INTERNALLY GENERATED CLOSE CAPTIONING/TELE-TEXTING FOR SET-UP MENUS OF NETWORK-CAPABLE SIGNAL PROCESSING APPARATUS

Implicit information card

Implicit information card has a information layer comprising several information blocks fixed onto a substrate and the information layer and the substrate have obvious difference in reflectivity. A shielding layer covers the substrate part and the information chips in information area completely and there are also magnetic anti-fake uholes embedded inside the substrate. The present invention hasthe advantages of powerful anti-fake capacity, high wear resistance and stable performance. Furthermore, the substrate may be manufactured into non-directional one for convenient use.

Design method and system of protocol simulation system facing service

To solve the problems of poor flexibility, serious resource waste, strong coupling, etc. of the prior protocol simulation technique in the communication field, the invention provides a protocol simulation system designing method facing to services and a system thereof. In the protocol simulation technique designing method facing to services of the invention, a service module and a main control module are separately designed and positioned; a communication source language for communication is adopted between the main control module and the service module in order that an normal operation of a protocol simulation system is not influenced when the service requirement of the user is changed or a main control system is upgraded; only the service module is needed to increase. The protocol simulation system designed by the protocol simulation system designing method facing to services can further make use of various resources and has strong flexibility.

Structure for connecting pouring cup with pouring gate pipe

Abstract The invention relates to a structure for connecting a pouring cup with a pouring gate pipe, which belongs to the technical field of manufacturing of sand mold casts. The connection structure can effectively prevent molten metal from jacking up the pouring cup and further prevent the overflow of the molten metal, thereby not only improving the production efficiency, but also effectively avoiding accidents during the casting process. The structure for connecting the pouring cup with the pouring gate pipe comprises the pouring cup and the pouring gate pipe, wherein the pouring cup comprises a tapered molten metal flow passage which is big at the upper end and small at the lower end, a slot which is coaxial with the molten metal flow passage is formed at the lower end of the pouring cup, the inner diameter of the slot is matched with the outer diameter of the pouring gate pipe, and the upper end of the pouring gate pipe is inserted and matched in the slot.

Fixed element light splitter for co-shaping x-ray fluorescence spectrometer

The invention discloses a kind of fixed element track light splitter used in the fluorescent X-ray spectrometer which includes the entrance slit pipe module, the light splitting box module connected with the tail of entrance slit pipe and the exit slit pipe module connected with the splitting box module. Compared to the normal fixed element track light splitter, there have two curved crystal diffraction light path. So in the same out side of splitter, the invention can detect the element kinds from one to two by each splitter but not increase the diameter of vacuum detection room and the splitter number to make the detection element kinds fold increase and enlarge the instrument application field. The other side, in the definite detection element kinds, the invention can decrease the splitter number and the vacuum detection room diameter to simplify the apparatus and decrease the cost.

Method and system for analyzing article coding

The invention discloses an article code analytic method and an article code analytic system. The method comprises the following steps: a first layer of slave server acquires an article code carried by a code analysis request according to the received code analysis request; judgment is made whether to analyze the article code in the first slave server according to a code system identifier of the article code; and if so, the first slave server analyzes the article code and returns analysis result information, or else the first slave server transmits the code analysis request to a primary server. The system comprises the first slave server and the primary server. The first slave server and the primary server of the system can simultaneously complete the function of unified monitoring and management of article codes and can achieve the effect of sharing the article codes in the first slave server and the primary server, thereby meeting the technical demand of whole-network analysis of thearticle ...

Adapting software components by changing part of the component based on a context oriented adaptation specification and an adaptation rule.

Disclosed is a method of adapting software components by extracting the component specification of binary code and metadata from the component, creating a context oriented adaptation specification and adapting at least part of the component based on the adaptation specification and an adaptation rule. An adapted component is then generated using the adapted and un-adapted parts of the software. The adaptation rule may be generated or chosen from a list. The adaptation rule may be automatically triggered when a particular adaptation is required, with the resultant adaptation algorithm producing one or more adaptations. The component may be selected according to a pre-qualification process based on system requirements. The adaptation rules may be created using programming knowledge on component based systems (CBS) and components or from application domain knowledge. The method may include a step of checking against a healthiness condition and warning the user if the conditions are not met ...

Chromatographic material and methods for the synthesis thereof

A particulate material for chromatographic use comprising silica particles is provided having a skeleton structure containing silsesquioxane cage moieties. The material is useful as a chromatographic material, for example in HPLC. The silica particles may be hybrid organo-silica particles wherein the silsesquioxane moieties comprise a cage structure having silicon atoms positioned at corners of the cage wherein one or more silicon atoms positioned at the corners of the cagecarry an organic group. A preferred method of preparing the particulate material comprises hydrolysing a silsesquioxane as a co-component of a hydrolysis mixture, especially ina Stober or modified Stober process.

Compositions and methods for modulating c-kit and PDGFR receptors

Coaxial connector's female head and coaxial connector

Coaxial connector's female head and coaxial connector. Female head is including female first outer conductor connecting portion and female first inner conductor connecting portion. When public head linked to each other with female head, female first outer conductor connecting portion were connected with public first outer conductor connecting portion electricity to public first inner conductor connecting portion are connected with female first inner conductor connecting portion electricity. Female first outer conductor connecting portion include drum portion and are located the annular wall of the first end department of drum portion, the annular wall extends along radial outside direction, and extend with the second end that the first end is relative towards the drum is the portion, when public head links to each other with female head, the internal surface of the public first outer conductor connecting portion of annular wall butt, thereby it connects to realize the electricity between ...

Large-volume coke oven coking chamber temperature sensor

The invention provides a temperature sensor for temperature measurement of a large-volume coke oven coking chamber, which comprises a sensor element, an upper protection pipe, a lower protection pipe, a wiring box and a flange, wherein the lower protection pipe comprises three layers of high-temperature resistance sleeves at the inner side, the middle side and the outer side, the outer layer sleeve and the middle layer sleeve are both metal sleeves, the inner layer sleeve is a ceramic sleeve, the sensor element is arranged in the inner layer sleeve, asbestos is wound outside the inner layer sleeve and then schamotte is coated, wherein the head of the middle layer sleeve is not wound with the asbestos or coated with the schamotte, the inner layer sleeve integrally penetrates into the middle layer sleeve and is sealed and fixed by the schamotte, and a plurality of small holes are arranged on the head of the middle layer sleeve. The outer layer sleeve and the middle layer sleeve adopt clamp ...

Mechanical ICE cooling fan clutch

Anti-reverse square loose piece

Abstract The invention provides an anti-reverse square loose piece which comprises a loose piece body, and the loose piece body is provided with a wedge angle. The anti-reverse square loose piece can prevent reverse placement to avoid producing scrap products and saves the production cost. 9)B ...

Compounds and compositions as protein kinase inhibitors

Real-time image scaling engine suitable for various 4*4 interpolation filters

The invention discloses a real-time image scaling engine suitable for various 4*4 interpolation filters. A line memory adopted in the invention is an SRAM with a bit width of 24 bits, and each line can store 2560 pixels at most. In the invention, only five lines of image data need to be stored to support image scaling with a maximum resolution of 2560*1960, so that the requirement of real-time scaling can be met and more hardware resources can be saved compared with hardwares of the same type. A source clock control module operates at the source clock frequency, a target clock control module operates at the target clock frequency and the source clock control module and the target clock control module realize trans-clock domain operation by controlling reading and writing of line memory data. In the invention, when image amplification operation and image reduction operation are carried out, in response to different realization of the hardware, multiple multi-path selectors are adopted to ...

Chromatographic material having improved PH stability, method for preparation thereof and uses thereof

A chromatographic material including a substrate having a surface and having a polymeric layer covalently bound to the surface; the polymeric layer comprising polymer molecules covalently attached to the surface of the substrate, each polymer molecule being attached to the surface via multiple siloxane bonds and each polymer molecule being connected to one or more functionalizing compounds that each comprise a functional group, wherein the polymeric layer is formed by covalently attaching polymer molecules to the surface of the substrate via multiple siloxane bonds, each polymer molecule containing multiple first reactive groups, and reacting the first reactive groups of the attached polymer molecules with at least one functionalizing compound that comprises a second reactive group that is reactive with the first reactive groups and that further comprises a functional group. Preferred conditions of reacting the polymer with the substrate include elevated temperature and reduced pressure ...

Casting with pad

Abstract The invention provides a casting with pad, which comprises a casting body and a pad arranged on the casting body, and the distance between the lateral pan of the pad and the edge of the casting body is 10-15mm. The casting with pad can ensure the position for gas cutting can be easily found when the pad is removed by gas cutting, the casting body can not be damaged, and the pad can be easily cut off. FIG. 1 FIG. 2 FIG. 4 FIG. 5 ...

Compounds and compositions as protein kinase inhibitors

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to beat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of c-kit, PDGFR and PDGFR kinases. Formula (I).

Tooth thread box

The invention relates to a dentary appliance for cleaning oral cavity, specifically to a dental floss box which is provided with a box and a cover. The box is provided with grooves. A dental floss educing hole and cutting knife is arranged in the groove. Dental floss slot provided with dental floss loop is arranged in the box. With the configuration; the invention has the advantages of reduced thickness, simple structure, low cost, large capacity, and convenient carry.

Method and device for processing forwarding table

The invention discloses a method and a device for processing a forwarding table. The method comprises the following steps that: when a first routing table entry in a routing table is processed, network equipment judges whether a second routing table entry capable of aggregating the first routing table entry exists in the forwarding table or not; and if the second routing table entry exists and a next hop address of the first routing table entry is the same as that of the second routing table entry, the first routing entry is forbidden to be added into the forwarding table. The method and the device can simply and fast determine the routing table entry not to be added to the forwarding table and effectively avoid adding an unnecessary routing table entry into the forwarding table by judging whether the table entry exists in the forwarding table or not and the next hop address of the table entry so as to reduce the capacity of the forwarding table on the premise of ensuring the normal communication ...

Measurement method for positive sequence parameter of high-voltage transmission line

The present invention relates to a positive sequence parameter measurement method of the ultrahigh-tension power transmission line. The measurement method adopts the single-phase testing power supply to exert the positive phase voltage and the reversed phase voltage on the line to be detected, utilizes the measured values of the voltage, the current and the power before and after the reversed phase, combines the measured interference voltage before the voltage is exerted on the line, eliminates the influence of the interference voltage through calculation, and then acquires the phase to phase impedance; and the phase to phase impedances of the other two phases are respectively measured, and the positive sequence parameters of the high voltage transmission line are acquired through calculation. The invention has the advantages that in the environment of strong electromagnetic interference, in particular under the condition that the three phases have different interference voltages, the positive ...

Leakproof casting box

The invention provides a leakproof casting box, comprising an upper box and a lower box, wherein the joint face of the upper box is provided with a boss, and the joint face of the lower box is provided with a groove corresponding to the boss. The casting box provided by the invention can prevent seepage of molten steel in the box, thus steel leakage is avoided.

Chromatographic material having improved PH stability, method for preparation thereof and uses thereof

Protecting structure for foundry type of sand mold cast

Abstract The invention relates to a protecting structure for a foundry type of a sand mold cast, which belongs to the technical field of processing and manufacturing of sand mold casts. The protecting structure comprises a cast body, the foundry type which is integrated with the cast body into a whole is ranged on the cast body, the cast body is correspondingly provided with a bulge which is higher than the foundry type beside the foundry type, and the bulge and the cast body are integrally molded. The protecting stucture can effectively avoid damaging the foundry type of the sand mold cast during the shakeout process, further reduce the working time for repair welding and polishing, improve the production efficiency, reduce the waste of raw materials and solve the problems that the foundry type in the prior art is easy for being damaged due to collision during the shakeout process and thus increases the working time for repair welding and polishing in post-treatment and causes the low ...

Building formwork net making method and equipment

The present invention discloses a building form net making method and apparatus. There are several net fixing frames moving along upper and lower ring tracks, and two assembling presses arranged in the production line to complete main assembling job. In other working sites arranged along the ring production line, the rest parts are assembled. In the production line, both common form net and heat sulating form net may be assembled.

Fixed element light splitter for co-shaping x-ray fluorescence spectrometer

The invention discloses a kind of fixed element track light splitter used in the fluorescent X-ray spectrometer which includes the entrance slit pipe module, the light splitting box module connected with the tail of entrance slit pipe and the exit slit pipe module connected with the splitting box module. Compared to the normal fixed element track light splitter, there have two curved crystal diffraction light path. So in the same out side of splitter, the invention can detect the element kinds from one to two by each splitter but not increase the diameter of vacuum detection room and the splitter number to make the detection element kinds fold increase and enlarge the instrument application field. The other side, in the definite detection element kinds, the invention can decrease the splitter number and the vacuum detection room diameter to simplify the apparatus and decrease the cost.

Dual-mode control method and system for stepping motor

The invention is a step motor double-mode control method and system, and the method includes a open-loop step mode that a mode switcher directly feeds a step pulse signal from a computer to a driver and a DC brushless closed-loop speed servo mode that the mode switcher receives a grating signal as a step pulse to feed the grating signal to the driver and simultaneously the grating signal also acts as a speed feedback signal to compare with a given speed signal, their difference value drives a voltage servo regulator to give a proper control voltage and it maintains a constant starting difference value between the driving pulse sent from the step driver and the obtained driving pulse. And the system includes a load driven by step motor, a grating sensor connected with the other end of the load, a controller connected with the grating sensor, a control computer connected with the controller and a step driver that drives the step motor.

Heat radiating plate and manufacture method thereof

The invention relates to a heat radiating plate and a manufacture method thereof. The heat radiating plate comprises a base (1) and a top cover (2), wherein the base (1) is buckled with the top cover (2); a sealing cavity is formed between the base (1) and the top cover (2); and an injection and exhaust pipe (4) is inserted on the side wall of the top cover (2). The heat radiating plate is characterized in that the sealing cavity is internally provided with a supporting member (3) supported between the base (1) and the top cover (2); and the upper surface of the base (1) and the lower surface of the top cover (2) are respectively provided with a sintering copper powder layer (5). In the invention, because the sealing cavity formed between the base and the top cover is internally provided with the supporting member, the problem that copper materials become soft after high-temperature sintering and silver soldering and the problem that a plate is inwards sunk and deformed due to negative ...

COMPUESTOS Y COMPOSICIONES COMO INHIBIDORES DE LA QUINASA C-KIT

Son útiles como inhibidores de la proteína quinasa, así como también métodos para utilizar estos compuestos para tratar, aliviar o prevenir un trastorno asociado con la actividad anormal o desregulada de la quinasa. En algunas realizaciones, la presente proporciona métodos para utilizar estos compuestos para tratar, aliviar o prevenir enfermedades o trastornos que implican la activación anormal de c-kit o quinasas c-kit y PDGFR (PDGFRa, PDGFRb). Reivindicación 1: Un compuesto de la fórmula (1) ó la fórmula (2), ó una sal farmacéuticamente aceptable del mismo, en donde: m es 1 y R²⁰ se selecciona a partir de H, halo, alquilo C₁₋₆, haloalquilo C₁₋₆, haloalcoxilo C₁₋₆, deuterio, alquilo C₁₋₆ deuterado, -CN, -(CR⁹₂)ₙOR⁴, -C(O)R⁴, -(CR⁹₂)ₙC(=O)OR⁴, R¹⁰, -(CR⁹₂)ₙR¹⁰, -((CR⁹₂)ₙO)ₜR⁴, -(CR⁹₂)ₙO(CR⁹₂)ₙR⁷, -(CR⁹₂)ₙC(=O)R⁴, -C(=O)N(R⁴)₂, -OR⁴, y -(CR⁹₂)ₙCN; ó m es 4 y R²⁰ es deuterio; R¹ se selecciona a partir de alquilo C₁₋₆ y halo; cada R¹¹ se selecciona independientemente a partir de H, halo y ...

Chromatographic materail and method for preparation thereof

A chromatographic materialcomprisinga zwitterionic ligand covalently bound to a substrate, the ligand preferably has a formula II: wherein R1, R2, R3 are independently selected from an oxygen atom that is configured to connect to a substrate atom in the substrate, an oxygen atom that is configured to connect to a silicon atom of an adjacent ligand, a hydroxyl group, a halogen atom, an alkoxy group, a dialkylamino group, an acyl group, an alkyl group, or an aryl group; L1, L2 and L3 are independently hydrophobic moieties; each containing 2 to 30 carbon atoms, wherein there are at least 10 carbon atoms in the combined chain lengths of L1, L2 and L3; X is an O atom, S atom, amide group or sulfonamide group; n is 0 or 1; R4, R5 are independently selected from a hydrogen atom or a hydrocarbon moiety containing 1 to 20 carbon atoms; and Rf is a negatively charged moiety comprising a sulfonic, carboxylic, or phosphonic functional group.

Chromatographic material and methods for the synthesis thereof

5- (4- (haloalkoxy) phenyl) pyrimidine-2-amine compounds and compositions as kinase inhibitors

Coke oven body temperature measurement hole setting method with strong anti-interference performance

The invention relates to a coke oven body temperature measurement hole setting method with strong anti-interference performance, and belongs to the field of coke ovens. The method is characterized in that: temperature measurement holes are formed in a coke oven chute zone. The temperature measurement holes are cylindrical blind holes along the direction of a coke oven cross wall, the section diameter of the blind holes is 20 to 100mm, and the length of the blind holes is 1,000 to 5,000mm. The temperature measurement holes are symmetrically formed on a machine side and a coke side of a coke oven, or are independently formed on single sides of the coke oven such as the machine side or the coke side of the coke oven. Compared with the prior art, the method has the advantages that: the temperature of the bottom of a carbonization chamber of an oven body is measured, so the problem that the measurement of gas temperature is easily affected by factors such as exchange, air pressure, atmospheric ...

Internally generated close captioning/tele-texting for set-up menus of network-capable signal-processing apparatus

Method and device for tracking dense depth images

The invention discloses a method and a device for tracking dense depth images, and belongs to the field of stereo videos. The method comprises the following steps: acquiring two adjacent frame images, namely a pth frame image of which depth image is known and a qth frame image; for any pixel point (i, j) of the qth frame image, according to the color difference between the pixel point (i, j) and a pixel point (m, n) of the pth frame image and the preset two-dimensional normal distribution standard difference, acquiring the weight of the pixel point (m, n) by calculating, wherein the value range of the (m, n) uses the (i, j) as a center, and a preset tracking value is in a tracking window of a square side; and according to the weight of the pixel point (m, n), weighing and averaging the depths of all pixel points (m, n) in the tracking window to acquire the depth of the pixel point (i, j). The device comprises an image acquisition module, a weight calculating module and a depth tracking ...

Method for realizing multiple path optical scanning using single mode optical fiber

The method of realizing multipath light scanning with single-mode fiber includes setting closely arranged linear fiber array obliquely and setting the object plane in proper position behind the window to makes it possible to closely contact light spots via adapting circuit. The circuit part includes monostable delay counter A, trigger D, bit frequency divider U3, first-in-first-out asynchronous read/write queue memory FIFO, etc. The key point of the present invention is to utilize the characteristic that the outgoing light beam of single-mode fiber in the object plane has expanded diameter but complete edge to realize the close contact of light spots and the uniformity of different light spot modes and to reach light spot array quality much higher than that of multi-mode fiber.

Method and device for preventing sensitive information from being stolen in network

The invention provides a new method for preventing sensitive information from being stolen in a network, so as to solve the problem that the sensitive information in the network is easy to be stolen. The method comprises the steps of storing authentication information pre-stored by a customer at a server end, using the server end to respond to a client to send a request of asking for the authentication information, checking the request, generating an input sensitive information web page together with the server end and feeding back to a browser of the client, wherein, the input sensitive information web page contains a security control, and the corresponding authentication information is displayed in the security control. The method can ensure that a transactor to input the sensitive information on a real web page and effectively avoid the problem that the sensitive information is stolen.

Rotor punching plate of variable-frequency motor

The invention relates to a rotor punching plate of a variable-frequency motor, in particular to be used for a 6-pole variable-frequency motor rotor iron core with the central height of 225mm; the rotor punching plate comprises a rotor punching plate body; the punching plate is characterized in that the rotor punching plate body is provided with 64 troughs; the rotor punching plate body and an aluminium are die-cast into a whole to form a cast aluminum rotor. The amount of the matching troughs arranged on the stator punching plate body and the rotor punching plate body of the motor are changed to 54 and 64 respectively, namely, the amount of the stator punching troughs are kept unchangeable and the trough shape of the rotor punching plate is also kept unchangeable, and only the amount of the trough shapes of the rotor punching plates is changed to 64; when in use, the electromagnetic sound of the variable-frequency motor at the frequency section of 175-200Hz can be eliminated, and the whole ...

Electromotor anti-theft fastening bolt and tooth type spanner

Pressure-reducing backflow preventer

The invention discloses a pressure-reducing backflow preventer, comprising a valve body and a secondary check valve arranged in the valve body, wherein a membrane device with a primary check valve is positioned above the secondary check valve in the valve body; the lower end of the primary check valve is communicated with the upper end of the secondary check valve; a water inlet communicated with the upper end of the primary check valve is arranged on the upper part of the valve body; the lower part of the valve body is provided with a water outlet communicated with the secondary check valve; the side part of the valve body is provided with an overflow hole; and the membrane device is located in the valve body, and slides up and down in the valve body through the pressure difference between the upper and lower ends of the membrane device so as to change the connection and disconnection of the overflow hole. The pressure-reducing backflow preventer has the characteristics of reasonable structure ...

Wireless sensor network perpendicular intersection positioning algorithm

A perpendicularly-crossed positioning algorithm of a wireless sensor network is used in a wireless sensor network of limited power and random distribution. The algorithm is on the premise of a mobile beacon with known self position, wherein the mobile beacon keeps broadcasting signal and current self position on a movement path line; a node records a point of highest signal intensity through comparing signal intensity, and calculates the position of the node by a geometry method according to the two points of highest signal intensity obtained from every two adjacent sides. The perpendicularly-crossed positioning algorithm requests that the path lines of the mobile beacon are two sides of an equilateral triangle and that the side length of the triangle is equal to the transmission radius R of the mobile beacon. The algorithm can accurately calculate the position of the node through using just one mobile beacon, thereby improving system extensibility and usability and reducing hardware requirement ...

Flenibility fibre crack-resistance mastic and its preparation process

An anti-cracking flexible fibrous putty is proportionally prepared from the elastic emulsion made up of butyl acrylate, styrene, isobutyl acrylate, acrylic acid and dwater, flexible fibres with 4-6 mm in length, assistant and water through proportional mixing, stirring while reaction, adding filler, and stirring. Its advantages are high anticracking and impervious performance, flexibility and flowability, and moderate adhesion.

Composite vitamin pre-mixed feed produced by grouping pre-mixed method and preparation

The invention relates to a vitamin compound pre-mixed feed which is produced by grouping and pre-mixing and a prepration method thereof. The grouping is mainly based on the differences on the physical and the chemical properties of the components of the vitamin compound pre-mixed feed, the vitamin monomers with the same physical and the chemical properties are arranged in a group, the pre-mixing is carried out, and the semi-finished product after the mixing is prepared and mixed according to the proportion to prepare the vitamin compound pre-mixed feed. The grouping and the pre-mixing methods are as follows: the divided groups are the oxidative vitamin monomer pre-mixing group, the reductive vitamin monomer pre-mixing group, non-oxidative or reductive vitamin monomer pre-mixing group, the acidic vitamin monomer pre-mixing group, the alkaline vitamin monomer pre-mixing group and the neutral vitamin monomer pre-mixing group. The vitamin compound pre-mixed feed prepared by the invention has ...

