cannot be completely removing the cause, to achieve the purpose of complete cure.

Content of the invention

One of the purposes of the present invention is to provide a medicinal composition for treating diabetes.

The present invention for the treatment of diabetes composition, comprises the following parts by weight of the raw material: Morinda officinalis 20 parts -30 parts, schisandra chinensis 15 parts -20 parts, Poria (Indian bread) 20 parts -30 parts, yam 20 parts -40 parts, semen Cuscutae 20 parts -30 parts, rhubarb 20 parts -25 parts, white peony root 15 parts -20 parts, Rhizoma Chuanxiong 20 parts -25 parts, leech 15 parts -20 parts, kudzu root 20 parts -30 parts, radix Astragali 15 parts -25 parts, radix Scrophulariae 20 parts -30 parts, Rhizoma Atractylodis 15 parts -20 parts, winter day 25 parts -30 parts, Achyranthis Bidentatae 15 parts -20 parts, Rhizoma Alismatis (alisma rhizome) 25 parts -30 parts, radix Trichosanthis 20 parts -30 parts, Anemarrhena asphodeloides 20 parts -30 parts, root 30 parts -40 parts, polygonatum 15 parts -20 parts, cortex Lycii 25 parts -30 parts and 25 parts -30 parts.

The present invention for the treatment of diabetes composition, it has nourishing the stomach, the spleen, the liver and regulating Qi, phlegm, quench one's thirst hypoglycemic, , repairing the efficacy of the pancreas, can effectively reduce the glucose in urine, in addition, can also promote the regeneration of pancreatic islet cells, promote the secretion of endogenous insulin, adjust the metabolic balance, improving immunity, fundamentally cure various complications caused by diabetes, without side effects, while at the same time adding homology of food, at the same time treatment of health care.

In addition, this invention above-mentioned is used for the treatment of diabetes composition, can also be provided with the following additional technical characteristics:

As a preferred embodiment of the invention, the used for the treatment of diabetes composition, comprises the following parts by weight of the raw material: Morinda officinalis 20 parts, schisandra chinensis 20 parts, Poria (Indian bread) 20 parts, yam 40 parts, semen Cuscutae 20 parts, rhubarb 25 parts, white peony root 15 parts, Rhizoma Chuanxiong 25 parts, leech 15 parts, kudzu root 30 parts, radix Astragali 15 parts, radix Scrophulariae 30 parts, Rhizoma Atractylodis 15 parts, winter day 30 parts, Achyranthis Bidentatae 15 parts, Rhizoma Alismatis (alisma rhizome) 30 parts, radix Trichosanthis 20 parts, Anemarrhena asphodeloides 30 parts, root 30 parts, the brush 20 parts, cortex Lycii 25 parts and 30 parts.

As a preferred embodiment of the invention, the used for the treatment of diabetes composition, comprises the following parts by weight of the raw material: Morinda officinalis 30 parts, schisandra chinensis 15 parts, Poria (Indian bread) 30 parts, yam 20 parts, semen Cuscutae 30 parts, rhubarb 20 parts, white peony root 20 parts, Rhizoma Chuanxiong 20 parts, leech 20 parts, kudzu root 20 parts, radix Astragali 25 parts, radix Scrophulariae 20 parts, Rhizoma Atractylodis 20 parts, winter day 25 parts, Achyranthis Bidentatae 20 parts, Rhizoma Alismatis (alisma rhizome) 25 parts, radix Trichosanthis 30 parts, Anemarrhena asphodeloides 20 parts, root 40 parts, polygonatum 15 parts, cortex Lycii 30 parts and 25 parts.

As a preferred embodiment of the invention, the used for the treatment of diabetes composition, comprises the following parts by weight of the raw material: Morinda officinalis 26 parts, schisandra chinensis 17 parts, Poria (Indian bread) 25 parts, yam 30 parts, semen Cuscutae 25 parts, rhubarb 23 parts, white peony root 17 parts, Rhizoma Chuanxiong 23 parts, leech 17 parts, kudzu root 25 parts, radix Astragali 20 parts, radix Scrophulariae 25 parts, Rhizoma Atractylodis 17 parts, winter day 27 parts, Achyranthis Bidentatae 17 parts, Rhizoma Alismatis (alisma rhizome) 28 parts, radix Trichosanthis 25 parts, Anemarrhena asphodeloides 25 parts, root 35 parts, polygonatum 17 parts, cortex Lycii 27 parts and 27 parts.

