04-07-2019 дата публикации
Номер: US20190202838A1
Принадлежит:
Disclosed are a class of fused cyclic compounds against the HCMV virus, and use thereof in the preparation of a drugs for treating diseases associated with the HCMV virus. In particular, disclosed is the compound shown in formula (II) and pharmaceutically acceptable salts thereof. 4. (canceled)6. (canceled)7. The compound claim 2 , the pharmaceutically acceptable salt or the tautomer thereof as defined in claim 2 , wherein claim 2 , Ris H claim 2 , F claim 2 , Cl claim 2 , Br or I claim 2 , or selected from the group consisting of Calkyl claim 2 , (Calkyl)-O— and (Calkyl)-S— claim 2 , each of which is optionally substituted by 1 claim 2 , 2 or 3 R;{'sub': '1', 'or, Ris H, F, Cl, Br or I, or selected from the group consisting of Me and Et, each of which is optionally substituted by 1, 2 or 3 R;'}{'sub': '1', 'or, Ris H, F, Cl, Br, I, Me or Et.'}8. (canceled)9. (canceled)11. (canceled)12. (canceled)14. (canceled)15. (canceled)16. The compound claim 2 , the pharmaceutically acceptable salt or the tautomer thereof as defined in claim 2 , wherein claim 2 , T is N claim 2 , CH claim 2 , C(F) claim 2 , C(Cl) claim 2 , C(Br) or C(I).18. (canceled)19. (canceled)22. (canceled)24. (canceled)25. The compound claim 1 , the pharmaceutically acceptable salt or the tautomer thereof as defined in claim 1 , wherein claim 1 , Ris H claim 1 , F claim 1 , Cl claim 1 , Br or I claim 1 , or selected from the group consisting of Calkyl claim 1 , (Calkyl)-O— and (Calkyl)-S— claim 1 , each of which is optionally substituted by 1 claim 1 , 2 or 3 R;{'sub': '1', 'or, Ris H, F, Cl, Br or I, or selected from the group consisting of Me and Et, each of which is optionally substituted by 1, 2 or 3 R;'}{'sub': '1', 'or, Ris H, F, Cl, Br, I, Me or Et.'}26. (canceled)27. (canceled)29. (canceled)30. (canceled)32. (canceled)33. (canceled)34. The compound claim 1 , the pharmaceutically acceptable salt or the tautomer thereof as defined in claim 1 , wherein claim 1 , T is N claim 1 , CH claim 1 , C(F) ...
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