Fume heating furnace with fume and medium counter flow

Method and apparatus for backing up application code upon power failure during acode update

Polar silanes and their use on silica supports

Polar silanes for binding to substrates and use of the bound substrates in chromatography

New organosilanes and substrates covalently bonded with same and methods for synthesis and use

Compounds and compositions as c-kit and PDGFR kinase inhibitors

Heat treatment of sulfuric acid resistant stainless steel

A heat treatment technology for stainless steel resisting againt sulfuric acid includes such technological steps as solid dissolving treating at 1050-1150 deg.C for 1-2 hr, cooling in water, and deposition hardening at 845-855 deg.C for 2-4 hr. The stainless steel contains such components (wt.%) as C (less than 0.05), Cr (9-19), Ni (15-20), Mo (0.5-3), Cu (0.5-3), Si (6.5-8.5), N (0.1-0.3), Mn (less than 1.00), Re (0.1-0.2) and Fe (rest). The treated stainless steel has excellent antiwear and anticorrosion performance.

Medicinal liquor for treating rheumatism and its preparation

The medicine liquor is prepared with Zhuifengcao, Homalomena occula and Geranium Wilfordii as medicinal ingredients, which are dried in the shade, screened, crushed, sieved, mixed and soaked in corn liquor at 15-25 deg.c for 15-25 days with the soaked liquor being then filtered. It is used mainly to treat arthralgia, periathritis of shoulder joint, ischias, numbness of limbs, rheumatic heart disease, etc. caused by rheumatism, and has high curative effect and no toxic side effect.

Method and device for continuously dynamic crystallization production of calcium lactate

The invention provides a method for continuously dynamic crystallization production of calcium lactate and a device for implementing the method. The method comprises steps as follows: filtering and concentrating calcium lactate feed liquor generated via fermentation, and keeping weight concentration of the filtered and concentrated calcium lactate feed liquor within 20%-60%; cooling the filtered and concentrated calcium lactate feed liquor to a temperature ranging from 50 DEG C to 70 DEG C, and stirring the cooled calcium lactate feed liquor after being pumped into a transfer tank; further cooling the calcium lactate feed liquor to a temperature ranging from 20 DEG C to 50 DEG C, and stirring the cooled calcium lactate feed liquor after being pumped into a crystallizer to generate crystal mush; cooling the crystal mush in the crystallizer to a temperature ranging from 5 DEG C to 30 DEG C, and stirring the cooled crystal mush after being pumped into a recrystallizing tank and growing crystal ...

Color membrane substrate and production method thereof as well as LCD device

Full-automatic ballastless track plate fine adjustor

The invention discloses a full-automatic ballastless track plate fine adjustor, comprising a support frame and a moveable frame; the support frame are connected with each other by a six-degree-of-freedom platform system; the lower part of the support frame is provided with a supporting device and a travelling mechanism; the lower part of the moveable frame is provided with a grabbing mechanism; two sides of the support frame are respectively provided with a lateral limit wheel mechanism. After the grabbing mechanism grabs a track plate, the fine adjustor automatically adjusts the track plate through the six-degree-of-freedom platform system, and supporting and travelling of the fine adjustor are realized respectively by the supporting device and the travelling mechanism arranged at the lower part of the support frame. The fine adjustor has low labor intensity, fast adjusting speed, high adjusting accuracy, and few operation stuff, and is easy to realize full automatic adjustment.

Heterocyclic compounds and compositions as C-KIT and PDGFR kinase inhibitors

The invention provides a novel class of compounds of Formula (I), pharmaceutical compositions comprising such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of c-kit, PDGFRa and PDGFRss kinases.

COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS

2-heteroarylamino-pyrimidine derivatives as kinase inhibitors

Process for manufacturing ten-thousand-ton grade special multipurpose vessel

The invention discloses a manufacture process for a 10,000-ton class special multipurpose vessel, which is characterized by comprising the following steps: a. section construction and preparation for parts of the vessel are carried out in a section field, and all double-deck support devices are prearranged in a cargo tank of the vessel; b. section spray coating is carried out in a spray coating field; c. a hull is assembled on a slipway; d. the hull is launched; and e. a vessel test and acceptance check are performed on an outfitting quay. The production process for the 10,000-ton class special multipurpose vessel adopt the way that the cargo tank is provided with the double-deck support devices, which ensures the integrity of paint of the vessel and shortens the construction cycle of thevessel; and the prearrangement of the double-deck support devices is carried out on a horizontal plane and avoids operation in a cabin, thereby greatly improving working environment and guaranteeing the ...

POLAR SILANES FOR BINDING TO SUBSTRATES AND USE OF THE BOUND SUBSTRATES IN CHROMATOGRAPHY

Polyfunctional silicon compounds having one of the following structures: wherein at least one of R,R and Ris a leaving group which, after leaving, permits the Si in one of said structures to form a Si-O-Si or Si-O-Zr bond, wherein L, L and L comprise alkyl or substituted alkyl chains from 1 to 100 in length, wherein m = 1-100; wherein N - PG, N - PG and N - PG are nitrogen- containing polar groups; wherein each of E, E, and E comprise alkyl, substituted alkyl, aryl, or substituted aryl groups, comprising 1-50 carbon atoms, and exclude functional groups selected from the group consisting of hydroxyl, carboxyl, amino, thio, halo and sulfonate moieties. Also, such compounds bound to substrates for use as chromatography.packing.1231231212 © KIPO & WIPO 2007 ...

Wooden mold with iron chills

Abstract The invention provides a wooden mold with iron chills, which comprises a wooden mold main body and a plurality of iron chills corresponding to the wooden mold main body, and a magnet layer corresponding to the iron chills is arranged in the wooden mold main body. The wooden mold can place the iron chills in any positions of the wooden mold, thereby avoiding forgetting to place the iron chills, being convenient for operation and further upgrading the quality of a cast.

Implicit information card

Large-sized optical flat interferometry device and method

The invention discloses a device and method of interferometry for a large-scale optical plane. Wherein, the interferometry device comprises an adjustment platform for the two-axis linear motion of an interferometer, a two-dimensional tilt adjustment platform for the measured plane mirror located at the front of the adjustment platform, a laser wave-front interferometer installed in the adjustmentplatform for the two-axis linear motion of an interferometer and a control computer contained the program of measured data processing algorithm, which is connected to the laser wave-front interferometer. With the device, a plurality of obtained error surface maps of partial region can be spliced to an error surface map containing medium-high frequency (MHF) band on the whole caliber according to the measured data processing algorithm through the control computer, which includes a method for determining the initial position, an algorithm for extracting data from the overlap region and an algorithm ...

Technology for secondary recovery of gold from flotation tailings

The invention particularly discloses a technology for the secondary recovery of gold from flotation tailings, which comprises the following steps: conducting cyclone classification on ore pulp of the flotation tailings, grinding the cyclone-classified grit as crude ore, conducting ore pulp mixing on the ground ore powder, conducting cyanide leaching of gold, absorbing the leached gold by active carbon, desorbing gold-loaded carbon after saturated adsorption, and electrolyzing the desorption solution after desorption, thus obtaining gold powder. Unlike conventional processes, the technology only needs investment on the power cost of equipment and material cost instead of implementing pit discharging and pit loading by staff and vehicles, therefore, compared with the conventional treatment method, the technology has the characteristics of low cost, large treatment quantity, continuous operation and the capability of enhancing the ore dressing recovery rate by floatation technology to the ...

START-UP STRATEGY FOR HYBRID POWERTRAIN

A method to monitor program flow for multitasking real-time embedded software with ASIL rating

A method to monitor program flow of runnable processes or tasks in a multitasking real time system, the processes or tasks having different or mixed automotive safety integrity level (ASIL) ratings. Temporal and spatial freedom from interference is maintained. The method creates one or more safety goals 301-303 having different ASIL ratings on a single core processer. A plurality of runnable processes RX_Y_Zms_N are created per safety goal and memory is split and allocated such that runnable processes with the same ASIL share the same memory part. Runnable processes are allocated to tasks T1-T8 and each task is allocated a fixed time period Zms for repetition. Task are prioritized and a calling order of tasks is determined. A question generated by a monitoring module is sent to a task to detect abnormalities in runnable/task execution. A unique signature is assigned per question at the receiving task and the signature is updated as each runnable/task is executed. A final signature is derived ...

Output-image geometric-error correction method based on laser photoplotters

The invention relates to an output-image geometric-error correction method based on laser photoplotters. The method is characterized in that an original two-dimensional image array is input into an image-error correction module; grating image data is subjected to invalid-data extension and data-position exchange by correcting inclined close-packing errors, horizontal baseline angular errors or arbitrary horizontal straightness errors so as to correct geometric errors; and the corrected image data is output to an image-data output unit. An image acquiring-processing circuit adopts a method of automatically exposing and reading pixel regions so as to greatly raise the update rate of systems, raise the processing speed of the systems and provide guarantee for forecasting regions and image correlation algorithm adopted by the invention; the resolution of position correction reaches 1/N of optical fiber diameter; and the number of efficient points within row length is kept the same. As the method ...

farnesoid X receptors, their use, pharmaceutical composition, and

Heterocyclic compounds and compositions as c-kit and PDGFR kinase inhibitors

Auxiliary mould stripping device

The invention provides an auxiliary mould stripping device, comprising a riser and a riser patch. The riser is arranged on a mould flange, the riser patch is connected with the riser and arranged on the flange face of a mould, and the end face of the riser patch is provided with a mould stripping bar. The invention can effectively prevent the damage to the mould in the mould stripping process, has simple operation and higher production efficiency.

Method and apparatus for extracting edge of target

The invention discloses a method and a device for extracting target edges, and belongs to the field of computer image processing. The method comprises the following steps: receiving the initial anchor point and the terminal anchor point input on target edges of an input image; converting the input image into an edge image; and extracting target edges between the initial anchor point and the terminal anchor point according to the edge image and the preset heuristic evaluation function extraction algorithm. The device comprises a receiving module, a conversion module and an extraction module. The invention which calculates the trace between the two anchor points input on target edges by applying the heuristic evaluation function extraction algorithm has the advantage that the trace of target edges can be obtained exactly, thereby improving the accuracy of the extraction of target edges; and the invention can further obtain the trace of the target edges under the circumstance that the distance ...

Periodic time dynamic magnetized light-magnetic-synchro magneto-optic test method

A cyclic dynamic magnetizing optomagnetic synchronous magnetic light testing method synchronously imposes a linear polarization cyclic laser narrow pulse train and a cyclic alternating magnetic fieldto a magnetic sample. The cyclic alternating magnetic field realizes cyclic and dynamic magnetization of the magnetic sample. After the cyclic laser narrow pulse train reacts with the magnetic sample,polarization of transparent lights or reflected lights of the pulse train will change to measure magnetization variation of the magnetic sample. In addition, the cyclic laser pulse train synchronously triggers a time delayer to output a time delay of the same frequency and time to adjust a synchronous trigger cyclic alternating magnetic field with adjustable electric pulse train. Thus, the laserpulse reacting with the sample repeatedly measures a same magnetization stable in the cyclic alternating magnetization of the sample and converts the measuring in the dynamic magnetization into staticmeasuring ...

Design method and system in protocol message editing system

To solve the problems of the communication protocol simulation system of the prior art that the support protocol is single, the protocol information which can be edited by a user is only limited to the modification of some values of the information property and that an editing screen does not express the correlation between the protocol information, the invention provides a method for designing aprotocol information editing system and a system. The method for designing a protocol information editing system of the invention establishes a template library consisting of a plurality of protocolsaccording to the information and generates a dendriform editing view according to the template library, and adopts different fault-tolerance levels to correspond to different degrees of the protocol information deviating from the standard protocol. The user can edit the protocol information in a form of the dendriform editing view by the protocol information editing system designed by the method for ...

Method for correcting deviation of depth measuring sonar system

The invention provides a correcting method for the deviation of a depth measuring sonar system, which comprises the following steps: 1) acquiring data by a sea calibration test to obtain initial values of various parameters to be calibrated; 2) selecting a parameter to be calibrated and calculating correction quantity of the selected parameter to be calibrated according to current values of various parameters to be calibrated; and 3) judging whether the current correction quantity of the selected parameter to be calibrated is less than a preset threshold value or converged into certain value or not, if the judging result is not, substituting the value of the parameter to be calibrated by the sum of the current value of the parameter to be calibrated and the current correction quantity, andreturning the step 2) until all correction quantity of the parameter to be calibrated accord with the judging conditions. With the correcting method, various calibration parameters of the system arecomprehensively ...

LED display board and LED display

The invention discloses an LED display board and an LED display. The LED display board comprises a circuit board (1) and one or more driving chips (2), wherein a die (21) of each driving chip (2) is directly loaded on the first outer surface of the circuit board (1) or is embedded in the circuit board (1) for processing the received data signal. The invention can realize the LED display device with higher resolution and integration level, simultaneously effectively reduces the probability of deformation of the circuit board and reduces the negative effects caused by welding.

Preparation method of titanium-based titanium dioxide nanotube stannic oxide electrode

The invention relates to a preparation method of a titanium-based titanium dioxide nanotube stannic oxide electrode, belonging to the technical field of electro-catalysis electrode preparation. The method comprises the following steps: firstly adopting an anodic oxidation method to prepare a titanium dioxide nanotube on a titanium matrix, thus improving the specific surface area of the titanium matrix; and depositing stibium and tin in the titanium dioxide nanotube by an electro-deposition method successively, and performing thermal oxidation to lead the stibium doped stannic oxide to be bonded firmly with the titanium dioxide nanotubes directly connected with the titanium matrix. The stannic oxide crystal particles prepared by the electro-deposition method are dispersed evenly, and the electrode surface is compact and has no crack. The method overcomes the defect that crack is generated on the surface of the electrode prepared by the traditional brush coating thermal decomposition method ...

ANTICORROSIVE PAINT FOR THE FOUNDING OF NONFERROUS METAL AND ALLOY

POLAR SILANES AND THEIR USE ON SILICA SUPPORTS

Compounds and compositions as c-kit and PDGFR kinase inhibitors

Compositions and methods for modulating c-kit and PDGFR receptors

Vapor chamber

The invention discloses a vapor chamber. The vapor chamber comprises a vapor chamber main body and a locking structure, wherein the locking structure is fixedly connected with any position on the outer surface of the vapor chamber main body by a stud welding method; and the stud welding method comprises the following steps of: 1) contacting one end to be fixed of the locking structure and the outer surface of the vapor chamber main body; 2) powering on the locking structure and conducting to the outer surface of the vapor chamber main body until the outer surface of the vapor chamber main body is melted so as to form a melting pool matched with the shape of the contact end of the locking structure; 3) exerting pressure at one end, which is not contacted with the surface of the vapor chamber main body, of the locking structure so that the locking structure is immersed into the melting pool; and 4) stopping powering on, and standing until the melting pool is condensed. The vapor chamber has ...

Burner for using mixed high, low pressure gas and fuel

Diarylamine-containing compounds and compositions, and their use as modulators of c-kit receptors

A crop growth model description and interpretation method

This invention discloses a kind of description and explanation method of crop growth model of visual crop growth system that based on PC. It comprises the following steps: 1. Describing the crop growth model by XML; 2. Building the explain system based on growth model XML description script. Building the visual crop growth system by this invention, the agriculturist can programmed organize the agricultural knowledge according to the growth model description XML script outline.

Constant temperature regulating valve

The invention discloses a constant temperature regulating valve, which comprises a valve body, a thermosensitive valve core, a movable valve core, a valve rod, a valve cover and a hand wheel, wherein a valve cavity is formed in the valve body; a water inlet and a water outlet which are communicated with the valve cavity are formed on the valve body; a clapboard is arranged between the water inlet and the water outlet; a current limiting hole is formed on the clapboard and is used for communicating the water inlet with the water outlet; the thermosensitive valve core is inserted into the current limiting hole, and the height of the thermosensitive valve core in the valve cavity is changed according to the temperature of water in the valve cavity; a return spring is arranged at the lower end of the thermosensitive valve core and is used for pushing the thermosensitive valve core upwards; the upper end of the thermosensitive valve core passes through the movable valve core to be pressed against ...

Process for manufacturing ten-thousand-ton grade special multipurpose vessel

The invention discloses a manufacture process for a 10,000-ton class special multipurpose vessel, which is characterized by comprising the following steps: a. section construction and preparation for parts of the vessel are carried out in a section field, and all double-deck support devices are prearranged in a cargo tank of the vessel; b. section spray coating is carried out in a spray coating field; c. a hull is assembled on a slipway; d. the hull is launched; and e. a vessel test and acceptance check are performed on an outfitting quay. The production process for the 10,000-ton class special multipurpose vessel adopt the way that the cargo tank is provided with the double-deck support devices, which ensures the integrity of paint of the vessel and shortens the construction cycle of the vessel; and the prearrangement of the double-deck support devices is carried out on a horizontal plane and avoids operation in a cabin, thereby greatly improving working environment and guaranteeing the ...

Method and apparatus for backing up application code upon power failure during a code update

Method of purification of recombinant viral vectors containing a therapeutic gene

Pouring sand mold box for barrel-shaped casts

Abstract The invention provides a pouting sand mold box for barrel-shaped casts which can ensure that the wall thickness at the highest point of the upper part of a cast in an upper sand mold box achieves the required minimum value, eliminate the need of supplementation and correction and reduce the production cost. The pouring sand mold box for the barrel-shaped casts comprises the upper sand mold box and a lower sand mold box, a sand core is arranged in a mold cavity formed by the upper sand mold box and the lower sand mold box, and the height of an inner cavity of the upper sand mold box is higher than that of the inner cavity of the lower sand mold box.

Stator punching of motor

The invention relates to a stator punching of a motor, which comprises a stator punching body, wherein 36 stator punching slots are arranged in the stator punching body. In the stator punching slots, the slot width bs1 is 6.2mm; b01 is 3.2mm; bs2 is 8.2mm; zs1 is 30 degrees; hs0 is 0.8mm; and hs12 is 18.5mm. The invention only needs to change the punching die of the stator punching without changing the original assembling mode of the motor. The punching is used in a stator core with center height of 132 and two poles of a high-efficiency motor, can improve the efficiency of the motor, and can ensure small electromagnetic noise, low starting current and large torque in the long-term service process.

Method, system and apparatus for analyzing article coding

The invention relates to an article code analytic device, an article code analytic system and an article code analytic method, wherein the article code analytic device comprises a judgment module and an analytic module and an external system code processing module which are respectively connected with the judgment module. The invention also relates to the article code analytic system which comprises more than one article code analytic devices connected with each other. The invention also provides the article code analytic method which comprises the following steps: judgment is made whether the article code required to be analyzed by a code analysis request received belongs to an internal system code or an external system code; code information of the article code in the internal system issearched and then transmitted to a user device which gives out the code analysis request; or ownership information of the article code in the external system is acquired and the code analysis requestis ...

Broadband set-top box front-end storage system

Forwarding method and device thereof

The invention discloses a forwarding method and a device thereof, the method comprises the steps: determining the proportion of the weight of each next-hop in acquired multipath routing in the weights of all the next-hops; determining the total number of pointers and the number of pointers assigned to each next-hop in accordance with the proportion of the weight of each next-hop; and forwarding in accordance with the pointer corresponding to each next-hop. The method and the device simplify the complexity in designing hardware ASIC forwarding chip.

Erection method of stiffening girder of suspension bridge and device thereof

The invention discloses an erection method of a stiffening girder of a suspension bridge and a device thereof. The method comprises the following steps: 1) a track cable is erected below the position of a main cable of the suspension bridge; 2) a sling suspended on the main cable is taken as a middle suspension center of the track cable; 3) the middle suspension center is connected with the track cable by a saddle; 4) two ends of the track cable are arranged on anchorage systems at two banks; 5) a stiffening girder section is suspended by an overhead crane system supported on the track cable, and a traction system or a pushing system draws or pushes the overhead crane system to carry the stiffening girder section to a required position; and 6) the stiffening girder segment carried to the position is vertically lifted by a lifting device to be connected with the sling for achieving system transform. The method and the device have the obvious advantages of safe construction, cost saving, ...

Damage control die

The invention provides a damage control die, which comprises a die matrix and at least one pair of symmetric flat projections arranged on the die matrix, wherein the flat projections have an alumina alloy structure respectively. The die is difficult to damage during stripping, continuous production can be guaranteed, and production cost is reduced.

Directional motion vector mode of rotating magnetic field of AC induction motor

The physical and mathematical knowledge are used to explain that the bidirectional rotation magnetic field theory in the current motor theory is infeasible in physics, namely the magnetic-field vector in bidirectional motion at the air gap can not keep in the same position of the original magnetic-field vector so that the application condition of the magnetic-field vector superposition principle can not be satisfied, the vector is equal in mathematics and the theory is not equivalent in physics. The directional motion vector mode is established by analyzing the motion characteristics of the pulsating magnetic field of the AC induction motor so as to describe the motion characteristics of the rotation magnetic field of the AC induction motor. The motion characteristics are as follows: the stator winding of the AC induction motor can only generate the pulsating magnetic field; the pulsating magnetic field is distributed along the circumference of the air gap, the amplitude connecting line ...

Bridge prefabricated foundation and bed-burying method thereof

The invention discloses a bridge prefabricated foundation and a bed-burying method thereof. The bridge prefabricated foundation consists of a bridge lower part pier body, an undercut bearing platform and a cavity formed by enclosing the pier body and the bearing platform. The undercut bearing platform is reserved with a guide hole, an exhausting recharging hole and a supporting liner plate. The bed-burying method comprises the following steps of: integrally prefabricating the lower part pier body and the bearing platform in a factory; excavating a foundation ditch, and then paving a crash padlayer; and sinking a pile which passes through the crash pad layer and is inserted into a sea (or river) bed. A range of 5 to 30 m below a designed height mark of the top of the pile and is filled with core filling concrete, and a supporting pile and a bearing pile are cut to the designed height mark underwater. The prefabricated foundation is positioned through a guide pile, and is placed on thesupporting ...

Lanthanum and cerium composite alloy additive and preparing method thereof

Process for synthesizing single-phase sodalite from fly ash

The invention belongs to the field of production and preparation of inorganic functional materials, and particularly relates to a process for preparing single-phase sodalite from fly ash, which comprises the following steps: pretreating fly ash by an alkaline fusion method; proportionally adding the activated fly ash, aluminum hydroxide and sodium hydroxide solution into a polytetrafluoroethyleneinner container, evenly mixing, and carrying out hydrothermal crystallization in a sealed constant-temperature drying oven; and finally, filtering the product, washing until the product becomes neutral, and drying to obtain the single-phase sodalite material. The invention successfully synthesizes the low-cost single-phase sodalite zeolitization material by using solid waste-fly ash as the raw material for production. The process has the advantages of low cost, abundant sources of raw material, controllable product performance, no secondary pollution and the like, is simple and easy to operate, ...