The invention another object of the invention is to provide the used for the treatment of diabetes composition preparation method, comprises the following steps: first of all the raw materials are mixed and drying, and then the raw material with water in accordance with the weight ratio of 1: 1.5 after mixing, heating to boiling, then boiling 2h - 5h, re-filtering and collecting the filtrate, to obtain Chinese medicinal composition for the treatment of diabetes.

Further, in the filtering, the screen diameter of 1 μm - 20 μm.

Further, the drying, the drying temperature is 50 °C -70 °C, drying time is 30 min - 50 min.

The invention of another purpose is to provide the method for the preparation of a composition for the treatment of diabetes in the application of traditional Chinese medicine.

The invention additional aspects and advantages will be given below in the description of the part, the part will be from below in the description of becomes significant, or through the practice of the present invention to understand.

Mode of execution

The following detailed description of the embodiment of the invention, said embodiment is exemplary, intended to be used to explain the invention, but could not be construed as limited to this invention.

In the following embodiment of the experimental method, in the absence of special note, is the conventional method.

The following embodiment used in the test material, in the absence of special note, are self-conventional reagent stores the obtained.

In the following embodiment of the Morinda officinalis, schisandra chinensis, Poria (Indian bread), yam, semen Cuscutae, rhubarb, Paeoniae alba, Rhizoma Chuanxiong, leech, kudzu root, radix astragali, radix Scrophulariae, Rhizoma Atractylodis, radix Asparagi, Achyranthis Bidentatae, Rhizoma Alismatis (alisma rhizome), radix Trichosanthis, Anemarrhena asphodeloides, root, rhizome, cortex Lycii and are consistent with the Chinese Pharmacopeia (2015 and bank) a part of the text of the various medicinal materials under the relevant provisions. Feeding the front, through the identification, medicinal materials are consistent with the name of the kind, quality standard.

Embodiment 1

Embodiment 1 provides a method for the treatment of diabetes composition, comprises the following parts by weight of the raw material: Morinda officinalis 20 parts, schisandra chinensis 20 parts, Poria (Indian bread) 20 parts, yam 40 parts, semen Cuscutae 20 parts, rhubarb 25 parts, white peony root 15 parts, Rhizoma Chuanxiong 25 parts, leech 15 parts, kudzu root 30 parts, radix Astragali 15 parts, radix Scrophulariae 30 parts, Rhizoma Atractylodis 15 parts, winter day 30 parts, Achyranthis Bidentatae 15 parts, Rhizoma Alismatis (alisma rhizome) 30 parts, radix Trichosanthis 20 parts, Anemarrhena asphodeloides 30 parts, root 30 parts, polygonatum 20 parts, cortex Lycii 25 parts and 30 parts.

Embodiment 1 used for the treatment of diabetes composition preparation method, comprises the following steps: first of all the raw materials are mixed in 70 °C dried under the temperature 30 min, then the raw materials with water according to the weight ratio of 1: 1.5 after mixing, heating to boiling, then boiling 2 h, re-filtering and collecting the filtrate, to obtain Chinese medicinal composition for the treatment of diabetes. Wherein during filtration, the screen diameter of 20 μm.

Embodiment 2

Embodiment 2 provides a traditional Chinese medicine for the treatment of diabetes composition, comprises the following parts by weight of the raw material: Morinda officinalis 30 parts, schisandra chinensis 15 parts, Poria (Indian bread) 30 parts, yam 20 parts, semen Cuscutae 30 parts, rhubarb 20 parts, white peony root 20 parts, Rhizoma Chuanxiong 20 parts, leech 20 parts, kudzu root 20 parts, radix Astragali 25 parts, radix Scrophulariae 20 parts, Rhizoma Atractylodis 20 parts, winter day 25 parts, Achyranthis Bidentatae 20 parts, Rhizoma Alismatis (alisma rhizome) 25 parts, radix Trichosanthis 30 parts, Anemarrhena asphodeloides 20 parts, root 40 parts, polygonatum 15 parts, cortex Lycii 30 parts and 25 parts.