Cement type surface simple drawing mold

The simple drawing mold with cement mold surface includes one lower mold, one mold pin, one clamping ring, one upper mold, one cement mold surface fixing rod, one upper mold lining, and one cement mold surface. The lower mold and the clamping ring form one steel mold structure with steel mold surface; the upper mold is one steel mold structure with cement mold surface; the cement mold surface has one upper mold lining embedded during depositing cement; and the lower mold has corresponding mold surface hole with close fitted mold pin. The present invention has the following obvious advantages: saving in material, low numerically controlled machining cost, low cost and short making period.

Delicious sweet potato stripe

The invention discloses a fragrant, crisp and sweet potato chip, relating to a deeply processed product from a sweet potato (commonly referred to as pachyrhizus). The processing details include the following: process the sweet potato into slices or lumps, braise the slices or the lumps, dry the cooked slices or the lumps in wind, under sun or with a stove until the surface is dry and the hardness is proper for eating, at last roast the slices or the lumps in an oven until the surface becomes golden yellow or medium-fry the slices or the lumps in edible oil until the surface becomes golden yellow, thus the invention is a good food for travel and for health care.

Zinc Oxide Sulfur Sensor Measurement System

A measurement system is disclosed for determining a sulfur concentration in a liquid, such as a liquid fuel. The measurement system includes a first electrode that is at least partially coated with zinc oxide and, more specifically, zinc oxide microstructures. The zinc oxide microstructures have a crystal lattice structure that is oriented in the (002) plane. The first electrode may be connected to an electrometer which, in turn, may be connected to a second electrode. The second electrode may be disposed on a common substrate with the first electrode or may be in the form of a plate disposed substantially parallel to the first electrode.

ELECTROCHEMICAL SULFUR SENSOR

This disclosure relates to sulfur sensors that utilize sensing materials that can be used to detect a wide range of concentrations including ultra low concentrations of sulfur in liquids, such as below even 15 ppm. The sulfur sensors comprise a sensing electrode having a material that contributes an electronic output to the analysis and a material that contributes an ionic output to the analysis. 1. An electrochemical sulfur sensor for determining a concentration of sulfur compounds in a liquid , the electrochemical sulfur sensor comprising:a reference electrode; anda sensing material including an electronic conductive material and a metal cation, the sensing material being in association with a sensing electrode;wherein the sensing material exhibits both electronic and ionic conductivity in the presence of the liquid.2. The electrochemical sulfur sensor of wherein the form of the electronic conductive material is selected from the group consisting of graphite foam claim 1 , metal coupons claim 1 , tape claim 1 , fiber claim 1 , fiber mesh claim 1 , powder claim 1 , sintered powder claim 1 , and thick and thin film depositions.3. The electrochemical sulfur sensor of wherein the electronic conductive material is a graphite foam.4. The electrochemical sulfur sensor of wherein the metal cation is selected from the group consisting of Fe claim 1 , Cu claim 1 , Ag claim 1 , Au claim 1 , Ni claim 1 , Zn claim 1 , Pb claim 1 , Mo claim 1 , and combinations thereof.5. The electrochemical sulfur sensor of wherein the reference electrode is a wire comprising Ag claim 1 , Au claim 1 , Pt claim 1 , and combinations thereof.6. The electrochemical sulfur sensor of wherein the electronic conductive material is affixed to a copper-based metal tape.7. The electrochemical sulfur sensor of further including an insulating layer between the reference electrode and the sensing electrode affixed to a copper-based metal tape.8. The electrochemical sulfur sensor of wherein the insulating ...

METHOD FOR PERFORMING DYNAMIC TUNNEL MESSAGE FORWARDING AND SWITCH THEREOF

A method and switch for realizing dynamic tunnel message forwarding are disclosed; the method includes: presetting an aggregation routing table item of a dynamic tunnel in an ASIC hardware forwarding table of a layer-3 switch located at the edge of the IPv6 network to point to the CPU; after receiving an IPv6 message, if the switch judges that the message points to the dynamic tunnel according to IPv6 route lookup, sending the message upward to the CPU according to the aggregation routing table item; after receiving the message, the CPU, by using a software routing mode, storing a corresponding relation between acquired layer-2 information and a network prefix of an IPv6 destination address of the message and synchronizing the corresponding relation to the ASIC hardware forwarding table, and forwarding the message out from an output port to which the layer-2 information corresponds. 1. A method for realizing dynamic tunnel message forwarding , comprising:presetting an aggregation routing table item of a dynamic tunnel in an Application Specific Integrated Circuit (ASIC) hardware forwarding table of a layer-3 switch located at the edge of an IPv6 network to point to a Central Processing Unit (CPU);the switch receiving an IPv6 message, if the switch judges that the received IPv6 message points to the dynamic tunnel according to IPv6 route lookup, sending the IPv6 message upward to the CPU according to the aggregation routing table item; andthe CPU receiving the IPv6 message, by using a software routing mode, storing a corresponding relation between acquired layer-2 information and a network prefix of an IPv6 destination address of the IPv6 message and synchronizing the corresponding relation to the ASIC hardware forwarding table, and forwarding the IPv6 message out from an output port to which the layer-2 information corresponds.2. The method according to claim 1 , wherein claim 1 , after the step of the switch receiving the IPv6 message claim 1 , the method further ...

Natural rubber initial processing machinery and method

An initial processing of natural raw rubber through an initial processing machine, comprising the steps of: (a) providing a coagulated latex which contains water and volatile compositions; (b) dewatering the coagulated latex through a screw-pressing process to remove free water; (c) forming a first pretreated latex material; (d) aging the first pretreated latex material through an aging process to remove water and volatile compositions; and (e) forming a final product of aged latex material. The screw-pressing process makes use of the temperature and pressure increase along the elongated channel structure. The aging process makes use of the further temperature and pressure increase of the rubber materials, together with the screwing effect of the screw-shaft component, the squeezing effect of the nozzle and additional heating at a particular location, which is around the mouthpiece of the nozzle to complete the aging process, which is energy saving, effective and efficient. 1. A drying process for initial processing of natural raw rubber , comprising:(a) providing a coagulated latex, wherein the coagulated latex contains water and volatile compositions;(b) dewatering the coagulated latex through a screw-pressing process such that free water is removed;(c) forming a first pretreated latex material;(d) aging the first pretreated latex material through an aging process such that water and volatile compositions are removed; and(e) forming a final product of aged latex material.2. The drying process claim 1 , as recited in claim 1 , wherein in step (a) claim 1 , the coagulated latex is in the form of granule.3. The drying process claim 1 , as recited in claim 1 , after step (a) claim 1 , further comprising the step of:dewatering the coagulated latex through mechanical vibration.4. The drying process claim 2 , as recited in claim 2 , after step (a) claim 2 , further comprising the step of: dewatering the coagulated latex through mechanical vibration.5. The drying process ...

COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS

The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFRβ) kinases. 3. The compound of claim 1 , wherein Ris selected from —CHand F4. The compound of claim 3 , wherein Ris —CH.5. The compound of claim 1 , wherein each Ris independently selected from H claim 1 , F and —CH.6. The compound of claim 5 , wherein each Ris H.7. The compound of claim 1 , wherein Ris selected from an unsubstituted 4-6 membered heterocycloalkyl with 1-2 heteroatoms independently selected from N and O claim 1 , a piperidinone claim 1 , a oxazolidin-2-one claim 1 , pyrrolidinone claim 1 , a pyrrolidin-2-one and a substituted 4-6 membered heterocycloalkyl with 1-2 heteroatoms independently selected from N and O claim 1 ,{'sup': 3', '4', '4', '7', '5', '9', '4', '9', '4', '4', '4', '4', '4', '9', '4', '8', '9', '8', '4', '7', '8', '4', '4', '9', '4', '9', '4, 'sub': 1', '6', '1', '6', '2', 'n', '2', 'n', '2', '2', 'n', '2', 'n', '2', '2', '2', '2', '2', '2', '2', '2', 'n', '2', '2', 'n', '1, 'wherein the substituted 4-6 membered heterocycloalkyl of Ris substituted with 1-4 substituents independently selected from C-Calkyl, halo, —CN, C-Chaloalkyl, —C(═O)OR, —C(═O)R, —C(═O)R, —C(═O)OR, —(CR)—OR, —C(═O)O(CR)OR, —C(═O)NR, —NRC(═O)OR, —NRC(═O)(CR)OR, —R, —(CR)R, —S(═O)R, —S(═O)R, —S(═O)R, —S(═O)N(R), —S(═O)NHC(═O)OR, —S(═O)(CR)OR, —S(═O)(CR)C(═O)ORand a Calkyl bridge.'}8. The compound of claim 7 , wherein each Ris independently selected from H claim 7 , methyl claim 7 , ethyl claim 7 , propyl claim 7 , butyl claim 7 , i-propyl and t-butyl.9. The compound of claim 7 , wherein each Ris ...

COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS

The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFRβ) kinases. 3. The compound of claim 1 , wherein Ris selected from —CHand F.4. The compound of claim 3 , wherein Ris —CH.5. The compound of claim 1 , wherein each Ris independently selected from H claim 1 , F and —CH.6. The compound of claim 5 , wherein each Ris H.7. The compound of claim 1 , wherein Ris selected from an unsubstituted C-Ccycloalkyl claim 1 , a cyclobutanone claim 1 , a cyclopentanone and a substituted C-Ccycloalkyl claim 1 ,{'sub': 3', '8', '1', '6', '1', '6', '2', 'n', '2', 'n', '2', '2', 'n', '2', 'n', '2', 'n', '2', '2', '2', '2', 'n', '1', '6', '1', '6', '1', '6, 'sup': 3', '4', '9', '4', '9', '4', '4', '4', '9', '5', '4', '4', '4', '9', '4', '4', '9', '4', '4', '4', '4', '9', '4', '8, 'wherein the substituted C-Ccycloalkyl of Ris substituted with 1-4 substituents independently selected from C-Calkyl, halo, C-Chaloalkyl, —OR, —(CR)OR, —O(CR)OR, —N(R), ═N—OR, ═N—O—(CR)R, —NRC(═O)OR, —NRC(═O)(CR)OR, —NR(CR)OR, —NRS(═O)R, —N(C(═O)OR), ═CH, ═CH(CR)OR, R, deuterated C-Calkoxy, a spiro attached dioxolane, a spiro attached dioxolane which is substituted with C-Calkyl, a spiro attached dioxane, a spiro attached tetrahyrofuranly, a spiro attached cyclobutanone, a spiro attached cyclobutanol, an unsubstituted 5-6 membered heterocycloalkyl with 1-2 heteroatoms independently selected from N and O and a 5-6 membered heterocycloalkyl with 1-2 heteroatoms independently selected from N and O substituted with 1-3 substituents independently selected from C-Calkyl.'}8. The compound of claim 7 , ...

START-UP STRATEGY FOR HYBRID POWERTRAIN

A start-up method for a hybrid powertrain in which hydraulic pressure is generated in a casual start-up by an electric oil pump motor where certain predetermined conditions are satisfied and the casual start-up is abandoned and hydraulic pressure is generated by an engine where the predetermined conditions are not satisfied. The casual start-up is also abandoned where a vehicle operator seeks propulsion shortly after start-up and before an oil pump is rotating within a predetermined threshold of an oil pump target RPM. 1. A method for starting-up a hybrid powertrain comprising an engine , an over-running clutch coupled to said engine , an electric oil pump motor coupled to said over-running clutch and an oil pump coupled to said electric oil pump motor , said method comprising:evaluating whether predetermined conditions for a casual start are satisfied upon a start-up command from a vehicle operator;starting said engine if said predetermined conditions are not satisfied; andactivating said electric oil pump motor for a casual start without activating said engine if said predetermined conditions are satisfied.2. The method of claim 1 , further comprising if said predetermined conditions are satisfied:calculating the difference between an oil pump target rotations per minute and the rotations per minute of said electric oil pump motor;comparing said difference to a threshold value;when said vehicle operator issues a shift command, starting said engine and then deactivating said electric oil pump motor once the rotations per minute of said engine equal or exceed the rotations per minute of said electric oil pump if said difference is greater than said threshold value; andcontinuing said casual start if said difference is less than said threshold value or said vehicle operator does not issue a shift command.3. The method of claim 2 , further comprising starting said engine and terminating said method after a predetermined amount of time has passed from said start-up ...

SINGLE PLANE TISSUE REPAIR PATCH

A novel single plane tissue repair device such as a patch is disclosed. The device has a base member with an opening therethrough, and a closure member associated with the opening. The mesh has a biaborbable polymeric adhesion barrier attached to the bottom side of the base member about its periphery to form a pocket that is accessible through the opening. The mesh may be used in open surgical procedures for hernia repairs and other repairs of body wall defects. 1. A tissue defect repair device , comprising:a substantially flat base member having a top side, a bottom side, an outer periphery and a peripheral edge;an opening located in said base member;a closure member associated with said opening; and,a polymeric, bioabsorbable adhesion barrier member having a top side, a bottom side, an outer periphery, and a perhipheral edge, said adhesion barrier mounted to the base member about their respective outer peripheries such that a pocket is formed between the top side of the adhesion barrier and the bottom side of the base member, said pocket accessible through the opening;2. The tissue repair device of claim 1 , additionally comprising a polymeric film on at least one side of the base member.3. The tissue repair device of claim 1 , wherein the adhesion barrier member is substantially flat.4. The tissue repair device of claim 1 , wherein the adhesion barrier member is curved.5. The tissue repair device of claim 1 , wherein the adhesion barrier member is shaped.6. The device of claim 1 , wherein the base member comprises a mesh.7. The device of claim 1 , wherein the base member comprises a fabric.8. The device of claim 8 , wherein the fabric is woven.9. The device of claim 8 , wherein the fabric is nonwoven.10. The device of claim 1 , wherein the base member comprises an expanded polymeric film.11. The device of claim 1 , wherein the base member comprises a biocompatible claim 1 , nondegradable polymer.12. The device of claim 1 , wherein the base member comprises a ...

COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS

The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFRβ) kinases. 3. The method of claim 1 , wherein Ris selected from —CHand F.4. The method of claim 3 , wherein Ris —CH.5. The method of claim 1 , wherein each Ris independently selected from H claim 1 , F and —CH.6. The method of claim 5 , wherein each Ris H.7. The method of claim 1 , wherein Ris selected from an unsubstituted 4-6 membered heterocycloalkyl with 1-2 heteroatoms independently selected from N and O claim 1 , a piperidinone claim 1 , a oxazolidin-2-one claim 1 , pyrrolidinone claim 1 , a pyrrolidin-2-one and a substituted 4-6 membered heterocycloalkyl with 1-2 heteroatoms independently selected from N and O claim 1 ,{'sup': 3', '4', '4', '4', '7', '5', '9', '4', '9', '4', '4', '4', '4', '9', '4', '8', '9', '8', '4', '7', '8', '4', '4', '9', '4', '9', '4, 'sub': 1', '6', '1', '6', '2', 'n', '2', 'n', 'NR42', '2', 'n', '2', 'n', '2', '2', '2', '2', '2', '2', '2', '2', 'n', '2', '2', 'n', '1, 'wherein the substituted 4-6 membered heterocycloalkyl of Ris substituted with 1-4 substituents independently selected from C-Calkyl, halo, —CN, C-Chaloalkyl, —OR, —C(═O)OR, —C(═O)R, —C(═O)R, —C(═O)OR, —(CR)OR, —C(═O)O(CR)OR, —C(═O), —NRC(═O)OR, —NRC(═O)(CR)OR, —R, —(CR)R, —S(═O)R, —S(═O)R, —S(═O)R, —S(═O)N(R), —S(═O)NHC(═O)OR, —S(═O)(CR)OR, —S(═O)(CR)C(═O)ORand a Calkyl bridge.'}8. The method of claim 7 , wherein each Ris independently selected from H claim 7 , methyl claim 7 , ethyl claim 7 , propyl claim 7 , butyl claim 7 , i-propyl and t-butyl.9. The method of claim 7 , wherein each Ris cyclopropyl ...

INORGANIC COATING COMPOSITION WHICH CAN BE CURED AT LOW TEMPERATURE AND A PREPARATION METHOD THEREOF

The present invention relates to coating composition. And in particular, to an inorganic coating composition which can be cured at low temperature and a preparation method thereof. In order to solve the problems that the organic coating is harmful for the environment, the inorganic coating has bad flexibility, and the traditional ceramic coatings need heat and is inconvenient for curing in prior art, the present invention provide an inorganic coating composition which can be cured at low temperature and a preparation method thereof. The inorganic coating composition comprises the ingredient as below: 70-80 wt % of inorganic solution; 5-10 wt % of functional additives, which are potassium titanate, alumina, or a compound thereof; 10-20 wt % of inorganic pigment; 0.5-2.0 wt % of other functional additives. The said inorganic solution comprises the following ingredients: 30-40 wt % of organic alkoxy-silane, 15-20 wt % of organic solvent, and 25-30 wt % of silica sol. The inorganic coating composition is able to be cured at low temperature, the film formed by it has excellent flexibility, and the film will not release harmful organic gases, and is beneficial to the environmental. 1. An inorganic coating composition which is curable at low temperature , wherein the inorganic coating composition comprises:70-80 wt % inorganic solution, wherein the inorganic solution comprises 30-40 wt % organic alkoxy-silane, 15-20 wt % organic solvent, and 25-30 wt % silica sol;5-10 wt % first functional additive selected from potassium titanate, alumina, or mixture thereof;10-20 wt % inorganic pigment; and0.5-2.0 wt % other functional additive.2. The inorganic coating composition of claim 1 , wherein the alkoxy-silane is represented by formula RSi(OR) claim 1 , where Rand Rrepresent a substituted or non-substituted alkyl group or aryl group comprising n C claim 1 , where n is 1-10; m is 0-3.3. The inorganic coating composition of claim 2 , wherein the Rand/or Rare at least one of ...

CHROMATOGRAPHIC MATERIAL HAVING IMPROVED PH STABILITY, METHOD FOR PREPARATION THEREOF AND USES THEREOF

A chromatographic material including a substrate having a surface and having a polymeric layer covalently bound to the surface; the polymeric layer comprising polymer molecules covalently attached to the surface of the substrate, each polymer molecule being attached to the surface via multiple siloxane bonds and each polymer molecule being connected to one or more functionalizing compounds that each comprise a functional group, wherein the polymeric layer is formed by covalently attaching polymer molecules to the surface of the substrate via multiple siloxane bonds, each polymer molecule containing multiple first reactive groups, and reacting the first reactive groups of the attached polymer molecules with at least one functionalizing compound that comprises a second reactive group that is reactive with the first reactive groups and that further comprises a functional group. Preferred conditions of reacting the polymer with the substrate include elevated temperature and reduced pressure. 1. A chromatographic material comprising:a substrate having a surface and the substrate having a polymeric layer covalently bound to the surface;the polymeric layer comprising polymer molecules covalently attached to the surface of the substrate, each polymer molecule being attached to the surface via multiple siloxane bonds and each polymer molecule being connected to one or more functionalizing compounds that each comprise a functional group.2. The chromatographic material according to claim 1 , wherein the polymeric layer is formed by covalently attaching polymer molecules to the surface of the substrate via multiple siloxane bonds claim 1 , each polymer molecule containing multiple first reactive groups claim 1 , and reacting the first reactive groups of the attached polymer molecules with at least one functionalizing compound that comprises a second reactive group that is reactive with the first reactive groups and that further comprises a functional group.3. The ...

COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS

The invention provides compounds of formulae (I) and (II) and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFRβ) kinases. 2. The compound of wherein:{'sup': 20', '9', '4', '4', '9', '4', '8', '9', '8', '9', '4', '9', '9', '6', '9', '4', '4', '9', '4', '4', '9, 'sub': 1', '6', '1', '6', '1', '6', '1', '6', '2', 'n', '2', 'n', '2', 'n', '2', 'n', 't', '2', 'n', '2', 'n', '2', 'n', '2', '2', 'n', '2', 'n, 'm is 1 and Ris selected from H, halo, C-Calkyl, C-Chaloalkyl, C-Chaloalkoxy, deuterium, deuterated C-Calkyl, —CN, —(CR)OR, —C(O)R, —(CR)C(═O)OR, R, —(CR)R, —((CR)O)R, —(CR)O(CR)R, —(CR)C(═O)R, —C(═O)N(R), —(CR)OR, —ORand —(CR)CN,'}{'sup': '20', 'or m is 4 and Ris deuterium;'}{'sup': '1', 'sub': 1', '6, 'Ris selected from C-Calkyl and halo;'}{'sup': '11', 'sub': 1', '6, 'each Ris independently selected from H, halo and C-Calkyl;'}{'sub': '1', 'Lis a bond, —NH— or —C(O)NH—;'}{'sup': 2', '9', '4', '9', '6', '9', '4', '9', '9', '4', '9', '4', '9', '4', '9', '4', '9', '4', '9', '4', '9', '9', '4', '9', '9', '6', '9', '9', '9', '6', '9', '9', '6', '6', '9', '9', '5', '6', '9', '5', '6', '6', '9', '5', '6', '9', '9', '5', '9', '6', '4', '9', '4', '4', '9', '4', '4', '9', '6', '4', '9', '4', '9', '4', '4', '9', '4', '4', '9', '4', '4', '9', '4', '6', '9', '4', '4', '9', '4', '9', '4', '9', '4', '9', '4', '5', '5', '4', '4', '9', '5', '6', '9', '4', '9', '6', '9', '4', '9', '11', '9', '4', '9', '9', '6', '9', '4', '9', '6, 'sub': 1', '6', '1', '6', '2', '8', '2', 'n', '2', 'n', '2', 'n', '2', '2', '2', 'n', '2', 'n', '2', 'n', '2', 'n', '2', 'n', '2', '2', 'n', '2', 'n', '2', 'n', '2', 'n', '2', ...

PRE-PROCESSING METHOD, METHOD FOR FORMING METAL SILICIDE AND SEMICONDUCTOR PROCESSING APPARATUS

A pre-processing method, a method for forming a metal silicide and a semiconductor processing apparatus are disclosed by the present invention. In the pre-processing method, a plasma etching process is performed on a semiconductor structure including a substrate. A first conductive portion and an isolation spacer covering a side surface of the first conductive portion are formed on a surface of an active area in the substrate. In the plasma etching process, a bias voltage applied to a surface of the semiconductor structure is adjusted by adjusting power outputs of two RF sources and is not lower than 150 V. In the metal silicide formation method, after a semiconductor structure including a first conductive portion and a second conductive portion is pre-processed in the manner as described above, a metal film is deposited thereon and annealed to result in the formation of the metal silicide. 1. A pre-processing method for a semiconductor structure , comprising:providing a semiconductor structure, wherein the semiconductor structure comprises a substrate containing an active area, a first conductive portion formed over a portion of a surface of the active area, and an isolation spacer formed by an inner silicon oxide layer, a silicon nitride layer and an outer silicon oxide layer sequentially covering a side surface of the first conductive portion, wherein a tunneling oxide layer is interposed between the first conductive portion and the substrate; andpre-processing the semiconductor structure by performing a plasma etching process to remove a material from an exposed surface of the semiconductor structure, wherein the plasma etching process is performed by an apparatus equipped with two RF sources, and wherein a bias voltage applied to a surface of the semiconductor structure is adjusted by adjusting power outputs of the two RF sources and the bias voltage is controlled to be in a range of 150 V-260V.2. The pre-processing method of claim 1 , wherein the plasma ...

Inorganic coating composition which can be cured at low temperature and a preparation method thereof

The present invention relates to coating composition. And in particular, to an inorganic coating composition which can be cured at low temperature and a preparation method thereof. In order to solve the problems that the organic coating is harmful for the environment, the inorganic coating has bad flexibility, and the traditional ceramic coatings need heat and is inconvenient for curing in prior art, the present invention provide an inorganic coating composition which can be cured at low temperature and a preparation method thereof. The inorganic coating composition comprises the ingredient as below: 70-80 wt % of inorganic solution; 5-10 wt % of functional additives, which are potassium titanate, alumina, or a compound thereof; 10-20 wt % of inorganic pigment; 0.5-2.0 wt % of other functional additives. The said inorganic solution comprises the following ingredients: 30-40 wt % of organic alkoxy-silane, 15-20 wt % of organic solvent, and 25-30 wt % of silica sol. The inorganic coating composition is able to be cured at low temperature, the film formed by it has excellent flexibility, and the film will not release harmful organic gases, and is beneficial to the environmental. 111-. (canceled)12. An inorganic coating composition , wherein the inorganic coating composition comprises: 30-40 wt % organic alkoxy-silane,', '15-20 wt % organic solvent, and', '25-30 wt % silica sol., 'the inorganic solution comprises'}, '70-80 wt % inorganic solution, wherein'}13. The inorganic coating composition of claim 12 , wherein the inorganic coating composition further comprises:10-20 wt % inorganic pigment.14. The inorganic coating composition of claim 12 , wherein the inorganic coating composition further comprises:a first functional additive that is 5-10% wt of the inorganic coating composition,15. The inorganic coating composition of claim 12 , wherein the inorganic coating composition further comprises:an other functional additive that is 0.5-2.0 wt % of the inorganic coating ...

SYSTEM AND METHOD FOR PROVIDING ASIL D FAIL OPERATIONAL POWER SYSTEMS IN AUTOMATED VEHICLE APPLICATIONS

A vehicle control unit (e.g., a control unit for an automobile) receives feedback from an intelligent voltage/current sensor and a DC/DC controller. The DC/DC controller comprises a first switch for controlling power from a primary power source (e.g., low voltage power supplied from a high voltage battery). The intelligent voltage/current sensor senses power output from the primary power source. The vehicle control unit processes feedback from the intelligent voltage/current sensor and/or the DC/DC controller to determine if a failure has occurred in the primary power source. In response to determining the failure in the primary power source, the vehicle control unit disables the power from the primary power source using a second switch (e.g., a switch in a relay). 120-. (canceled)21. A system for providing fail operational power comprising:a DC/DC controller, wherein the DC/DC controller comprises a DC/DC converter and a first switch that controls power from a high voltage vehicle battery pack to a low voltage power network, wherein the high voltage vehicle battery pack and the DC/DC controller comprise a primary power source; andan intelligent voltage/current sensor with a first feedback path to the DC/DC controller that controls the first switch and a second feedback path to a driver that controls a relay switch for controlling the power from the primary power source to the low voltage power network;wherein the intelligent voltage/current sensor detects a failure in the primary power source, and, in response to detecting the failure in the primary power source, provides a signal for switching the relay switch that disables the power from the primary power source.22. The system of claim 21 , wherein the intelligent voltage/current sensor monitors the power from the high voltage vehicle battery pack and from the DC/DC controller.23. The system of claim 21 , wherein the detected failure is based on at least one of an identified voltage claim 21 , an identified ...

REPLACEABLE EMITTER ASSEMBLY FOR INTERFACING A SEPARATION COLUMN TO A MASS SPECTROMETER

An electrospray emitter assembly for interfacing a separation column to a mass spectrometer is disclosed. An emitter capillary includes an inlet end and an outlet end. A fitting is coupled to the inlet end of the emitter, configured to be removably connected to the separation column. A stop with a defined through hole is integrated proximate the inlet end of the emitter to produce a path for liquid to flow from the separation column to the emitter via the through hole where a voltage is applied to the liquid entering the emitter. 1. An electrospray emitter assembly for interfacing a separation column to a mass spectrometer , comprising:a. an emitter capillary having an inlet end and an outlet end; andb. a fitting coupled to the inlet end of the emitter, configured to be removably connected to the separation column;wherein a stop with a defined through hole is integrated proximate the inlet end of the emitter to produce a path for liquid to flow from the separation column to the emitter via the through hole where a voltage is applied to the liquid entering the emitter.2. The emitter assembly of wherein the fitting is a female threaded end fitting.3. The emitter assembly of wherein the female threaded end fitting is configured for engagement with a plug type capillary fitting of the separation column.4. The emitter assembly of wherein the emitter capillary comprises a fused silica capillary claim 1 , a metal capillary claim 1 , a ceramic capillary claim 1 , or a glass capillary.5. The emitter assembly of wherein the separation column is removably connected via a transfer line with the emitter capillary through the fitting.6. The emitter assembly of wherein the separation column is a liquid chromatography (LC) column.7. The emitter assembly of wherein the integrated stop has a thickness of up to 1.0 mm.8. The emitter assembly of wherein the integrated stop has a thickness of between 100 μm to 300 μm.9. The emitter assembly of wherein the through hole in the stop has a ...

ELECTROCATALYTIC FENTON OXIDATION-ELECTROCHEMICAL OXIDATION COUPLING PROCESS AND APPARATUS FOR EFFICIENT TREATMENT OF CHEMICAL WASTEWATER

The present invention discloses an electrocatalytic Fenton oxidation-electrochemical oxidation coupling process and apparatus for efficient treatment of chemical wastewater, and belongs to the field of sewage treatment. The process includes an electrocatalytic Fenton oxidation step, an electrochemical oxidation step, and a pH adjustment step. A spacing between a cathode and an anode in the electrocatalytic Fenton oxidation step is controlled, so that oxygen produced at the anode reacts at the cathode to produce HO. The treatment requirements can be met without external aeration or external addition of HO, and meanwhile, the efficiency of COD removal by electro-Fenton oxidation is effectively improved. Further, by connecting a pH adjusting tank with the electrocatalytic Fenton oxidation-electrochemical oxidation coupling apparatus in series, a coupling treatment process with near-zero production of iron sludge is realized 1. An electrocatalytic Fenton oxidation-electrochemical oxidation coupling process for efficient treatment of chemical wastewater , comprising an electrocatalytic Fenton oxidation step , an electrochemical oxidation step and a pH adjustment step , wherein a spacing between an anode and a cathode in the electrocatalytic Fenton oxidation step is controlled so that oxygen produced at the anode reacts at the cathode to produce HO.2. The electrocatalytic Fenton oxidation-electrochemical oxidation coupling process for efficient treatment of chemical wastewater according to claim 1 , wherein in the electrocatalytic Fenton oxidation step claim 1 , a narrow-channel electrocatalytic Fenton oxidation step with a spacing between the cathode and the anode less than or equal to 5 cm is adopted; and/or in the electrochemical oxidation step claim 1 , a narrow-channel electrochemical oxidation step with a spacing between the cathode and the anode less than or equal to 5 cm is adopted.3. The electrocatalytic Fenton oxidation-electrochemical oxidation coupling process ...

Representation Learning Using Multi-Task Deep Neural Networks

A system may comprise one or more processors and memory storing instructions that, when executed by one or more processors, configure one or more processors to perform a number of operations or tasks, such as receiving a query or a document, and mapping the query or the document into a lower dimensional representation by performing at least one operational layer that shares at least two disparate tasks. 1. A system comprising:one or more processors; and receiving a query or a document;', 'mapping the query or the document into a lower dimensional representation by using at least one operational layer that shares operations of at least two disparate tasks, wherein the at least one operational layer is based, at least in part, on a multi-task deep neural network (DNN); and', 'using the lower dimensional representation to perform at least one of the at least two disparate tasks., 'memory storing instructions that, when executed by the one or more processors, configure the one or more processors to perform operations comprising2. The system of claim 1 , wherein the operations further comprise performing two operational layers that individually share the at least two disparate tasks to map the query or the document into the lower dimensional representation.3. The system of claim 1 , wherein the at least two disparate tasks include query classifying and web searching.4. The system of claim 1 , wherein the operations further comprise representing the query or the document as a bag of words in a first operational layer.5. The system of claim 1 , wherein the at least one operational layer comprises hashing words of the query or the document into n-grams.6. The system of claim 5 , wherein the operations further comprise using a second operational layer that shares the at least two disparate tasks to map the query or the document into the lower dimensional representation claim 5 , and wherein the second operational layer comprises generating cross-talk semantic representations ...

BANDWIDTH CONTROL METHOD AND BANDWIDTH CONTROL DEVICE

Embodiments of the present application disclose a bandwidth control method and a bandwidth control device. The method includes: obtaining, by a bandwidth control device, an access request of a mobile terminal, where the access request is used to indicate that the mobile terminal requests to access the Internet by using a home gateway of a fixed terminal; obtaining, by the bandwidth control device, a first bandwidth of the fixed terminal, where the first bandwidth is a subscribed bandwidth of the fixed terminal; and adjusting, by the bandwidth control device, a bandwidth allocated to the fixed terminal from the subscribed bandwidth of the fixed terminal to a second bandwidth, where the second bandwidth is greater than the first bandwidth. In the embodiments of the present application, the impact of mobile terminal access on user experience of the fixed terminal can be reduced. 1. A bandwidth control method , comprising:obtaining, by a bandwidth control device, an access request of a mobile terminal, wherein the access request is used to indicate that the mobile terminal requests to access the Internet by using a home gateway of a fixed terminal;obtaining, by the bandwidth control device, a subscribed bandwidth of the fixed terminal; andadjusting, by the bandwidth control device, a bandwidth allocated to the fixed terminal from the subscribed bandwidth of the fixed terminal to a second bandwidth, wherein the second bandwidth is greater than the subscribed bandwidth of the fixed terminal.2. The method according to claim 1 , further comprising:controlling, by the bandwidth control device, a bandwidth, which the fixed terminal is allowed to use, to be the subscribed bandwidth of the fixed terminal.3. The method according to claim 1 , further comprising:obtaining, by the bandwidth control device, a subscribed bandwidth of each mobile terminal;calculating, by the bandwidth control device, a first bandwidth according to the subscribed bandwidths of all the mobile terminals; ...

Hyperparameter Transfer Via the Theory of Infinite-Width Neural Networks

Systems and method are provided that are directed to tuning a hyperparameter associated with a small neural network model and transferring the hyperparameter to a large neural network model. At least one neural network model may be received along with a request for one or more tuned hyperparameters. Prior to scaling the large neural network, the large neural network is parameterized in accordance with a parameterizing schemed. The large neural network is then scaled and reduced in size such that a hyperparameter tuning process may be performed. A tuned hyperparameter may then be provided to a requestor such that the hyperparameter can be directly input into the large neural network. By tuning a hyper parameter using a small neural network, significant computation cycles and energy may be saved. 1. A method for tuning one or more hyperparameters of a large neural network model , the method comprising:receiving a large neural network model;parameterizing the large neural network model according to a parameterization scheme;reducing a width of at least one layer of the large neural network model resulting in a smaller neural network model;performing a hyperparameter tuning process using the smaller neural network model to identify a tuned hyperparameter; andtransferring the tuned hyperparameter to the large neural network model.2. The method of claim 1 , wherein the hyperparameter tuning process includes performing an exhaustive search to identify an optimized hyperparameter.3. The method of claim 2 , further comprising using the optimized hyperparameter in the large neural network model during a training process.4. The method of claim 1 , wherein reducing the width of the at least one layer of the large neural network model is based at least upon an amount of available computing resources.5. The method of claim 1 , wherein the parameterization includes scaling at least one layer by a function of a width of the layer.6. A method for providing hyperparameters claim 1 , ...

Image Processing Method and Device

An image processing method performed by image processing device having an operating system includes receiving, by an image processing module of the operating system, an instruction of a first application program to call the image processing module of the operating system, where the instruction carries a to-be-displayed image and a resolution of the to-be-displayed image. The image processing method further includes when the resolution of the to-be-displayed image is less than a first threshold, performing, by the image processing module, super-resolution processing on the to-be-displayed image, and displaying an image obtained after the super-resolution processing. 1. An image processing method performed by an image processing device comprising an operating system , wherein the image processing method comprises:receiving, by the operating system, a to-be-displayed image from a first application program;performing, by the operating system and when the first application program has an image optimization permission, image optimization processing on the to-be-displayed image to obtain a processed image; anddisplaying the processed image.2. The image processing method of claim 1 , wherein performing the image optimization processing on the to-be-displayed image comprises performing super-resolution processing on the to-be-displayed image claim 1 , and wherein the image optimization permission is a super-resolution processing permission.3. The image processing method of claim 2 , wherein performing the super-resolution processing on the to-be-displayed image comprises performing the super-resolution processing on the to-be-displayed image when a resolution of the to-be-displayed image is less than a first threshold.4. The image processing method of claim 1 , further comprising determining claim 1 , by the operating system claim 1 , that the first application program has the image optimization permission based on an identifier of the first application program.5. The image ...

Natural Rubber Initial Processing Machinery and Method

An initial processing of natural raw rubber through an initial processing machine, comprising the steps of: (a) providing a coagulated latex which contains water and volatile compositions; (b) dewatering the coagulated latex through a screw-pressing process to remove free water; (c) forming a first pretreated latex material; (d) aging the first pretreated latex material through an aging process to remove water and volatile compositions; and (e) forming a final product of aged latex material. The screw-pressing process makes use of the temperature and pressure increase along the elongated channel structure. The aging process makes use of the further temperature and pressure increase of the rubber materials, together with the screwing effect of the screw-shaft component, the squeezing effect of the nozzle and additional heating at a particular location, which is around the mouthpiece of the nozzle to complete the aging process, which is energy saving, effective and efficient. 1. A machine for initial processing of natural raw rubber , comprising:a de-watering machine powered through a motor connecting to a reducer unit for providing a two-step de-watering process, comprising a vibration screen having first and second ends arranged for carrying out a first step of the two-step de-watering process, wherein coagulated latex granules are provided to said first end of said vibration screen which are then guided to transport from said first end to said second end of said vibration screen while going through the first step of dewatering process through said vibration screen; and a pressing screen connected to said vibration screen arranged for carrying out a screw-pressing process, wherein said pressing screen has an elongated body defining a pressing channel between first and second ends inside said elongated body, and comprises a screw unit inside said pressing channel and a nozzle operatively communicated with said screw unit provided at said second ends, wherein the ...

Compounds and compositions as c-kit kinase inhibitors

The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFRβ) kinases.

LEARNING GRAPH REPRESENTATIONS USING HIERARCHICAL TRANSFORMERS FOR CONTENT RECOMMENDATION

Knowledge graphs can greatly improve the quality of content recommendation systems. There is a broad variety of knowledge graphs in the domain including clicked user-ad graphs, clicked query-ad graphs, keyword-display URL graphs etc. A hierarchical Transformer model learns entity embeddings in knowledge graphs. The model consists of two different Transformer blocks where the bottom block generates relation-dependent embeddings for the source entity and its neighbors, and the top block aggregates the outputs from the bottom block to produce the target entity embedding. To balance the information from contextual entities and the source entity itself, a masked entity model (MEM) task is combined with a link prediction task in model training.

NANOMETER SIZE CHEMICAL MODIFIED MATERIALS AND USES

Ligand compositions and stationary phases comprising polyhedral oligomeric silsesquioxane moieties are incorporated in to chromatographic stationary phases, and these phases are incorporated into chromatography devices, such as columns. The compositions and devices are of use to separate molecular mixtures. 1. A method of separating analytes in a liquid sample , the method comprising: a solid support having an exterior surface;', 'a ligand comprising a polyhedral oligomeric silsesquioxane moiety;', 'a linker covalently bound to both the polyhedral oligomeric silsesquioxane moiety and the exterior surface of the solid support, wherein the polyhedral oligomeric silsesquioxane moiety is not a cross-linker., 'flowing the liquid sample through a chromatography column configured for use in liquid chromatography, the chromatography column containing therein a composition, the composition comprising2. The method of claim 1 , wherein the liquid sample comprises anions claim 1 , cations claim 1 , and uncharged molecules claim 1 , each retained by the composition.3. The method of claim 1 , wherein the linker comprises at least 4 carbon atoms in sequence.4. The method of claim 1 , wherein the linker comprises at least 8 carbon atoms in sequence.5. The method of claim 1 , wherein the linker comprises at least 10 carbon atoms in sequence.6. The method of claim 3 , wherein the linker comprises at least one heteroatom selected from N claim 3 , O claim 3 , S and a combination thereof.7. The method of claim 3 , wherein the linker comprises a first component and a second component where a linkage fragment joins the first component and the second component claim 3 , in which the linkage fragment is sulfur claim 3 , and the first component and the second component are each an unsubstituted alkyl.8. The method of claim 1 , wherein the solid support is in particulate form claim 1 , and wherein multiple support particles are disposed in a packed bed.9. The method of claim 1 , wherein the ...

METHOD AND SYSTEM FOR MULTIPLE SENSOR CORRELATION DIAGNOSTIC AND SENSOR FUSION/DNN MONITOR FOR AUTONOMOUS DRIVING APPLICATION

The system can diagnose sensor issues for a vehicle that can perform automatic driving functions based on areas where sensors overlap coverage and sensor performance limitation (SOTIF (Safety Of The Intended Functionality) in ISO 26262). First, the system can identify sensor overlap zones for advanced driver assistance systems/automated driving (ADAS/AD) applications that can be used for multiple sensor correlation and diagnostics. Once the zones have been identified, the system can define detailed multiple sensor correlation and diagnostics (e.g., the same kind of sensor, different kind of sensors, two-way plausible check, three-way voting, etc.). Finally, verified sensor output may be used in monitoring sensor fusion/deep neural network (DNN) outputs within defined a monitor zone. 1. A vehicle , comprising:a vehicle interior for receiving one or more occupants;a plurality of sensors to collect sensed information associated with an environment around the vehicle;an automated driving system; receives a first sensor signal from a first sensor;', 'receives a second sensor signal from a second sensor;', 'determines a zone in the environment where a first coverage of the first sensor overlaps with a second coverage of the second sensor; and', 'determines a degradation of the first sensor and/or second sensor based on a test of information, in the first sensor signal and the second sensor signal, associated with the zone., 'a sensor control processor in communication with the plurality of sensors and the automated driving system, wherein the sensor control processor2. The vehicle of claim 1 , wherein claim 1 , if the first sensor or the second sensor are degraded claim 1 , the sensor control processor alters information sent to the automated driving system.3. The vehicle of claim 1 , wherein the test is a plausibility check.4. The vehicle of claim 1 , wherein the sensor control processor further:receives a third sensor signal from a third sensor;determines a second zone ...

SPEAKER

A speaker includes a holder, and a vibration unit and a magnetic circuit unit that are fixedly connected to the holder. The vibration unit includes a first diaphragm, a voice coil, and an elastic support. The elastic support includes a flexible circuit board and a second diaphragm. The second diaphragm includes a first and a second fixing portion, and a suspension connecting the first to the second fixing portion. The flexible circuit board includes a first and a second connection portion, and an elastic arm connecting the first to the second connection portion. The elastic arm includes a first elastic arm extending from the first connection portion and a second elastic arm extending by reversely bending from the first elastic arm and connected to the second connection portion, and an orthographic projection of a reverse bending joint between the first and the second elastic arm is outside the suspension. 1. A speaker , comprising:a holder;a vibration unit comprising a first diaphragm, a voice coil positioned under the first diaphragm and configured to drive the first diaphragm to vibrate to produce sound, and at least one elastic support positioned under the voice coil and elastically supporting the voice coil; anda magnetic circuit unit;wherein the vibration unit and the magnetic circuit unit are fixedly connected to the holder;each of the at least one elastic support comprises a flexible circuit board and a second diaphragm stacked on the flexible circuit board; the second diaphragm comprises a first fixing portion fixedly connected to the voice coil, a second fixing portion spaced apart from the first fixing portion and fixedly connected to the holder, and a suspension connecting the first fixing portion to the second fixing portion; the flexible circuit board comprises a first connection portion fixedly connected to the voice coil, a second connection portion spaced apart from the first connection portion and fixedly connected to the holder, and at least one ...

APPLICATION OF FRUCTUS SCHISANDRAE TOTAL POLYSACCHARIDES IN PREPARATOIN OF MEDICINE OR NUTRACEUTICALS USED FOR TREATING COUGHING

The present invention relates to a new application of Fructus schisandrae total polysaccharides in preparation of medicine or nutraceuticals for treating coughing, and more specifically to a new application of Fructus schisandrae total polysaccharides in preparation of medicine or nutraceuticals for preventing and relieving coughing and eliminating airway inflammation. Experiments demonstrate that the Fructus schisandrae total polysaccharides can remarkably reduce the coughing times of a guinea pig with increased cough sensitivity induced by cigarette smoke and an acute cough guinea pig induced by citric acid smoke, prolong the latent period of cough, and significantly reduce the airway inflammation of the guinea pig with increased cough susceptibility induced by cigarette smoke, so that the Fructus schisandrae total polysaccharides can be used for preparing drugs for preventing cough, relieving cough and eliminating airway inflammation. 1. An application of Fructus schisandrae total polysaccharides in preparation of medicine or nutraceuticals used for treating coughing , characterized in that the medicine or nutraceuticals are used for treating acute cough , sub-acute cough or chronic cough; and the Fructus schisandrae total polysaccharides are prepared through the following steps: pulverizing Fructus schisandrae , degreasing the pulverized Fructus schisandrae with petroleum ether , decocting the degreased Fructus schisandrae for three times by using 8 times water , concentrating obtained decocted liquid , precipitating the concentrated solution by using 80% ethanol , filtering , performing deproteinization through a precipitation enzymatic method , decoloring by using active carbon , repeatedly washing by using 80% ethanol , and then drying to obtain the Fructus schisandrae total polysaccharides , and the content of polysaccharides in the Fructus schisandrae total polysaccharides is 89% through test on the basis of D-glucose.2. The application according to claim 1 ...

METALLURGY FOR PROCESSING BIORENEWABLE FEED

A process and apparatus for hydroprocessing a biorenewable feedstock involves an advantageous metallurgy. The biorenewable feed stream is hydrotreated in a hydrotreating reactor comprising a stainless steel having a composition of at least about 2 wt-% molybdenum which is sufficiently resistant to acidic corrosion. The hydrotreated biorenewable stream is hydroisomerized in a hydroisomerization reactor comprising a stainless steel having a composition of less than about 2 wt-% molybdenum. Most of the free fatty acids are deoxygenated in the hydrotreating reactor to make water, thus avoiding exposure of downstream equipment to acid attack. The stainless steel of said hydrotreating reactor may have a composition of no more than about 0.02 wt-% carbon. 1. A process for hydroprocessing a biorenewable feedstock , the process comprising:hydrotreating a biorenewable feed stream in a hydrotreating reactor in the presence of hydrogen to saturate olefins, deoxygenate oxygenated hydrocarbons and demetallize metallized hydrocarbons to produce a hydrotreated stream, said hydrotreating reactor comprising a stainless steel having a composition of at least about 2 wt-% molybdenum; andhydroisomerizing the hydrotreated stream in a hydroisomerization reactor over a hydroisomerization catalyst in the presence of a hydroisomerization hydrogen stream to provide a hydroisomerized stream, said hydroisomerization reactor comprising a steel having a composition of less than about 2 wt-% molybdenum.2. The process of wherein the steel of said hydroisomerization reactor has a composition of no more than about 1.2 wt-% molybdenum.3. The process of wherein the steel of said hydroisomerization reactor has a composition of no less than about 0.3 wt-% molybdenum.4. The process of wherein the stainless steel of said hydrotreating reactor has a composition of at least about 3 wt-% molybdenum.5. The process of wherein the stainless steel of said hydrotreating reactor has a composition of no more than ...