Embodiment 2 for the treatment of diabetes composition preparation method, comprises the following steps: first of all the raw materials are mixed after 50 °C dried under the temperature 50 min, then the raw materials with water according to the weight ratio of 1: 1.5 after mixing, heating to boiling, then boiling 5 h, re-filtering and collecting the filtrate, to obtain Chinese medicinal composition for the treatment of diabetes. Wherein during filtration, the screen diameter of 1 μm.

Embodiment 3

Embodiment 3 provides a traditional Chinese medicine for the treatment of diabetes composition, comprises the following parts by weight of the raw material: Morinda officinalis 26 parts, schisandra chinensis 17 parts, Poria (Indian bread) 25 parts, yam 30 parts, semen Cuscutae 25 parts, rhubarb 23 parts, white peony root 17 parts, Rhizoma Chuanxiong 23 parts, leech 17 parts, kudzu root 25 parts, radix Astragali 20 parts, radix Scrophulariae 25 parts, Rhizoma Atractylodis 17 parts, winter day 27 parts, Achyranthis Bidentatae 17 parts, Rhizoma Alismatis (alisma rhizome) 28 parts, radix Trichosanthis 25 parts, Anemarrhena asphodeloides 25 parts, root 35 parts, polygonatum 17 parts, cortex Lycii 27 parts and 27 parts.

Embodiment 3 for the treatment of diabetes composition preparation method, comprises the following steps: first of all the raw materials are mixed after 60 °C dried under the temperature 40 min, then in accordance with the raw materials with water in a weight ratio of 1: 1.5 after mixing, heating to boiling, then boiling 3.5 h, re-filtering and collecting the filtrate, to obtain Chinese medicinal composition for the treatment of diabetes. Wherein during filtration, the screen diameter of 10 μm.

Toxicity test

The selected weight for 18 - 22 parts of white mouse 300 only (the male and female all 150 only), is divided into 3 groups, each group of female all 25 only, removing the back of the MICE deburring exposed, unhairing range 2 cm × 2 cm, respectively applying the embodiment of the invention 1 to embodiment 3 prepared Chinese medicinal composition, the dosage is 0.5 parts, continuous administration of 30 days. During and after the discontinuation of the drug to 1 week, observing the mouse growth state and activities diet, identifying hematologic, blood biochemistry, and to check the structure such as a bath. Found all MICE are healthy survival, without any toxic side effect; anatomical observation hemograms, liver function, various organ tissue state, compared with the normal MICE no difference. Experiments prove that, the present invention provides a medicinal composition of toxic, safe and reliable.

From the foregoing, the present invention for the treatment of diabetes composition, it has nourishing the stomach, the spleen, the liver and regulating Qi, phlegm, quench one's thirst hypoglycemic, , repairing the efficacy of the pancreas, can effectively reduce the glucose in urine, in addition, can also promote the regeneration of pancreatic islet cells, promote the secretion of endogenous insulin, adjust the metabolic balance, improving immunity, fundamentally cure various complications caused by diabetes, without side effects, while at the same time adding homology of food, at the same time treatment of health care.

In the description of this specification, with reference to the terminology "one embodiment", "some embodiments", "an example", "specific example", or "some example" such as described imply that of this embodiment or the combination of the specific characteristics of the example described, the structure of the, material or the characteristics of the present invention comprising for at least one embodiment or example. In the specification, the above terminology the illustrative statements must not directed against the same embodiment or example. And, the specific characteristics described, structure, material or feature can in any one or more of embodiment or example in combined in an appropriate manner. In addition, in the case of mutual contradiction, the staff of the technical field can be described in the specification of the different embodiments or examples and different embodiments or examples of the characteristics of the binding and combined.

Although it has already been shown and described the embodiment of the invention, it will be understood that, the above embodiment is illustrative of the, could not be construed as limiting of the present invention, the ordinary technical personnel in the field of the present invention can be within the range of the change of the above-mentioned examples, modification, replacement and modify.