Prestressed Tube Section Structure and Construction Method thereof

The present application discloses a prestressed tube section structure and a construction method thereof. The prestressed tube section structure includes multiple successively connected segments. A shear-resistant structure and a water stop system are arranged between two segments; multiple prestressing tendons are arranged in the tube section along the circumferential direction of the tube section; and each prestressing tendon is communicated along the longitudinal direction of the tube section, and is partitioned into multiple sections at a position close to a segment joint. By the arrangement of the multiple successively connected segments of the present application, the shear-resistant structure and the water stop system are arranged between the two segments, so that a portion between two segments may bear a shear force and have watertightness; the arrangement of the multiple prestressing tendons in the tube section enables the multiple segments to be connected in series and spliced into a whole; in addition, each prestressing tendon is partitioned into multiple sections at the position close to each segment joint, so that the tube section has higher flexibility on the premise of not losing the overall rigidity, and the loading capacity and deformability of each segment are effectively improved; and a proper pressure is applied between two segments, so that the tube section has higher deformability to adapt to a subsea foundation bed. 1. A prestressed tube section structure , comprising multiple successively connected segments , a shear-resistant structure and a water stop system between two of the multiple successively connected segments , and multiple prestressing tendons in a tube section of the prestressed tube section structure along a circumferential direction of the tube section; wherein each prestressing tendon is communicated along a longitudinal direction of the tube section and is partitioned into multiple sections at a position close to a segment ...

Bearing Structural Member, Support, Joint Assembly and Tube Section Assembly

The present application discloses a bearing structural member, a support, a joint assembly and a tube section assembly, wherein the maximum counter force provided by the bearing structural member under an external load is an own designed threshold value, namely when the external load is greater than the designed threshold value of the bearing structural member, the bearing structural member deforms, and provides a counter force equal to the designed threshold value; the support includes at least one bearing structural member; and the joint assembly and the tube section assembly are both equipped with the support. When the external load is not high and is less than the designed threshold value, the bearing structural member may effectively suppress the deformation just like a rigid structural member; when the external load exceeds the designed threshold value, the bearing structural member may deform, and provide a stable counter supporting force less than the external load. The bearing structural member may be applied to the support, the joint assembly and the tube section assembly, plays a role in protecting the structures or key structural components, and may be widely applied to the fields of design of bridges, design of building structures, design of tunnels and the like. 1. A design method of a bearing structural member , wherein under the action of an external load , a maximum counter force provided by the bearing structural member is an own designed threshold value , and when the external load is greater than the designed threshold value of the bearing structural member , the bearing structural member deforms , and provides a counter force equal to the designed threshold value.2. The design method of the bearing structural member according to claim 1 , wherein when the external load is less than or equal to the designed threshold value of the bearing structural member claim 1 , the counter force is not greater than the external load.3. The design method of ...

ULTRAFILTRATION MEMBRANE AND A PREPARATION METHOD THEREOF

The present invention provides an ultrafiltration membrane comprising a sulfone polymer membrane matrix with pores and an organic polymer sealing layer, wherein the pores are filled with nanoadsorbents. The present invention further provides a method for preparing the ultrafiltration membrane, which includes the following steps: (1) synthesizing nanoadsorbents; (2) preparing the sulfone polymer membrane matrix by immersion-precipitation phase inversion; and (3) immobilizing nanoadsorbents in the pores of the sulfone polymer membrane matrix by reverse filling, then sealing the pores with organic polymers to form a multifunctional ultrafiltration membrane. In the present invention, colloidal gold, polyethylene glycol molecules and Pb(II) ions (and so forth) are utilized as models of viruses, macromolecular organic pollutants, and small molecular pollutants, respectively. It is shown that the multifunctional ultrafiltration membrane allows for removal of multiple pollutants from water and can simultaneously remove multiple pollutants under low pressure. 1. An ultrafiltration membrane , comprising a sulfone polymer membrane matrix with pores and an organic polymer sealing layer , wherein the pores are filled with nanoadsorbents.2. The ultrafiltration membrane according to claim 1 , wherein the nanoadsorbents are immobilized in the pores by reverse filling.3. The ultrafiltration membrane according to claim 1 , wherein the pores are formed by immersion-precipitation phase inversion.4. The ultrafiltration membrane according to claim 1 , wherein the nanoadsorbents are porous hollow nanoparticles.5. The ultrafiltration membrane according to claim 1 , wherein the pores are finger-like in shape.6. The ultrafiltration membrane according to claim 1 , wherein the pore sizes are 10˜40 μm×90˜150 μm.7. The ultrafiltration membrane according to claim 1 , wherein the porosity of the ultrafiltration membrane is 65%˜80% before the pores are filled with the nanoadsorbents and 35%˜50% ...

SYSTEM AND METHOD FOR PROVIDING ASIL D FAIL OPERATIONAL POWER SYSTEMS IN AUTOMATED VEHICLE APPLICATIONS

A vehicle control unit (e.g., a control unit for an automobile) receives feedback from an intelligent voltage/current sensor and a DC/DC controller. The DC/DC controller comprises a first switch for controlling power from a primary power source (e.g., low voltage power supplied from a high voltage battery). The intelligent voltage/current sensor senses power output from the primary power source. The vehicle control unit processes feedback from the intelligent voltage/current sensor and/or the DC/DC controller to determine if a failure has occurred in the primary power source. In response to determining the failure in the primary power source, the vehicle control unit disables the power from the primary power source using a second switch (e.g., a switch in a relay). 1. A system for providing fail operational power comprising:a vehicle control unit that receives feedback from an intelligent voltage/current sensor and a DC/DC controller, wherein the DC/DC controller comprises a first switch for controlling power from a primary power source, processes the feedback from the intelligent voltage/current sensor and/or the DC/DC controller to determine a failure in the primary power source, and in response to determining the failure in the primary power source, provides a signal for switching a second switch that disables the power from the primary power source.2. The system of claim 1 , wherein determining the failure in the primary power source is based on feedback from the intelligent voltage/current sensor and wherein the intelligent voltage/current sensor monitors power at a first vehicle battery and from the DC/DC controller.3. The system of claim 2 , wherein the feedback from intelligent voltage/current sensor is based on at least one of an identified voltage claim 2 , an identified amperage claim 2 , and an identified temperature.4. The system of claim 1 , wherein determining the failure in the primary power source is based on feedback from the DC/DC controller.5. ...

NETWORK DEVICE INTERMEDIARY FOR MEMORY ACCESS REQUESTS

Examples described herein relate to receiving memory access requests in a first number of connections from one or more front-end clients destined to a storage system and consolidating the memory access requests to a second number of connections between a network device and the storage system, wherein the second number is less than the first number. In some examples, consolidating the memory access requests includes combining read commands with other read commands destined to the storage system among connections of the first number of connections and combining write commands with other write commands destined to a same storage system among connections of the first number of connections. In some examples, consolidating the memory access requests includes performing protocol conversion to a format accepted by the storage system. In some examples, read or write commands are identified based on content of a header of a received packet, wherein the received packet includes a read or write command. 1. An apparatus comprising:a network device, when operational, to:receive memory access requests in a first number of connections from one or more front-end clients destined to a storage system andconsolidate the memory access requests to a second number of connections between the network device and the storage system, wherein the second number is less than the first number.2. The apparatus of claim 1 , wherein to consolidate the memory access requests to a second number of connections between the network device and the storage system claim 1 , the network device claim 1 , when operational claim 1 , is to:combine read commands with other read commands destined to the storage system andcombine write commands with other write commands destined to the storage system.3. The apparatus of claim 2 , wherein to consolidate the memory access requests to a second number of connections between the network device and the storage system claim 2 , the network device claim 2 , when operational ...

SEPARATION OF GLYCANS BY MIXED-MODE LIQUID CHROMATOGRAPHY

An exemplary multimodal chromatographic medium of the invention includes one or more strong anion exchange, weak anion exchange, strong cation exchange and/or weak cation exchange binding sites in combination with one or more reverse phase and/or hydrophilic interaction chromatography binding site. In an exemplary embodiment, the sites interact with one or more glycans in a mixture of glycans in a manner that allows separation of glycans in the mixture and analysis of the glycan mixture. The media are incorporated into devices and systems for chromatographic analysis. Also provided are methods of using the multimodal media of the invention to analyze glycans. 1. A multimodal chromatographic method of separating a first glycan component from a second glycan component of a glycan mixture , said method comprising:(a) contacting said glycan mixture with a multimodal chromatographic medium comprising an ion exchange chromatographic moiety bound to a first substrate and an uncharged chromatographic moiety bound to a second substrate, said uncharged chromatographic moiety selected from a reverse phase chromatographic moiety, a hydrophilic interaction chromatographic moiety and a combination thereof, and an aqueous eluent comprising an electrolyte and an organic solvent under conditions effective to achieve said separating, thereby separating said first glycan component and said second glycan component.2. The method according to claim 1 , wherein said ion exchange chromatographic moiety is an anion exchange moiety.3. The method according to claim 2 , wherein said ion exchange moiety is an amine.4. The method according to claim 1 , wherein said second chromatographic moiety is a hydrophilic interaction chromatographic moiety and is a urea.5. The method according to claim 1 , wherein said ion exchange chromatographic moiety is bound to said first substrate through a first linker moiety.6. The method according to wherein said uncharged chromatographic moiety is bound to said ...

METHOD OF PACKING CHROMATOGRAPHIC COLUMNS, PACKED CHROMATOGRAPHIC COLUMNS FOR USE AT HIGH PRESSURES AND USES THEREOF

A method of packing a chromatography column, including: dispersing chromatographic media particles in a slurry solution to form a slurry, filling a chromatography column with the chromatographic media particles by introducing the slurry to the column and applying a pressure to pack the chromatographic media particles in the chromatography column. The slurry solution is preferably aqueous based slurry solution. The pressure is preferably applied and held substantially constant for a first period at a first pressure and is applied and held substantially constant for a second period, following the first period, at a second pressure higher than the first pressure. 1. A method of packing a chromatography column , comprising:dispersing chromatographic media particles in an aqueous based slurry solution to form a slurry;filling a chromatography column with the chromatographic media particles by introducing the slurry to the column; andapplying a pressure to pack the chromatographic media particles in the chromatography column.2. The method of claim 1 , wherein the aqueous based slurry solution is 100% water claim 1 , or at least 90% claim 1 , or at least 95% claim 1 , or at least 99% claim 1 , by weight water.3. The method of claim 1 , wherein the aqueous based slurry solution contains organic solvent(s) in an amount not more than 100 parts by weight claim 1 , not more than 50 parts by weight claim 1 , or not more than 40 parts by weight claim 1 , or not more than 30 parts by weight claim 1 , or not more than 20 parts by weight claim 1 , or not more than 10 parts by weight claim 1 , or not more than 5 parts by weight claim 1 , or not more than 1 part by weight organic solvent(s) claim 1 , based on 100 parts by weight of water.4. The method of claim 1 , wherein the aqueous based slurry solution further comprises claim 1 , based on 100 parts by weight of water:0-50 parts by weight of surfactant;0-50 parts by weight of electrolyte or salt (other than ionic surfactant);0-100 ...

Access Apparatus and Access Apparatus-Performed Method for Connecting User Device to Network

The present application discloses a method for connecting a user device to a network. The access apparatus may obtain a first IP address from a fixed broadband network and a second IP address from a mobile broadband network, where the first IP address corresponds to a fixed broadband network link, and the second IP address corresponds to a radio link. The access apparatus receives a first packet from a user device, where a source IP address of the first packet is an IP address of the user device. The access apparatus obtains a translated IP address according to a service type of the first packet. The access apparatus obtains a second packet by replacing the source IP address of the first packet with the translated IP address, and sends the second packet to a link corresponding to the translated IP address. 1. A method , comprising:receiving, by an access apparatus, a first packet from a user device, wherein a source IP address of the first packet is an IP address of the user device;obtaining, by the access apparatus, a translated IP address according to a service type of the first packet, wherein the translated IP address is either of a first IP address and a second IP address, wherein the first IP address is obtained by the access apparatus from a fixed broadband network and the first IP address corresponds to a fixed broadband network link, and wherein the second IP address is obtained by the access apparatus from a mobile broadband network and the second IP address corresponds to a radio link;obtaining, by the access apparatus, a second packet by replacing the source IP address of the first packet with the translated IP address; andsending, by the access apparatus, the second packet to a link corresponding to the translated IP address.2. The method according to claim 1 , wherein the service type of the first packet is a first service type or a second service type claim 1 , the first service type is a type of a high priority service determined according to quality ...

Natural Rubber Initial Processing Machinery and Method

An initial processing of natural raw rubber through an initial processing machine, comprising the steps of: (a) providing a coagulated latex which contains water and volatile compositions; (b) dewatering the coagulated latex through a screw-pressing process to remove free water; (c) forming a first pretreated latex material; (d) aging the first pretreated latex material through an aging process to remove water and volatile compositions; and (e) forming a final product of aged latex material. The screw-pressing process makes use of the temperature and pressure increase along the elongated channel structure. The aging process makes use of the further temperature and pressure increase of the rubber materials, together with the screwing effect of the screw-shaft component, the squeezing effect of the nozzle and additional heating at a particular location, which is around the mouthpiece of the nozzle to complete the aging process, which is energy saving, effective and efficient. 1. A drying machine for initial processing of natural raw rubber , comprising:a de-watering machine dewatering a coagulated latex, which contains water and volatile compositions, through a screw-pressing process to remove free water liquid and form a first pretreated latex material in solid form; andan aging machine aging the first pretreated latex material through an aging process in such a manner that water and volatile compositions in gasified formed are removed due to pressure accumulation and subsequent dramatic decrease in pressure to form an aged latex, wherein the first pretreated coagulated latex is transported along an elongated channel structure of the aging machine from a first end to a second end, wherein a pressure along the elongated channel structure is increased and that, at the second end of the elongated channel structure, heat is provided such that the water and volatile compositions in the first pretreated latex material are removed while the aged latex formed has a uniform ...

HIGHLY-INTEGRATED FAIL OPERATIONAL E-POWERTRAIN FOR AUTONOMOUS DRIVING APPLICATION

Embodiments of the present disclosure are directed to using Automotive Safety Integrity Level (ASIL) decomposition and a functional deployment strategy to redundantly distribute functionality across existing controllers. Accordingly, each of a plurality of non-redundant controllers of the vehicle can execute a plurality of functions. The controllers can comprise a vehicle controller and a controller for each of a plurality of different powertrain systems. The plurality of functions can comprise one or more functions for each of the plurality of powertrain systems and each of the functions can execute on multiple controllers. When a failure of one controller occurs, this can be detected either by a controller's build-in internal monitor or by a two-way comparison or three-way voting by external controllers. The functions executing on the failed controller can be transitioned to other controllers based on prior execution of those functions by the other controllers. 1. A method for providing a fail operational powertrain in an electric vehicle , the method comprising:executing, by each of a plurality of controllers of the vehicle, a plurality of functions, the plurality of controllers comprising a vehicle controller and a controller for each of a plurality of different powertrain systems, the plurality of functions comprising one or more functions for each of the plurality of powertrain systems, wherein none of the controllers for the plurality of different powertrain systems are redundant, and wherein each of the plurality of functions executes on a plurality of the plurality of controllers;detecting, by at least one of the plurality of controllers, a failure of a first controller of the plurality of controllers; andin response to detecting the failure of the first controller of the plurality of controllers, transitioning, by the plurality of controllers, the plurality of functions executing on the first controller to one or more second controllers of the plurality of ...

POWER SYSTEMS AND METHODS FOR ELECTRIC VEHICLES

Embodiments include a power device for an electric vehicle. The power device includes a first bus associated with a first voltage, and a second bus associated with a second voltage, different than the first voltage. The power device includes a plurality of switching elements coupled to a first battery, a second battery, the first bus and the second bus. On/off states of the plurality of switching elements control electrical connections to the first bus, the second bus, the first battery and the second battery according to an operation mode. 1. A power device for an electric vehicle , comprising:a first bus associated with a first voltage;a second bus associated with a second voltage, different than the first voltage; anda plurality of switching elements coupled to a first battery, a second battery, the first bus and the second bus, on/off states of the plurality of switching elements controlling electrical connections to the first bus, the second bus, the first battery and the second battery according to an operation mode.2. The power device of claim 1 , wherein the second voltage is less than the first voltage.3. The power device of claim 2 , wherein the first voltage is 800V and the second voltage is 400V.4. The power device of claim 2 , wherein claim 2 , when the operation mode is a charging mode claim 2 , the on/off states of the plurality of switching elements are such that the first battery and the second battery charge with the first voltage from an external power source.5. The power device of claim 4 , wherein claim 4 , when the operation mode is a first driving mode claim 4 , the on/off states of the plurality of switching elements are such that the first battery and the second battery power a powertrain according to the first voltage.6. The power device of claim 5 , wherein claim 5 , when the operation mode is a second driving mode claim 5 , the on/off states of the plurality of switching elements are such that the first battery powers the powertrain ...

BI-LIGAND DRUG CONJUGATE AND USE THEREOF

The present disclosure discloses a conjugate compound or a pharmaceutically acceptable salt thereof, comprising a payload and two targeting molecules. Further disclosed herein is a pharmaceutical composition, comprising the conjugate compound or the pharmaceutically acceptable salt thereof. The present disclosure additionally relates to a method for delivering a payload to a subject in need thereof, and a method for treating a disease, wherein the methods comprise administering to the subject a therapeutically effective amount of the conjugate compound or the pharmaceutically acceptable salt thereof, or the pharmaceutical composition as disclosed herein. 1. A conjugate compound or a pharmaceutically acceptable salt thereof , comprising a payload and two targeting molecules , wherein the two targeting molecules are a synergistic molecule moiety and a prostate-specific membrane antigen ligand moiety , respectively.611-. (canceled)12. The conjugate compound or the pharmaceutically acceptable salt thereof according to claim 1 , wherein the synergistic molecule binds to a molecule selected from the group consisting of FOLR1 claim 1 , TRPV6 claim 1 , FOLH1 (PMSA) claim 1 , GNRHR claim 1 , Her2 claim 1 , Trop2 claim 1 , Her3 claim 1 , NECTIN4 claim 1 , LRP1 claim 1 , GLUT1 claim 1 , EGFR1 claim 1 , AXL claim 1 , CA9 claim 1 , CD44 claim 1 , Claudin18.2 claim 1 , APN claim 1 , DLL3 claim 1 , CEACAM5 claim 1 , FZD10 claim 1 , TFRC claim 1 , MET claim 1 , IGFR1 claim 1 , SSTR2 claim 1 , CCKBR claim 1 , LFA1 claim 1 , ICAM claim 1 , GPR87 claim 1 , GM-CSF claim 1 , GM-CSFR claim 1 , TIM3 claim 1 , TLR family claim 1 , CD40 claim 1 , CD40L claim 1 , OX40 claim 1 , OX40L claim 1 , GITRL claim 1 , GITR claim 1 , 4-BBL claim 1 , 4-1BB claim 1 , CD70 claim 1 , CD27 claim 1 , ICOSL claim 1 , ICOS claim 1 , HHLA2 claim 1 , CD28 claim 1 , CD86/80 claim 1 , CD28 claim 1 , MHCII antigen claim 1 , TCR claim 1 , CTLA-4 claim 1 , CD155 claim 1 , CD122 claim 1 , CD113 claim 1 , IGIT claim 1 ...

5,6-FUSED-BICYCLIC COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES

The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof; (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition. 2. The compound according to or a pharmaceutically acceptable salt thereof claim 1 , wherein Ring A is phenyl.3. The compound according to or a pharmaceutically acceptable salt thereof claim 1 , wherein Ring A is pyridinyl.5. The compound according to or a pharmaceutically acceptable salt thereof claim 1 , wherein Ris azetidinyl claim 1 , which is unsubstituted or substituted by 1 to 2 substituents independently selected from halogen and Calkyl; or two substituents on the same ring atom of the azetidinyl claim 1 , together with the ring atom to which both are attached claim 1 , form a spiro cyclopropyl or spiro tetrahydrofuranyl attached to the azetidinyl ring.7. The compound according to or a pharmaceutically acceptable salt thereof claim 1 , wherein Ris halo and n is 1.8. The compound according to or a pharmaceutically acceptable salt thereof claim 7 , wherein Ris fluoro.10. The compound according to or a pharmaceutically acceptable salt thereof claim 1 , wherein Ris —NRR;{'sup': '6a', 'sub': '1-4', 'Ris hydrogen or Calkyl;'}{'sup': 6b', '6a', '6b, 'sub': 1-4', '1-4', '1-4, 'Ris hydrogen, Calkoxycarbonyl or Calkyl that is unsubstituted or substituted by Calkoxy; or Rand Rtogether with the nitrogen atom to which both are attached form a 4- to 6-membered heterocycloalkyl optionally comprising 1 to 2 additional heteroatoms independently selected from N, O and S as ring atoms;'}{'sub': 1-4', '1-4', '1-4', '1-4', '1-4, 'wherein the 4- to 6-membered heterocycloalkyl is unsubstituted or substituted by 1 to 2 substituents independently selected from halogen, cyano, hydroxyl, Calkyl, Chaloalkyl, CalkoxyCalkyl, Calkoxy, and oxo; or two substituents on the same or ...

VEHICLE PATH-PLANNER MONITOR AND CONTROLLER

Systems of an autonomous vehicle and the operations thereof are provided. Autonomous vehicles may rely on data inputs, processes, and output commands. Errors due to translation errors, failed or faulty equipment, connections, and other components may cause a dynamic vehicle path to approach a dynamic safe zone. If so, a warning message may be sent and processed by the motion control system, when the vehicle is responding to commands correctly, or actuator control, when the vehicle is not responding to commands correctly. Should the vehicle's path approach the safe zone, a failure message is sent to the appropriate system for mitigation. 1. An autonomous driving system , comprising:a processor, the processor further comprising circuitry and a memory;a sensor, in communication with the processor;an actuator control programmed to receive a motion control command and convert the motion control command into an actuator command;an actuator configured, in response to receiving an actuator command, to execute an operation controlling an aspect of locomotion for the vehicle and further provide an actuator feedback signal;a motion control system programmed to determine a planned path and provide motion control commands to the actuator to cause the vehicle to traverse the planned path; and access a safety envelope for the vehicle;', 'receive indicia of an observed path from the vehicle from the sensor;', 'determine the observed path has breached the safety envelope;', 'in response to determining the safety envelope has been breached, determine whether the actuator feedback is divergent from the motion control commands;', 'in response to determining the actuator feedback is divergent from the motion control command, process a failure in accord with an actuator failure; and, 'wherein the processor, in communication with the actuator control and the motion control system, is programmed towherein processing the failure comprises executing a mitigating action to mitigate the ...

PROVIDING A SCENT WHILE A USER INTERACTS WITH AN ELECTRONIC MEDIA PROVIDING DEVICE

A request to open electronic media on the electronic media providing device is detected. A scent is sprayed in response to the detecting of the request to open the electronic media. 1. A method of providing a scent while a user interacts with an electronic media providing device , the method comprising:detecting a request to open electronic media on the electronic media providing device; andspraying a scent in response to the detecting of the request to open the electronic media.2. The method of claim 1 , wherein the media is selected from a group consisting of an electronic book and an electronic game.3. The method of claim 1 , wherein the method further comprises:associating different types of scents with different types of media; anddetermining the scent from a plurality of scents based on a type of the media that is opened.4. The method as recited by claim 3 , wherein the method further comprises:associating different categories of media with each of the scents;determining a category of the media; andselecting the scent from the plurality of scents based on the category.5. The method as recited by claim 4 , wherein the method further comprises:determining the category of the media based on at least one word in a title of the media.6. The method as recited by claim 1 , wherein the method further comprises:repeatedly spraying the scent until an event occurs, wherein the event is selected from a group consisting of exiting the media, marking the media as complete, completing a first chapter of the media, and completing a subset of the media.7. A system of providing a scent while a user interacts with an electronic media providing device claim 1 , the system comprising:detect requesting media logic that detects a request to open electronic media on the electronic media providing device;an external device with a scent tank; andscent spraying logic that sprays a scent from the scent tank in response to the detecting of the request to open the media.8. The system of ...

Chromatographic material and method for preparation thereof

A chromatographic material comprising a zwitterionic ligand covalently bound to a substrate, the ligand preferably has a formula II: wherein R 1 , R 2 , R 3 are independently selected from an oxygen atom that is configured to connect to a substrate atom in the substrate, an oxygen atom that is configured to connect to a silicon atom of an adjacent ligand, a hydroxyl group, a halogen atom, an alkoxy group, a dialkylamino group, an acyl group, an alkyl group, or an aryl group; L 1 , L 2 and L 3 are independently hydrophobic moieties; each containing 2 to 30 carbon atoms, wherein there are at least 10 carbon atoms in the combined chain lengths of L 1 , L 2 and L 3 ; X is an O atom, S atom, amide group or sulfonamide group; n is 0 or 1; R 4 , R 5 are independently selected from a hydrogen atom or a hydrocarbon moiety containing 1 to 20 carbon atoms; and R f is a negatively charged moiety comprising a sulfonic, carboxylic, or phosphonic functional group.

ADVERSARIAL TRAINING OF MACHINE LEARNING MODELS

This document relates to training of machine learning models such as neural networks. One example method involves providing a machine learning model having one or more layers and associated parameters and performing a pretraining stage on the parameters of the machine learning model to obtain pretrained parameters. The example method also involves performing a tuning stage on the machine learning model by using labeled training samples to tune the pretrained parameters. The tuning stage can include performing noise adjustment of the labeled training examples to obtain noise-adjusted training samples. The tuning stage can also include adjusting the pretrained parameters based at least on the labeled training examples and the noise-adjusted training examples to obtain adapted parameters. The example method can also include outputting a tuned machine learning model having the adapted parameters. 1. A method performed on a computing device , the method comprising:providing a machine learning model having one or more layers and associated parameters;performing a pretraining stage on the parameters of the machine learning model to obtain pretrained parameters; performing noise adjustment of the labeled training samples to obtain noise-adjusted training samples, and', 'adjusting the pretrained parameters based at least on the labeled training samples and the noise-adjusted training samples to obtain adapted parameters; and, 'performing a tuning stage on the machine learning model by using labeled training samples to tune the pretrained parameters, the tuning stage includingoutputting a tuned machine learning model having the adapted parameters.2. The method of claim 1 , wherein the adjusting comprises computing a loss function comprising:a first term that is proportional to a difference between predictions of the machine learning model and labels of the labeled training samples, anda second term that is proportional to a difference between output of the machine learning ...

OPERATING AN ELECTRONIC PERSONAL DISPLAY USING EYE MOVEMENT TRACKING

An electronic personal display is operated using a camera of an electronic personal display to track a user's eye movement. Based on the tracking, the user's gaze is correlated with a selectable region of the electronic personal display. Responsible to the gaze being correlated with the selectable region for at least a predetermined time, an operation of the electronic personal display is implemented wherein the operation is associated with the selectable region. Various embodiments do not require any external device, such as eye wear, as a part of tracking the user's eye movement. 1. A method of operating an electronic personal display , the method comprising:tracking eye movement of a user of an electronic personal display with a camera of the electronic personal display;based on the tracking, correlating a gaze of the user with a selectable region of the electronic personal display; andresponsive to the gaze being correlated with the selectable region for at least a predetermined time, implementing an operation of the electronic personal display which is associated with the selectable region.2. The method as recited by claim 1 , wherein the method further comprises executing a training routine on said electronic personal display to model the tracking and correlation with respect to the electronic personal display.3. The method as recited by claim 1 , wherein the implementation of the operation further comprises:implementing the operation selected from a group consisting of opening a menu, selecting an option from a menu, opening an e-book for display on the electronic personal display, closing an e-book that is currently displayed on the electronic personal display, scrolling through pages of an e-book currently displayed on the electronic personal display, turning a page of an e-book currently displayed on the electronic personal display, adding a bookmark to an e-book that is displayed on the electronic personal display, turning off the electronic personal ...

Resilient high-voltage interlock loop

Systems of an electrical vehicle and the operations thereof are provided. High-voltage interlock (HVIL) determines if a high-voltage system, such as a power source (e.g., vehicle battery), a load (e.g., vehicle motor), and conductors therebetween, have been properly connected. If not, battery contactor is not allowed to be closed or, if already closed, opened. A redundant HVIL system is provided to mitigate the false positives associated with an HVIL component failure.

NANOMETER SIZE CHEMICAL MODIFIED MATERIALS AND USES

Ligand compositions and stationary phases comprising polyhedral oligomeric silsesquioxane moieties are incorporated in to chromatographic stationary phases, and these phases are incorporated into chromatography devices, such as columns. The compositions and devices are of use to separate molecular mixtures. 1. A method of separating analytes in a liquid sample , the method comprising: a solid support having an exterior surface; and', 'a ligand comprising a polyhedral oligomeric silsesquioxane moiety covalently, 'flowing the liquid sample through a chromatography column configured for use in liquid chromatography, the chromatography column containing therein a composition, the composition comprisingbound to the exterior surface, wherein the polyhedral oligomeric silsesquioxane moiety is not a cross-linker.2. The method of claim 1 , wherein the liquid sample comprises anions claim 1 , cations and uncharged molecules claim 1 , each essentially retained by the composition.3. The method of claim 1 , wherein the polyhedral oligomeric silsesquioxane moiety is covalently bound to the exterior surface through a linker covalently bound to both the polyhedral oligomeric silsesquioxane moiety and the exterior surface.4. The method of claim 3 , wherein the linker comprises at least 4 carbon atoms in sequence.5. The method of claim 3 , wherein the linker comprises at least one heteroatom selected from N claim 3 , O claim 3 , S and a combination thereof.6. The method of claim 1 , wherein the solid support is a particle.7. The method of claim 1 , wherein the solid support comprises a flow-through monolith.8. The method of claim 1 , wherein the solid support is in particulate form claim 1 , and wherein multiple support particles are disposed in a packed bed.9. The method of claim 1 , wherein the solid support comprises a member selected from silica claim 1 , alumina claim 1 , titania claim 1 , zirconia claim 1 , and combinations thereof.10. The method of claim 1 , wherein the solid ...

COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS

The invention provides compounds and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some embodiments, the invention provides methods for using such compounds to treat, ameliorate or prevent diseases or disorders that involve abnormal activation of c-kit or c-kit and PDGFR (PDGFRα, PDGFRβ) kinases. 3. The method of claim 1 , wherein Ris selected from —CHand F.4. The method of claim 3 , wherein Ris —CH.5. The method of claim 1 , wherein each Ris independently selected from H claim 1 , F and —CH.6. The method of claim 5 , wherein each Ris H.7. The method of claim 1 , wherein Ris selected from an unsubstituted 4-6 membered heterocycloalkyl with 1-2 heteroatoms independently selected from N and O claim 1 , a piperidinone claim 1 , a oxazolidin-2-one claim 1 , pyrrolidinone claim 1 , a pyrrolidin-2-one and a substituted 4-6 membered heterocycloalkyl with 1-2 heteroatoms independently selected from N and O claim 1 ,{'sup': 3', '4', '4', '4', '7', '5', '9', '4', '9', '4', '4', '4', '4', '4', '9', '4', '8', '9', '8', '4', '7', '8', '4', '4', '9', '4', '9', '4, 'sub': 1', '6', '1', '6', '2', 'n', '2', 'n', '2', '2', 'n', '2', 'n', '2', '2', '2', '2', '2', '2', '2', '2', 'n', '2', '2', 'n', '1, 'wherein the substituted 4-6 membered heterocycloalkyl of Ris substituted with 1-4 substituents independently selected from C-Calkyl, halo, —CN, C-Chaloalkyl, —OR, —C(═O)OR, —C(═O)R, —C(═O)R, —C(═O)OR, —(CR)OR, —C(═O)O(CR)OR, —C(═O)NR, —NRC(═O)OR, —NRC(═O)(CR)OR, —R, —(CR)R, —S(═O)R, —S(═O)R, —S(═O)R, —S(═O)N(R), —S(═O)NHC(═O)OR, —S(═O)(CR)OR, —S(═O)(CR)C(═O)ORand a Calkyl bridge.'}8. The method of claim 7 , wherein each Ris independently selected from H claim 7 , methyl claim 7 , ethyl claim 7 , propyl claim 7 , butyl claim 7 , i-propyl and t-butyl.9. The method of claim 7 , wherein each Ris cyclopropyl ...

HEARING AID WITH EAR EEG RECORDING

A hearing aid includes a plurality of electrode units, where each of the plurality of electrode units includes an electrode configured to provide an electrical stimulation to a user of the hearing aid and/or to measure a bio response signal of the user; a plurality of electrode channel circuits, where each of the plurality of electrode channel circuits includes: an operational amplifier comprising a first input terminal configured to receive the bio response signal and provide an amplified bio response signal, and the operational amplifier includes a first load input; a first DC offset unit configured to reduce the impact of DC offset in the electrode channel circuit of the plurality of electrode channel circuits by receiving a part of the amplified bio response signal and converting it to a feedback current signal which is transmitted to the first load input for providing balanced drain currents in the operational amplifier. 1. A hearing aid comprising;a plurality of electrode units, where each of the plurality of electrode units includes an electrode configured to provide an electrical stimulation to a user of the hearing aid and/or to measure a bio response signal of the user; an operational amplifier comprising a first input terminal configured to receive the bio response signal and provide an amplified bio response signal, and the operational amplifier includes a first load input;', 'a first DC offset unit configured to reduce the impact of DC offset in the electrode channel circuit of the plurality of electrode channel circuits by receiving a part of the amplified bio response signal and converting it to a feedback current signal which is transmitted to the first load input for providing balanced drain currents in the operational amplifier., 'a plurality of electrode channel circuits, where each of the plurality of electrode channel circuits includes2. A hearing aid according to claim 1 , wherein each of the plurality of electrode channel circuits includes a ...

MULTI-STANDARD PERFORMANCE RECONFIGURABLE I/Q ORTHOGONAL CARRIER GENERATOR

The present disclosure discloses a multi-standard performance reconfigurable I/Q orthogonal carrier generator. The generator may implement a continuously covered I/Q carrier output of 0.1-5 GHz and continuously covered differential signal outputs of 5-10 GHz and 1.5-3 GHz by means of reasonable frequency assignment; also, carrier signals under various frequencies with different loop bandwidths, different phase noises, different power consumption levels and different locking times can be generated by configuring a programmable charge pump (), a loop filter () parameter, a multi-path voltage-controlled oscillator () and a first multiplexer () corresponding thereto, a five-stage-division-by-two frequency division link () and a corresponding second multiplexer () and third multiplexer (), so as to implement generation of a multi-standard performance reconfigurable I/Q orthogonal carrier. 1. A multi-standard performance reconfigurable I/Q orthogonal carrier generator , comprising:a phase frequency detector for comparing a frequency and a phase of an input reference signal with a frequency and a phase of an output signal of a programmable multi-mode frequency divider;a programmable charge pump, which is controlled by an output signal of the phase frequency detector for generating a charging/discharging current, so as to charge/discharge a loop filter to change an output voltage of the loop filter;the loop filter for converting the charging/discharging current from the programmable charge pump into an analog voltage for controlling a multi-path voltage controlled oscillator;the multi-path voltage controlled oscillator, which is controlled by the analog voltage to generate a locking frequency range of a phase locked loop as required;a first multiplexer for selecting a path for an output signal of the multi-path voltage controlled oscillator, so as to decide which voltage controlled oscillator provides an oscillation frequency;a division-by-two frequency pre-divider, for ...

Two Cameras Vehicle Recognition System and Collection Method

This invention relates to the field of highway vehicle toll collection system and vehicle license plate recognition technology, in particular involving two cameras vehicle recognition system and collection method. It is composed of the door entry system and the photographing recognition system based on an ETC system, wherein the photographing recognition system comprises a main camera and an auxiliary camera, and the main camera and the auxiliary camera are installed from front to back respectively on two upright posts, and the data is transmitted to the computer of the toll booth through the two complementary cameras. This invention can accurately replace the existing high-speed ETC RFID (radio frequency identification) device and realize the zero-cost during the journey through the accurate recognition of the license plate and the automatic recognition and conversion of the vehicle license plate number image into the digital signal. 1. The two cameras vehicle recognition system comprising the door entry system and the photographing recognition system based on an ETC system , which characterized by the photographing recognition system comprising the main camera and the auxiliary camera , and the main camera and the auxiliary camera are installed from front to back respectively on two upright posts , and the data is transmitted to the computer of the toll booth through the two complementary cameras , data analysis and judgment are performed by the computer for further controlling the door entry system of the toll collection system.2. A vehicle recognition collection method claim 1 , which characterized by vehicle recognition collection system based on claim 1 , the vehicle recognition collection method includes the following steps:(1) The vehicle enters the ETC lane, and the photographing recognition system photographs the license plate through two cameras, and transmits the license plate number to the system computer;(2) Firstly, recognize the license plate by the ...

EPOXY CHEMISTRY DERIVED MATERIALS AS REVERSED-PHASE AND HYDROPHOBIC INTERACTION CHROMATOGRAPHY MEDIA, METHOD FOR THEIR SYNTHESIS AND USE

This invention provides aqueous-compatible, polar-embedded reversed-phase stationary phase compositions, devices and systems comprising the stationary phases as well as methods of producing these compositions using epoxide ring-opening reactions. Also provided are methods of using the stationary phases of the invention in separations. 2. The compound of claim 1 , wherein{'sup': 1', '2', '3', '10', '12', '12, 'sub': '2', 'R, Rand Rare selected independently from the group consisting of OR, OC(O)R, OS(O)R, unsubstituted alkyl and a bond to said substrate,'} [{'sup': 10', '11, 'each Rand each Ris selected independently from the group consisting of H, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocycloalkyl and a bond to said substrate;'}, {'sup': '12', 'each Ris selected independently from the group consisting of substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, and substituted or unsubstituted heterocycloalkyl;'}, {'sup': '1', 'sub': '3', 'Lis Cunsubstituted alkyl; and'}, {'sup': '2', 'sub': 1', '8, 'Lis C-Cunsubstituted alkyl.'}], 'wherein'}3. The compound of claim 1 , wherein{'sup': '20', 'Ris selected from the group consisting of H, substituted or unsubstituted phenyl, unsubstituted linear or branched alkyl, and alkyl substituted with substituted or unsubstituted phenyl;'}{'sup': '21', 'Ris selected from the group consisting of H, substituted or unsubstituted phenyl, and unsubstituted linear or branched alkyl, and alkyl substituted with substituted or unsubstituted phenyl,'}{'sup': 1', '20', '2', '21', '20', '21, 'with the proviso that at least one of XRor XRis OH, and both Rand Rcannot both be H;'}{'sup': 1', '2', '3', '10', '12', '12, 'sub': '2', 'R, Rand Rare selected independently from the group consisting of OR, OC(O) ...

Epoxy chemistry derived materials as mixed mode chromatography media, method for their synthesis and use

This invention provides mixed-mode stationary phase compositions, devices and systems comprising the stationary phases as well as methods of producing these compositions using epoxide ring-opening reactions. Also provided are methods of using the stationary phases of the invention in separations.

CHROMATOGRAPHIC MATERIAL HAVING IMPROVED PH STABILITY, METHOD FOR PREPARATION THEREOF AND USES THEREOF

A chromatographic material including a substrate having a surface and having a polymeric layer covalently bound to the surface; the polymeric layer comprising polymer molecules covalently attached to the surface of the substrate, each polymer molecule being attached to the surface via multiple siloxane bonds and each polymer molecule being connected to one or more functionalizing compounds that each comprise a functional group, wherein the polymeric layer is formed by covalently attaching polymer molecules to the surface of the substrate via multiple siloxane bonds, each polymer molecule containing multiple first reactive groups, and reacting the first reactive groups of the attached polymer molecules with at least one functionalizing compound that comprises a second reactive group that is reactive with the first reactive groups and that further comprises a functional group. Preferred conditions of reacting the polymer with the substrate include elevated temperature and reduced pressure. 1. A method of separating a sample , the method comprising: a substrate having a surface and the substrate having a polymeric layer covalently bound to the surface;', 'the polymeric layer comprising polymer molecules covalently attached to the surface of the substrate, each polymer molecule being attached to the surface via multiple siloxane bonds and each polymer molecule being connected to one or more functionalizing compounds that each comprise a functional group, wherein the functional group comprises C14-C22 alkyl, each polymer molecule containing multiple first reactive groups and multiple silyl groups,', 'wherein the polymeric layer is formed by covalently attaching the polymer molecules to the surface of the substrate via the multiple silyl groups, and reacting the first reactive groups of the attached polymer molecules with the one or more functionalizing compounds, wherein the one or more functionalizing compounds each comprise a second reactive group, wherein the second ...

MAIN BUS-BAR, A BRANCH BUS-BAR, A TRANSFER CONNECTOR AND A BUS-BAR ASSEMBLY

Embodiments of the present disclosure disclose a main bus-bar. The main bus-bar consists of a first elongated flat portion and a second elongated flat portion. A longitudinal side of the first elongated flat portion and a longitudinal side of the second elongated flat portion are arranged to be joined with each other at a predetermined angle. The thickness of each of said the first elongated flat portion and the second elongated flat portion is non-uniform. With embodiments of the present disclosure, the skin effect and proximity effect caused by current carried in the main bus-bar can be reduced greatly. Embodiments of the present disclosure also disclose a transfer connector, a bus-bar assembly and a bus-bar system. 1. A main bus-bar comprising a first elongated flat portion and a second elongated flat portion , wherein a longitudinal side of said first elongated flat portion and a longitudinal side of said second elongated flat portion are arranged to be joined with each other at a predetermined angle (α) , and a thickness of each of said first elongated flat portion and said second elongated flat portion is non-uniform.2. The main bus-bar according to claim 1 , wherein the thickness of each of said first elongated flat portion and said second elongated flat portion is gradually increased or decreased away from a joint area of said first elongated flat portion and said second elongated flat portion.3. The main bus-bar according to claim 1 , wherein a width of said first elongated flat portion is equal to that of said second elongated flat portion.4. The main bus-bar according to claim 1 , wherein the other longitudinal side of at least one of the first elongated flat portion and the second elongated flat portion claim 1 , opposite to the joint area claim 1 , is provided with a rounded flange claim 1 , a thickness of which is wider than that of the rest of the respective elongated flat portion.5. The main bus-bar according to claim 4 , wherein the rounded flange ...

MULTI-LIGAND DRUG CONJUGATES AND USES THEREOF

A conjugate compounds or pharmaceutically acceptable salt thereof, comprises a payload and two or more kinds of cell-interacting molecules. The cell-interacting molecules are ligands capable of specifically binding to a cell surface receptor. A method of treating diseases, comprises delivering a payload to a subject. 1. A conjugate compound or a pharmaceutically acceptable salt thereof , comprising a payload and two or more kinds of cell-interacting molecules , wherein the payload is conjugated with at least one of the cell-interacting molecules.2. The conjugate compound of claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein the payload is conjugated with at least one of the cell-interacting molecules via a linker.3. The conjugate compound of claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein at least one of the cell-interacting molecules is a ligand capable of specifically binding to a cell surface receptor.4. (canceled)5. The conjugate compound of claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein at least one of the cell-interacting molecules is an endocytosis molecule capable of mediating endocytosis.6. The conjugate compound of claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein the two or more kinds of cell-interacting molecules comprise a first ligand capable of specifically binding to a first cell surface receptor claim 1 , and a second ligand capable of specifically binding to a second cell surface receptor.7. The conjugate compound of claim 6 , or a pharmaceutically acceptable salt thereof claim 6 , wherein the payload is conjugated with the first ligand claim 6 , and the first ligand is conjugated with the second ligand.8. The conjugate compound of claim 7 , or a pharmaceutically acceptable salt thereof claim 7 , wherein the first ligand is conjugated with the second ligand via a spacer.910-. (canceled)11. The conjugate compound of claim 6 , or a pharmaceutically ...

TECHNOLOGIES FOR ADAPTIVE PROCESSING OF MULTIPLE BUFFERS

Technologies for adaptive processing of multiple buffers is disclosed. A compute device may establish a buffer queue to which applications can submit buffers to be processed, such as by hashing the submitted buffers. The compute device monitors the buffer queue and determines an efficient way of processing the buffer queue based on the number of buffers present. The compute device may process the buffers serially with a single processor core of the compute device or may process the buffers in parallel with single-instruction, multiple data (SIMD) instructions. The compute device may determine which method to use based on a comparison of the throughput of serially processing the buffers as compared to parallel processing the buffers, which may depend on the number of buffers in the buffer queue. 125-. (canceled)26. A compute device for adaptive processing of multiple buffers , the compute device comprising:a processor comprising one or more processor cores;a buffer queue manager to determine a number of buffers in a buffer queue; anda buffer processor to:determine, based on the number of buffers, whether to process the buffer queue in parallel in a single processor core of the one or more processor cores with single instruction, multiple data (SIMD) instructions;process, if the compute device is to process the buffer queue in parallel in the single processor core, two or more buffers in the buffer queue with the SIMD instructions; andserially process, if the compute device is not to process the buffer queue in parallel with the single processor core, one or more buffers in the buffer queue.27. The compute device of claim 26 , wherein the buffer queue manager is further to determine an algorithm to be applied to buffers in the buffer queue claim 26 , and wherein the buffer processor is further to:determine a throughput per buffer of the algorithm when processed in parallel in the single processor core; anddetermine a throughput per buffer of the algorithm when ...

CONFIGURABLE DEVICE INTERFACE

Examples described herein relate to an apparatus comprising: a descriptor format translator accessible to a driver. In some examples, the driver and descriptor format translator share access to transmit and receive descriptors. In some examples, based on a format of a descriptor associated with a device differing from a second format of descriptor associated with the driver, the descriptor format translator is to: perform a translation of the descriptor from the format to the second format and store the translated descriptor in the second format for access by the device. In some examples, the device is to access the translated descriptor; the device is to modify content of the translated descriptor to identify at least one work request; and the descriptor format translator is to translate the modified translated descriptor into the format and store the translated modified translated descriptor for access by the driver. 1. A method comprising:providing a device with access to a descriptor, wherein the descriptor comprises a first format of an organization of fields and field sizes; performing a translation of the descriptor from the first format to the second format and', 'storing the translated descriptor in the second format for access by the second device; and, 'based on the first format of the descriptor differing from a second format of descriptor associated with a second devicebased on the first format of the descriptor matching the second format of descriptor associated with the second device, storing the descriptor for access by the second device.2. The method of claim 1 , wherein the first format is associated with a driver and comprising: performing a translation of the second descriptor from the second format to the first format associated with the driver and', 'storing the translated second descriptor for access by the driver., 'based on the second device providing a second descriptor of the second format3. The method of claim 1 , comprising:the second ...

ML USING N-GRAM INDUCED INPUT REPRESENTATION

Generally discussed herein are devices, systems, and methods for generating an embedding that is both local string dependent and global string dependent. The generated embedding can improve machine learning (ML) model performance. A method can include converting a string of words to a series of tokens, generating a local string-dependent embedding of each token of the series of tokens, generating a global string-dependent embedding of each token of the series of tokens, combining the local string dependent embedding the global string dependent embedding to generate an n-gram induced embedding of each token of the series of tokens, obtaining a masked language model (MLM) previously trained to generate a masked word prediction, and executing the MLM based on the n-gram induced embedding of each token to generate the masked word prediction. 1. A system comprising:processing circuitry; converting a string of words to a series of tokens;', 'generating a local string-dependent embedding of each token of the series of tokens;', 'generating a global string-dependent embedding of each token of the series of tokens;', 'combining the local string dependent embedding the global string dependent embedding to generate an n-gram induced embedding of each token of the series of tokens;', 'obtaining a masked language model (MLM) previously trained to generate a masked word prediction; and', 'executing the MLM based on the n-gram induced embedding of each token to generate the masked word prediction., 'a memory coupled to the processing circuitry, the memory including a program stored thereon that, when executed by the processing circuitry, cause the processing circuitry to perform operations comprising2. The system of claim 1 , wherein generating the local string-dependent embedding of each token includes generating an n-gram of a window of tokens of the series of tokens.3. The system of claim 2 , wherein generating the local string-dependent embedding of each window of tokens ...

CHROMATOGRAPHIC MATERIAL AND METHODS FOR THE SYNTHESIS THEREOF

A particulate material for chromatographic use comprising silica particles is provided having a skeleton structure containing silsesquioxane cage moieties. The material is useful as a chromatographic material, for example in HPLC. The silica particles may be hybrid organo-silica particles wherein the silsesquioxane moieties comprise a cage structure having silicon atoms positioned at corners of the cage wherein one or more silicon atoms positioned at the corners of the cage carry an organic group. A preferred method of preparing the particulate material comprises hydrolysing a silsesquioxane as a co-component of a hydrolysis mixture, especially in a Stöber or modified Stöber process. 1. A particulate material for chromatographic use comprising silica particles having a skeleton structure containing silsesquioxane moieties having a cage structure.2. A particulate material as claimed in wherein the silica particles are hybrid organo-silica particles wherein the silsesquioxane moieties comprise a cage structure having silicon atoms positioned at corners of the cage wherein one or more silicon atoms positioned at the corners of the cage carry an organic group.3. A particulate material as claimed in wherein the organic group is a hydrocarbon group.4. A particulate material as claimed in wherein the hydrocarbon group is an alkyl group or aryl group.5. A particulate material as claimed in wherein the cage structure has a missing corner.6. A particulate material as claimed in wherein the cage structure has one or more missing corners and one or more missing edges.7. A particulate material as claimed in wherein the cage structure comprises seven or six corner silicon atoms and each corner silicon atom carries an organic group.8. A particulate material as claimed in wherein the cage structure comprises seven corner silicon atoms and each corner silicon atom carries an organic group.9. A particulate material as claimed in wherein the hybrid organo silica particles have a ...

SOUND DEVICE AND ELETRONIC DEVICE USING SOUND DEVICE

The present invention provides a sound device and an electronic device using the sound device. The sound device includes a housing with an accommodating space, a sound unit accommodated in the housing and a control device arranged outside the housing. The sound unit divides the accommodating space into a front cavity and a rear cavity, and a through hole is arranged in a position of the housing corresponding to the rear cavity. The control device includes a sealing member sealing the through hole. When the control device presses the sealing member against the housing and the through hole is sealed by the sealing member, the sound device is in a first sound mode. When the control device disengages the sealing member from the housing and the through hole is not sealed by the sealing member, the sound device is in a second sound mode. 1. A sound device , comprising a housing with an accommodating space , a sound unit accommodated in the housing and a control device arranged outside the housing , wherein the sound unit divides the accommodating space into a front cavity and a rear cavity , a through hole is arranged in a position of the housing corresponding to the rear cavity , and the control device comprises a sealing member sealing the through hole , wherein:when the control device presses the sealing member against the housing and the through hole is sealed by the sealing member, the sound device is in a first sound mode; andwhen the control device disengages the sealing member from the housing and the through hole is not sealed by the sealing member, the sound device is in a second sound mode.2. The sound device according to claim 1 , wherein the control device further comprises a transmission rod and a motor controlling the transmission rod to extend and retract claim 1 , and the sealing member is arranged at a tail end of the transmission rod.3. The sound device according to claim 1 , wherein the sealing member is made of foam.4. An electronic device claim 1 , ...

METHOD AND SYSTEM FOR TRANSITIONING TO PRIVATE E-READING MODE

A method executed in a processor of a computing device for providing an e-book privacy mode is provided. The method includes tracking eye movement of a first user of an electronic personal display with a camera of the electronic personal display, based on the tracking, correlating a gaze of the first user with a selectable region of the electronic personal display, identifying eye movement of a second user proximate the electronic personal display with the camera of the electronic personal display and responsive to the identification of eye movement of the second user, implementing a privacy operation of the electronic personal display which is associated with the selectable region. 1. A method of operating an electronic personal display , the method comprising:tracking eye movement of a first user of an electronic personal display with a camera of the electronic personal display;based on the tracking, correlating a gaze of the first user with a selectable region of the electronic personal display;identifying eye movement of a second user proximate the electronic personal display with the camera of the electronic personal display;responsive to the identification of eye movement of the second user, implementing a privacy operation of the electronic personal display which is associated with the selectable region.2. The method as recited by wherein the privacy operation includes:closing said selectable region.3. The method as recited by wherein the privacy operation includes:transitioning from a current page to a home page.4. The method as recited by claim 1 , wherein the implementation of the privacy operation further comprises:implementing the operation selected from a group consisting of opening a menu, selecting an option from a menu, opening an e-book for display on the electronic personal display, closing an e-book that is currently displayed on the electronic personal display, scrolling through pages of an e-book currently displayed on the electronic personal ...

ASSEMBLY COMPRISING COAXIAL CABLE AND RIGHT-ANGLED COAXIAL CONNECTOR AND MANUFACTURING METHOD THEREOF

An assembly includes a right-angled coaxial connector, a first coaxial cable and a second coaxial cable. The right-angled coaxial connector includes a first component and a second component connected to a first coaxial cable and a second coaxial cable respectively. The inner conductor and the outer conductor of the first coaxial cable and the first inner conductor and the first outer conductor of the first component, the inner conductor and the outer conductor of the second coaxial cable and the second inner conductor and the second outer conductor of the second component, as well as the first inner conductor and the first outer conductor of the first component and the second inner conductor and the second outer conductor of the second component are permanently connected in a single welding procedure through a first soldering element, a second soldering element and a third soldering element, respectively. 1. An assembly comprising a right-angled coaxial connector , a first coaxial cable and a second coaxial cable , and the right-angled coaxial connector comprising:a first component provided with a first length direction and a first end along the first length direction, the first component being further provided with a first inner conductor and a first outer conductor, and the ends of the first inner conductor and the first outer conductor that are distal to the first end being electrically connected with an inner conductor and an outer conductor of the first coaxial cable respectively through a first soldering element;a second component provided with a second length direction substantially perpendicular to the first length direction and a second end along the second length direction, the second component being further provided with a second inner conductor and a second outer conductor, and the ends of the second inner conductor and the second outer conductor that are distal to the second end being electrically connected with an inner conductor and an outer conductor ...

Sound Generator

The invention provides a sound generator having a frame, a vibration system and a magnetic circuit system carried by the frame. The vibration system includes a diaphragm, a coil and an elastic support assembly. The diaphragm includes a first suspension ring fixed with the frame, a first dome at a center of the first suspension ring, and a second dome stacked on the first dome. The first dome includes a main body, a first wall, and a second wall extending perpendicularly from the first wall for connecting to the coil via the first wall. The first wall is connected to a side surface of the coil. The first wall and the second wall are used for elastically suspending the coil below the diaphragm. Thus, the sound generator has improved high frequency performance. 2. The sound generator as described in claim 1 , wherein the elastic support assemblies enclose a hollow area claim 1 , the voice coil is far away from one end of the first dome and located within the hollow area.3. The sound generator as described in claim 2 , wherein each of the first wall and the second wall comprises two piece provided spaced apart from each other on the two opposite sides of the voice coil.4. The sound generator as described in claim 3 , wherein each second wall comprises a first section spaced apart from the voice coil and a second section extending from the two opposite ends of the first section to the two first walls respectively claim 3 , the first section is connected with the elastic support assembly claim 3 , the two second sections of the same second wall are connected with the two first walls respectively.5. The sound generator as described in claim 4 , wherein the voice coil is in a rectangular structure with rounded corners claim 4 , the four first walls are located at the four rounded corners of the voice coil respectively.6. The sound generator as described in claim 5 , wherein the dome body is in a rectangular structure claim 5 , the two first walls and the two second walls ...

KITS, MICROFLUIDICS DEVICES, AND METHODS FOR PERFORMING BIOTIN ASSAYS

Kits containing a chemiluminescent detection system and microfluidics devices and methods for determining the concentration of biotin in a sample are disclosed. The kits, microfluidics devices, and methods utilize a sensitizer capable of generating singlet oxygen in its excited state and having avidin or an analog thereof directly or indirectly bound thereto, as well as a singlet oxygen-activatable chemiluminescent compound having biotin or an analog thereof directly or indirectly bound thereto. 1. A kit containing a chemiluminescent detection system for determining the concentration of biotin in a sample , the kit comprising:(a) a composition comprising a singlet oxygen-activatable chemiluminescent compound having biotin or an analog thereof directly or indirectly bound thereto; and(b) a composition comprising a sensitizer capable of generating singlet oxygen in its excited state and having traptavidin directly or indirectly bound thereto.2. The kit of claim 1 , wherein the composition of (a) has a biotin analog directly or indirectly bound to the singlet oxygen-activatable chemiluminescent compound claim 1 , and wherein the biotin analog is selected from the group consisting of 4′-hydroxyazobenzene-2-carboxylic acid (HABA) claim 1 , iminobiotin claim 1 , biotin carbonate claim 1 , biotin carbamate claim 1 , biotin methyl ester claim 1 , desthiobiotin claim 1 , diaminobiotin claim 1 , chloroacetylated biotin claim 1 , biotin sulfone claim 1 , thiobiotin claim 1 , methoxycarbonylbiotin methyl ester claim 1 , bis-biotin claim 1 , tetra-biotin claim 1 , and any ester claim 1 , salt claim 1 , or derivative of any of the above analogs.3. The kit of claim 2 , wherein the biotin analog is HABA or iminobiotin.4. The kit of claim 1 , wherein the singlet oxygen-activatable chemiluminescent compound is a substance that undergoes a chemical reaction with singlet oxygen to form a metastabile intermediate species that can decompose with the simultaneous or subsequent emission of ...

ELECTRONIC DEVICE

An electronic device includes a first portion and a second portion, an electric power generating device and a load device. The electronic device is disposed in an opening of a connected space, and the electronic device and a wall have the opening divide the connected space into the first space and the second space. The first portion is located in a first space having a first ambient temperature, and the second portion is located in a second space having a second ambient temperature. The electric power generating device is configured to generate a thermo-electromotive force based on a temperature difference between the first ambient temperature and the second ambient temperature to generate electrical energy. The load device is configured to obtain the electrical energy and operate on the electrical energy. 1. An electronic device , comprising:a first portion and a second portion, the electronic device being disposed in an opening of a connected space, the electronic device and a wall having the opening dividing the connected space into the first space and the second space, the first portion being located in a first space having a first ambient temperature, and the second portion being located in a second space having a second ambient temperature;an electric power generating device configured to generate a thermo-electromotive force based on a temperature difference between the first ambient temperature and the second ambient temperature to generate electrical energy; anda load device configured to obtain the electrical energy and operate on the electrical energy.2. The electronic device according to claim 1 , wherein:in response to the first ambient temperature being higher than the second ambient temperature, the electric power generating device generates a first thermo-electromotive force; andin response to the first ambient temperature being lower than the second ambient temperature, the electric power generating device generates a second thermo-electromotive ...

Configuration device and method

A configuration apparatus includes a processor and a memory. The processor is configured to obtain first data of a first device, the first data indicating that the first device is ready for network configuration. The memory is configured to store network configuration data of a second device. The processor is further configured to: obtain the network configuration data of the second device, and send the network configuration data to the first device, the network configuration data being used to configure the first device to be in a same network connection state as the second device. A power path exists between the first device and the second device, and at least one of the first data or the network configuration data is transmitted through the power path.

SOUNDING DEVICE

A sounding device includes a shell, a vibrating system and a driving unit. The vibrating system includes a vibrating diaphragm, a magnetic vibrating plate, and a transmission piece. The magnetic vibrating plate includes a fixing portion fixed on the shell and a body portion bent and extended from the fixing portion and arranged oppositely to the vibrating diaphragm. The driving unit includes a coil and a magnet portion fixed relatively to the shell. The coil winds on the body portion, and an orthographic projection of the magnet portion falls onto the body portion and is close to the transmission piece, the magnet portion and the body portion are arranged separately. At least two magnetic vibrating plates respectively drive different positions of the vibrating diaphragm, and the magnetic vibrating plates correspond to the driving units one by one. 1. A sounding device , comprising a shell with an accommodating space , as well as a vibrating system and a driving unit accommodated in the accommodating space; the magnetic vibrating plate and the vibrating diaphragm are arranged separately;', {'sub': ';', 'the body portion is suspended in the accommodating space, the transmission piece is sandwiched between one end of the body portion far away from the fixing portion and the vibrating diaphragmand the magnetic vibrating plate pushes the vibrating diaphragm to vibrate and generate sound through the transmission piece;'}, 'the magnetic vibrating plate comprises a fixing portion fixed to the shell and a body portion bent and extended from the fixing portion and arranged oppositely to the vibrating diaphragm;'}], 'wherein the vibrating system comprises a vibrating diaphragm fixed to the shell, a magnetic vibrating plate driving the vibrating diaphragm to vibrate, and a transmission piece connecting the vibrating diaphragm with the magnetic vibrating plate;'} 'an orthographic projection of the magnet portion on the body portion falls onto the body portion, the magnet portion ...

SOUND GENERATING DEVICE

The present invention provides a sound generating device, including a housing and a vibration system accommodated in the housing, the vibration system including a diaphragm and a driving unit for driving the diaphragm to vibrate and generate sound. The driving unit includes a piezoelectric driving unit and a moving iron driving unit coupled in parallel with the piezoelectric driving unit, the piezoelectric driving unit including a piezoelectric sheet, the moving iron driving unit including a coil and a magnetic steel. The piezoelectric driving unit and the moving iron driving unit jointly drive the diaphragm to vibrate and sound. 1. A sound generating device , comprising a housing , a vibration system accommodated in the housing and a circuit board , the vibration system comprising a diaphragm and a driving unit for driving the diaphragm to vibrate and generate sound , wherein 'wherein the piezoelectric driving unit comprises a piezoelectric sheet, and the moving iron driving unit comprises a coil and a magnetic steel;', 'the driving unit comprises a piezoelectric driving unit and a moving iron driving unit coupled in parallel with the piezoelectric driving unit;'}andthe piezoelectric driving unit and the moving iron driving unit jointly drive the diaphragm to vibrate and generate sound.2. The sound generating device in accordance with claim 1 , wherein the piezoelectric driving unit comprises a first base fixed to the housing and fixed to both ends of the piezoelectric sheet claim 1 , a first support extending from the piezoelectric sheet toward the diaphragm and connected to the diaphragm claim 1 , and a bump fixing the piezoelectric sheet to the first base.3. The sound generating device in accordance with claim 2 , wherein the first support is integrally formed with the piezoelectric sheet.4. The sound generating device in accordance with claim 2 , wherein the moving iron driving unit comprises a second base fixed to the housing and accommodating the coil claim 2 ...

Speaker

The present invention relates to a speaker having a frame, a magnetic circuit system and a vibrating system. The magnetic circuit system has a main magnet and an auxiliary magnet. The vibrating system has a vibrating diaphragm, a voice coil and a suspension with a first avoiding space. The auxiliary magnet is surrounding the main magnet and passed through the first avoiding space. The first avoiding space is positioned in the suspension so that the auxiliary magnet can be arranged around the main magnet, thereby enhancing the strength of the magnetic field of the magnetic circuit system, and ensuring uniform force on the vibrating diaphragm for improving BLX symmetry of the vibrating diaphragm. 1. A speaker , comprising a frame , a magnetic circuit system and a vibrating system , where in , both the magnetic circuit system and the vibrating system are accommodated within the frame ,the magnetic circuit system including a yoke, a main magnet, an auxiliary magnet, a main pole core and an auxiliary pole core, where in, the main magnet and the auxiliary magnet are both arranged on the yoke, the auxiliary magnet surrounds the main magnet, the main pole core and the auxiliary pole core are attached to the main magnet and the auxiliary magnet respectively, the main magnet is spaced apart from the auxiliary magnet and a magnetic gap is formed between the main magnet and the auxiliary magnet;the vibrating system comprising a vibrating diaphragm, a voice coil for driving the vibrating diaphragm for vibrating along a vibrating direction, and a suspension, wherein, one end of the voice coil is connected to the vibrating diaphragm, the other end of the voice coil is suspended within the magnetic gap; and the suspension is located between the yoke and the auxiliary pole core;the auxiliary magnet including a first auxiliary magnet provided on the two opposite sides of the main magnet, where in, an orthographic projection of the suspension on the yoke along the vibrating direction ...

Speaker

The present invention discloses a speaker having a frame, a vibrating system and a magnetic circuit system. The vibrating system has a vibrating diaphragm, a voice coil for driving the vibrating diaphragm, and an elastic supporting assembly fixed on the frame and connected to the voice coil. The magnetic circuit system has a main magnet, a secondary magnet spaced on two opposite sides of the main magnet, a magnetic plate stacked on the secondary magnet and spaced away from the elastic supporting assembly, and an auxiliary magnet fixed on the magnetic plate and spaced away from the main magnet. The elastic supporting assembly is positioned on the other two opposite sides of the main magnet. The auxiliary magnetic located close to the vibrating diaphragm and facing to the elastic supporting assembly. The speaker of the present invention has advantages of good reliability and excellent acoustic performance. 1. A speaker , comprising a frame , a vibrating system and a magnet circuit system with a magnetic gap both accommodated in the frame respectively ,wherein, the vibrating system comprises a vibrating diaphragm fixed on the frame, a voice coil inserted into the magnetic gap for driving the vibrating diaphragm, and an elastic supporting assembly fixed on the frame and connected to the voice coil at an end away from the vibrating diaphragm;the magnetic circuit system comprises a yoke fixed on the frame, a main magnet fixed on the yoke, a secondary magnet located on two opposite sides of the main magnet and spaced away from the main magnet for forming the magnetic gap, and a magnetic plate stacked on the secondary magnet and spaced away from the elastic supporting assembly;an orthographic projection of the elastic supporting assembly on the yoke along a vibrating direction of the diaphragm, and an orthographic projection of the secondary magnet on the yoke along the vibrating direction of the diaphragm at least do not overlap partially;the magnetic plate is an annular ...

SPEAKER

A speaker includes a holder having a receiving space, a magnetic circuit unit and a vibration unit. The vibration unit includes a diaphragm, a voice coil driving the diaphragm to vibrate, and a centering support member. The centering support member includes a connecting portion between the upper diaphragm and the voice coil, extension portions extending from two ends of the connecting portion and towards the magnetic circuit unit, and body portions each formed by extending from an tail end of each extension portion while being bent in a direction facing away from the extension portion. The connecting portion is interposed between the diaphragm and the voice coil. The extension portion is located between the magnetic circuit unit and the holder. An end the body portion is connected to the holder, and the other end is connected to the voice coil to support the voice coil. 1. A speaker , comprising:a holder having a receiving space;a magnetic circuit unit received in the receiving space; anda vibration unit received in the receiving space, a diaphragm comprising an upper diaphragm fixed above the holder, and a lower diaphragm opposite to and spaced apart from the upper diaphragm and received in the receiving space;', 'a voice coil configured to drive the diaphragm to vibrate; and', 'a centering support member connecting the upper diaphragm with the lower diaphragm,, 'wherein the vibration unit comprises a connecting portion interposed between the upper diaphragm and the voice coil;', 'extension portions respectively extending from two ends of the connecting portion that are opposite to each other along a long axis direction of the connecting portion, and respectively extending towards the magnetic circuit unit; and', 'body portions each extending from a tail end of one of the extension portions while being bent in a direction facing away from the one of the extension portions,, 'wherein the centering support member compriseswherein the extension portions are located ...

Speaker

The present invention discloses a speaker having a frame, a vibrating system and a magnet circuit system. The vibrating system has a vibrating diaphragm, a voice coil, and an elastic supporting. The magnetic circuit system has a main magnet, as secondary magnet located and spaced on two opposite sides of the main magnet, and a magnetic plate stacked on the secondary magnet and spaced away from the elastic supporting assembly. The magnetic plate includes a main body stacked on the secondary magnet and an extending wall extending from two opposite sides of the main body towards the main magnet and spaced away from the voice coil. The extending wall is facing and spaced away from the elastic supporting assembly. The speaker of the present invention has an excellent acoustic performance. 1. A speaker , comprising a frame , a vibrating system and a magnet circuit system with a magnetic gap both accommodated in the frame respectively ,wherein, the vibrating system comprises a vibrating diaphragm fixed on the frame, a voice coil driving the vibrating diaphragm and inserted into the magnetic gap for driving the vibrating diaphragm, and an elastic supporting assembly fixed on the frame and connected to the voice coil at an end away from the vibrating diaphragm;the magnetic circuit system comprises a yoke fixed on the frame, a main magnet fixed on the yoke, a secondary magnet located on two opposite sides of the main magnet and spaced away from the main magnet for forming the magnetic gap, and a magnetic plate stacked on the secondary magnet and spaced away from the elastic supporting assembly;an orthographic projection of the elastic supporting assembly on the yoke along a vibrating direction of the vibrating diaphragm, and an orthographic projection of the secondary magnet on the yoke along the vibration direction of the vibrating diaphragm at least do not overlap partially; andthe magnetic plate includes a main body in an annular shape stacked on the secondary magnet and ...

Speaker

The present invention discloses a speaker having a frame, a vibrating system and a magnetic circuit system. The vibrating system has a vibrating diaphragm, a voice coil and an elastic supporting assembly. The magnetic circuit system has a main magnet, a secondary magnet and a magnetic plate having a main body and a supporting portion opposite to the elastic supporting assembly. The elastic supporting assembly has an avoiding hole penetrating there through and facing to the supporting portion. The yoke has a yoke body fixed on the frame and an extending portion extending from two opposite sides of the yoke body towards the supporting portion. The extending portion passes through the avoiding hole thereof and attach on the supporting portion. The speaker of the present invention has advantages of good reliability and excellent acoustic performance.

SPEAKER

A speaker includes a holder, a magnetic circuit unit, and a vibration unit including a diaphragm, a voice coil, and a centering support plate. The centering support plate is fixed to a side of the voice coil facing away from the diaphragm. One end of the centering support plate fixed to the voice coil is provided with a pad electrically connected to the voice coil. The diaphragm includes a central portion, a suspension portion surrounding the central portion, and a dome fixed to the central portion. The dome includes a body attached to the central portion, and a connection portion extending from an edge of the body towards the pad and fixedly connected to the pad. With the connection portion, the pad of the centering support plate can be fixed, preventing the tone quality of the speaker from being damaged by the pad, and t reducing noise. 1. A speaker , comprising:a holder;a magnetic circuit unit received in the holder; anda vibration unit received in the holder, a diaphragm;', 'a voice coil configured to drive the diaphragm to vibrate; and', 'a centering support plate, one end of the centering support plate being fixed to the holder and the other end of the centering support plate being fixed to the voice coil, the centering support plate being fixed to a side of the voice coil facing away from the diaphragm, the end of the centering support plate fixed to the voice coil is provided with a pad electrically connected to the voice coil,, 'wherein the vibration unit comprises a central portion;', 'a suspension portion surrounding the central portion; and', 'a dome fixed to a side of the central portion close to the voice coil, the dome comprising a body attached to the central portion, and a connection portion extending from an edge of the body towards the pad and fixedly connected to the pad., 'wherein the diaphragm comprises2. The speaker as described in claim 1 , wherein the magnetic circuit unit comprises a main magnet arranged correspondingly to the central ...

Sound Generator

An embodiment of the present invention provides a sound generator having a frame; a magnetic circuit system fixed to the frame, and a vibration system. The magnetic circuit system includes a main magnet and an auxiliary magnet surrounding the main magnetic. The vibration system includes a vibrating diaphragm having a first vibrating diaphragm, a second vibrating diaphragm, and a dome for connecting the first vibrating diaphragm to the second vibrating diaphragm. A gap is formed between the auxiliary magnet and the frame. The dome has a body part, two first extension parts, and two second extension parts. The first extension part is located within the gap. Accordingly, the sound generator can solve the swing problem, and improve the low frequency performance. 1. A sound generator comprising:a frame;a magnetic circuit system fixed to the frame, comprising a main magnet and an auxiliary magnet surrounding the main magnetic;a gap formed between the auxiliary magnet and the frame; a vibrating diaphragm having a first vibrating diaphragm, a second vibrating diaphragm, and a dome for connecting the first vibrating diaphragm to the second vibrating diaphragm; and', 'a voice coil for driving the vibrating diaphragm to vibrate; wherein, 'a vibration system including'}the dome comprises a body part fixed to the first vibrating diaphragm, two first extension parts formed by extending toward the second vibrating diaphragm from two opposite ends of the body part respectively, and two second extension parts bending and extending from two ends of the first extension parts and fixed with the second vibrating diaphragm; and the first extension part is located within the gap.2. The sound generator as described in claim 1 , wherein the body part comprises a first surface fixed to the vibrating diaphragm claim 1 , the dome further comprises an abutting part concave and extending from the first surface to the voice coil.3. The sound generator as described in claim 2 , wherein the voice ...

SOUND DEVICE

The present invention provides a sound device, which includes a bottom plate, a support fixed to the bottom plate, a frame arranged on the support, and a diaphragm fixed to the frame. The sound device further includes a first piezoelectric ceramic sheet and a second piezoelectric ceramic sheet that are disposed separately on the support, and the first piezoelectric ceramic sheet and the second piezoelectric ceramic sheet are respectively provided with a transmission member abutting against the diaphragm. The sound device in the present disclosure can increase a driving force, increase a vibration amplitude, enhance a product sensitivity, broaden a response range, increase a driving fulcrum, improve a vibration balance, and avoid a product distortion. 1. A sound device , comprising a bottom plate , a support fixed to the bottom plate , a frame arranged on the support , and a diaphragm fixed to the frame , wherein the sound device further comprises a first piezoelectric ceramic sheet and a second piezoelectric ceramic sheet that are disposed separately on the support , and the first piezoelectric ceramic sheet and the second piezoelectric ceramic sheet are respectively provided with a transmission member abutting against the diaphragm.2. The sound device in accordance with claim 1 , wherein the first piezoelectric ceramic sheet and the second piezoelectric ceramic sheet are arranged in parallel.3. The sound device in accordance with claim 1 , wherein the first piezoelectric ceramic sheet and the second piezoelectric ceramic sheet are connected by a connecting member arranged on an outer wall surface of the frame or the outer wall surface of the support.4. The sound device in accordance with claim 1 , wherein the first piezoelectric ceramic sheet and the second piezoelectric ceramic sheet are connected in parallel.5. The sound device in accordance with claim 1 , wherein the first piezoelectric ceramic sheet and the second piezoelectric ceramic sheet are further ...

VEHICLE PATH-PLANNER MONITOR AND CONTROLLER

Systems of an autonomous vehicle and the operations thereof are provided. Autonomous vehicles may rely on data inputs, processes, and output commands. Errors due to translation errors, failed or faulty equipment, connections, and other components may cause a dynamic vehicle path to approach a dynamic safe zone or vice versa. If so, a warning message may be sent and processed by the motion control system, when the vehicle is responding to commands correctly, or actuator control, when the vehicle is not responding to commands correctly. Should a safe zone be redrawn to exclude the vehicle's path, a failure message is sent to the appropriate system for mitigation. 120-. (canceled)21. An autonomous driving system , comprising:a processor comprising circuitry and a memory;a sensor in communication with the processor;an actuator control that receives a motion control command and converts the motion control command into an actuator command;an actuator that, in response to receiving an actuator command, executes an operation controlling an aspect of locomotion for a vehicle and further provides an actuator feedback signal;a motion control system that determines a path boundary and provides motion control commands to the actuator to cause the vehicle to traverse the path boundary, wherein the path boundary defines an expected location of the vehicle for a particular timeframe; and accesses a safe zone boundary for the vehicle, wherein the safe zone boundary defines a dynamic envelope that the vehicle may operate in to avoid an identified object while traversing the path boundary;', 'recalculates the safe zone boundary upon observing a movement of the identified object;', 'determines whether the path boundary has breached the safe zone boundary as recalculated;', 'in response to determining that the safe zone boundary has been breached, determines whether the actuator feedback is divergent from the motion control commands; and', 'in response to determining that the actuator ...

CHROMATOGRAPHIC MATERIAL AND METHODS FOR THE SYNTHESIS THEREOF

A particulate material for chromatographic use comprising silica particles is provided having a skeleton structure containing silsesquioxane cage moieties. The material is useful as a chromatographic material, for example in HPLC. The silica particles may be hybrid organo-silica particles wherein the silsesquioxane moieties comprise a cage structure having silicon atoms positioned at corners of the cage wherein one or more silicon atoms positioned at the corners of the cage carry an organic group. A preferred method of preparing the particulate material comprises hydrolysing a silsesquioxane as a co-component of a hydrolysis mixture, especially in a Stöber or modified Stöber process. 1. A liquid chromatography stationary phase comprising:silica particles formed via co-condensation of a Si moiety of an alkoxysilane with a silsesquioxane moiety in a presence of a surfactant, a water, an organic solvent, and a base,in which the silsesquioxane moiety has a cage structure,in which the silica particles include Si-silsesquioxane-Si linkages,in which the silica particles comprise an internal structure and a surface,in which the silsesquioxane moieties are contained in the internal structure of the silica particles via the Si-silsesquioxane-Si linkages, andin which the silica particles are configured to be packed into a chromatography column.2. The liquid chromatography stationary phase of claim 1 , wherein the silica particles are hybrid organo-silica particles claim 1 , wherein the cage structure of the silsesquioxane moieties comprise silicon atoms positioned at corners of the cage structure claim 1 , wherein one or more of the silicon atoms positioned at the corners of the cage structure include an organic group.3. The liquid chromatography stationary phase of claim 2 , wherein the organic group is a hydrocarbon group.4. The liquid chromatography stationary phase of claim 2 , wherein the hybrid organo silica particles have a formula selected from the group consisting of: ...

FAIL-OPERATIONAL ARCHITECTURE WITH FUNCTIONAL SAFETY MONITORS FOR AUTOMATED DRIVING SYSTEM

Systems and methods are disclosed for dynamically adjusting effective sensor coverage coordinates of a sensor used to assist in navigating an autonomous driving vehicle (ADV) in response to environmental conditions that may affect the ideal operation of the sensor. An ADV includes a navigation system and a safety monitor system that monitors some, or all, of the navigation system, including monitoring: dynamic adjustment of effective sensor coverage coordinates of a sensor and localization of the ADV within a high-definition map. The ADV safety monitor system further determines safety-critical objects surrounding the ADV, determines safe areas to navigate the ADV, and ensures that the ADV navigates only to safe areas. An automated system performance monitor determines whether to pass-through ADV navigation control commands, limit one or more control commands, or perform a fail-operational behavior, based on the ADV safety monitor systems. 1. A computer-implemented method of safely navigating an autonomous driving vehicle (ADV) comprising:determining a route to navigate the ADV based at least in part upon localizing the ADV in a high-definition (HD) map in view of one or more objects surrounding the ADV;determining an effective sensor coverage area of each of a plurality of sensors of the ADV;defining one or more safe drivable areas, based at least in part on the route and the effective sensor coverage area of each of the plurality of sensors of the ADV;monitoring the effective sensor coverage area of each of the sensors, while navigating of the ADV along the route in response to a plurality of navigation control inputs from an ADV navigation system; andmodifying one or more of the plurality of navigation control inputs in response to determining that a safety action is required based on monitoring the effective sensor coverage area.2. The method of claim 1 , wherein modifying one or more of the plurality of navigation control inputs comprises:determining that a ...

METHOD TO DYNAMICALLY DETERMINE VEHICLE EFFECTIVE SENSOR COVERAGE FOR AUTONOMOUS DRIVING APPLICATION

Systems and methods are disclosed for dynamically adjusting effective sensor coverage coordinates of a sensor used to assist in navigating an autonomous driving vehicle (ADV) in response to environmental conditions that may affect the ideal operation of the sensor. An ADV includes a navigation system and a safety monitor system that monitors some, or all, of the navigation system, including monitoring: dynamic adjustment of effective sensor coverage coordinates of a sensor and localization of the ADV within a high-definition map. The ADV safety monitor system further determines safety-critical objects surrounding the ADV, determines safe areas to navigate the ADV, and ensures that the ADV navigates only to safe areas. An automated system performance monitor determines whether to pass-through ADV navigation control commands, limit one or more control commands, or perform a fail-operational behavior, based on the ADV safety monitor systems. 1. A computer-implemented method of dynamically adjusting effective sensor coverage coordinates of a first sensor in an autonomous driving vehicle (ADV) , the method comprising:determining a list of one or more objects surrounding the ADV based on a high-definition (HD) map;identifying a first static object based on first sensor data of the first sensor;in response to determining that the identified first static object matches one of the one or more objects in the HD map and the first static object is located outside of the effective sensor coverage coordinates of the first sensor, increasing the effective sensor coverage coordinates of the first sensor to include a location of the first static object; andnavigating the ADV to avoid the first static object in view of the increased effective sensor coverage coordinates.2. The method of claim 1 , wherein determining a list of one or more objects surrounding the ADV comprises at least one of:locating the one or more objects in the HD map surrounding a path of the ADV;locating the one ...

METHOD TO DEFINE SAFE DRIVABLE AREA FOR AUTOMATED DRIVING SYSTEM

Systems and methods are disclosed for dynamically adjusting effective sensor coverage coordinates of a sensor used to assist in navigating an autonomous driving vehicle (ADV) in response to environmental conditions that may affect the ideal operation of the sensor. An ADV includes a navigation system and a safety monitor system that monitors some, or all, of the navigation system, including monitoring: dynamic adjustment of effective sensor coverage coordinates of a sensor and localization of the ADV within a high-definition map. The ADV safety monitor system further determines safety-critical objects surrounding the ADV, determines safe areas to navigate the ADV, and ensures that the ADV navigates only to safe areas. An automated system performance monitor determines whether to pass-through ADV navigation control commands, limit one or more control commands, or perform a fail-operational behavior, based on the ADV safety monitor systems. 1. A computer-implemented method of operating an autonomous driving vehicle (ADV) comprising:generating a list of one or more safety-critical objects based on sensor data obtained from one or more sensors of the ADV, wherein safety-critical objects comprise one or more static objects and one or more dynamic objects that are located in a first area, the first area overlapping at least a portion of a drivable path of the ADV;identifying a list of one or more objects perceived based on the sensor data obtained from the sensors of the ADV in view of environmental conditions surrounding the ADV; and searching the list of objects to find the safety-critical object, and', 'in response to determining that the safety-critical object is not found within the list of objects, performing a fail-operational action to navigate the ADV., 'for each of the safety-critical objects,'}2. The method of claim 1 , wherein environmental conditions include one or more of:daylight, darkness, weather, or debris.3. The method of claim 1 , wherein safety- ...

Method for real-time monitoring of safety redundancy autonomous driving system (ads) operating within predefined risk tolerable boundary

In one embodiment, method for real-time monitoring of a safety redundancy autonomous driving system operating within a predefined risk tolerable boundary includes calculating a zone failure risk score for each of predetermined zones based on a sensor failure risk score associated with each of sensors mounted on the ADV. The predetermined zones being defined based on a sensor layout of the sensors. A sensor capability coverage of the ADV is determined based on the zone failure risk score associated with each of the predetermined zones. A drivable area of the ADV is determined based on the sensor capability coverage in view of map data associated with a current location of the ADV. A trajectory is planned based on the drivable area to autonomously drive the ADV to navigate a driving environment surrounding the ADV.

Adversarial pretraining of machine learning models

This document relates to training of machine learning models. One example method involves providing a machine learning model having one or more mapping layers. The one or more mapping layers can include at least a first mapping layer configured to map components of pretraining examples into first representations in a space. The example method also includes performing a pretraining stage on the one or more mapping layers using the pretraining examples. The pretraining stage can include adding noise to the first representations of the components of the pretraining examples to obtain noise-adjusted first representations. The pretraining stage can also include performing a self-supervised learning process to pretrain the one or more mapping layers using at least the first representations of the training data items and the noise-adjusted first representations of the training data items.

SYSTEMS AND METHODS TO DETERMINE RISK DISTRIBUTION BASED ON SENSOR COVERAGES OF A SENSOR SYSTEM FOR AN AUTONOMOUS DRIVING VEHICLE

Systems and methods of determining a risk distribution associated with a multiplicity of coverage zones covered by a multiplicity of sensors of an autonomous driving vehicle (ADV) are disclosed. The method includes for each coverage zone covered by at least one sensor of the ADV, obtaining MTBF data of the sensor(s) covering the coverage zone. The method further includes determining a mean time between failure (MTBF) of the coverage zone based on the MTBF data of the sensor(s). The method further includes computing a performance risk associated with the coverage zone based on the determined MTBF of the coverage zone. The method further includes determining a risk distribution based on the computed performance risks associated with the multiplicity of coverage zones. 1. A computer-implemented method of determining a risk distribution associated with a plurality of coverage zones covered by a plurality of sensors of an autonomous driving vehicle (ADV) , the method comprising: obtaining MTBF data of the at least one sensor covering the coverage zone,', 'determining a mean time between failure (MTBF) of the coverage zone based on the MTBF data of the at least one sensor, and', 'computing a performance risk associated with the coverage zone based on the determined MTBF of the coverage zone; and, 'for each coverage zone covered by at least one sensor of the ADV,'}determining a risk distribution based on the computed performance risks associated with the plurality of coverage zones.2. The method of claim 1 , further comprising:determining whether the ADV is operating in autonomous driving (AD) mode;in response to determining that the ADV is operating in the AD mode, starting an AD mode timer;determining whether the AD mode timer reaches the MTBF of the coverage zone;determining whether the MTBF of the coverage zone has timed out; andin response to determining that the MTBF of the coverage zone has timed out, monitoring performance limitation of the at least one sensor ...

EFFICIENT TRANSFORMER LANGUAGE MODELS WITH DISENTANGLED ATTENTION AND MULTI-STEP DECODING

Systems and methods are provided for facilitating the building and use of natural language understanding models. The systems and methods identify a plurality of tokens and use them to generate one or more pre-trained natural language models using a transformer. The transformer disentangles the content embedding and positional embedding in the computation of its attention matrix. Systems and methods are also provided to facilitate self-training of the pre-trained natural language model by utilizing multi-step decoding to better reconstruct masked tokens and improve pre-training convergence. 1. A computing system configured to account for position bias while encoding data with a transformer , the computing system comprising:one or more processors; and identify a plurality of tokens to be encoded from a sequence;', 'obtain a transformer that includes an encoder, the encoder including a self-attention sub-layer and a feed forward sub-layer;', 'embed the plurality of tokens to generate input data;', 'apply the input data to the encoder; and', a first attention score component comprising a product of a content embedding of a first token in a token pair, a first learn-able content parameter, a second learn-able content parameter, and a content embedding of a second token in a token pair;', 'a second attention score component comprising a product of the content embedding of the first token in the token pair, the first learn-able content parameter, a first learnable position parameter, and a relative position embedding of the first and second tokens in a token pair; and', 'a third attention score component comprising a product of the relative position embedding of the first and second tokens in the token pair, a second learn-able position parameter, the second learn-able content parameter, and the second content embedding of a second token in a token pair., 'generate and apply an attention score at the self-attention sub-layer, by at least disentangling position bias ...

Image Processing Method and Device

An image processing method and device are disclosed. The method is applicable to an image processing device having an operating system, and the method includes: receiving, by an image processing module of the operating system, an instruction of a first application program to call the image processing module of the operating system, where the instruction carries a to-be-displayed image and a resolution of the to-be-displayed image; and when the resolution of the to-be-displayed image is less than a first threshold, performing, by the image processing module, super-resolution processing on the to-be-displayed image, and displaying an image obtained after the super-resolution processing, to resolve a problem of a low image definition in a conventional display method. 1. An image processing method , implemented by an image processing device comprising an operating system , wherein the image processing method comprises:receiving an instruction of a first application program to call an image processing function of the operating system, wherein the instruction carries a to-be-displayed image;perfoming image optimization processing on the to-be-displayed image; anddisplaying an image obtained after the image optimization processing.2. The image processing method of claim 1 , further comprising performing super-resolution processing on the to-be-displayed image when a resolution of the to-be-displayed image is less than a first threshold.3. The image processing method of claim 2 , wherein the instruction further comprises an identifier of the first application program claim 2 , and wherein the image processing method further comprises determining that the first application program has a super-resolution processing permission based on the identifier of the first application program.4. The image processing method of claim 3 , further comprising:determining whether the identifier of the first application program exists in a preset whitelist; anddetermining that the first ...

VEHICLE-MOUNTED SYSTEM AND VEHICLE

A vehicle-mounted system and a vehicle are disclosed. The vehicle-mounted system includes a vehicle lamp system, the vehicle lamp system includes a direction changing unit or/and a light intensity adjusting unit and a vehicle lamp; the vehicle lamp is arranged on a front side of a vehicle body and configured to emit light; the direction changing unit is arranged on a light emergent side of the vehicle lamp, and configured to change a transmission direction of light that is incident on the direction changing unit and emitted by the vehicle lamp; and the light intensity adjusting unit is configured to adjust intensity of the light emitted by the vehicle lamp. 1. A vehicle-mounted system , comprising a vehicle lamp sub-system ,wherein the vehicle lamp sub-system includes at least one of a direction changer and a light intensity adjuster and a vehicle lamp;the vehicle lamp is arranged on a front side of a vehicle body and configured to emit light;the direction changer is arranged on a light emergent side of the vehicle lamp, and configured to change a transmission direction of light that is incident on the direction changer and emitted by the vehicle lamp; andthe light intensity adjuster is configured to adjust intensity of the light emitted by the vehicle lamp.2. The vehicle-mounted system according to claim 1 , wherein the vehicle lamp includes a left region claim 1 , a middle region claim 1 , and a right region;the vehicle lamp sub-system further includes a first controller, the first controller being configured to control at least one of a transmission direction and intensity of the light emitted by the vehicle lamp by controlling at least one of the direction changer and the light intensity adjuster.3. The vehicle-mounted system according to claim 2 , wherein the direction changer is at least configured to make the light emitted from the left region or the right region of the vehicle lamp respectively irradiate to a left front or a right front of the vehicle body.4 ...

APPLICATION OF ASARUM TOTAL POLYSACCHARIDES IN PREPARATION OF MEDICINE FOR TREATING COUGH

The present invention discloses an total polysaccharide extract with antitussive activity, an extraction method thereof and an application in the preparation of a medicine for preventing and treating coughs. The present invention proves that the total polysaccharide extract has a significant effect of suppressing cough for the first time through a large number of pharmacodynamic tests, has the therapeutic effect approximate to codeine, has the effect of prolonging the cough latent period better than codeine, and also finds that the total polysaccharide extract has the effects of reducing the cough sensitivity and suppressing the airway inflammation for the first time, has excellent preventive and therapeutic effects on various types of coughs, and can be used for preparing the medicines for preventing and treating cough-related diseases. 1AsarumAsarum. An application of total polysaccharides in preparation of medicine for treating cough , wherein the total polysaccharides is prepared by a process comprising:{'i': 'Asarum', 'a. subjecting roots and/or rhizomes of to a heat reflux using water;'}{'i': 'Asarum', 'b. concentrating and drying under vacuum to produce an total extract;'}{'i': Asarum', 'Asarum', 'Asarum, 'c. dissolving the total extract in water to produce an total extract solution and adding 60-99% ethanol by volume into the total extract solution to completely precipitate to produce a supernate and a precipitate;'}d. discarding the supernate and filtering the precipitate under vacuum;{'i': 'Asarum', 'e. washing the filtered precipitate with 60-100% ethanol by volume and drying under vacuum to obtain the total polysaccharides.'}2. The application of claim 1 , wherein the cough is chronic cough.3Asarum. The application of claim 1 , wherein the content of polysaccharides in the total polysaccharides is 60-80 wt %.4Asarum. The application of claim 1 , wherein a pharmaceutical composition is made from the total polysaccharides and a pharmaceutically acceptable ...

SYSTEMS FOR FORMING PHOTOVOLTAIC CELLS ON FLEXIBLE SUBSTRATES

A deposition system for depositing a thin film photovoltaic cell on a flexible substrate comprises an enclosure that is fluidically isolated from an environment external to the enclosure, and a plurality of deposition chambers in the enclosure. At least one deposition chamber of the plurality of deposition chambers comprises a magnetron sputtering apparatus that directs a material flux of one or more target materials towards a portion of the flexible substrate that is disposed in the at least one deposition chamber of the plurality of deposition chambers. A substrate payout roller in the enclosure provides a flexible substrate that is directed through each of the plurality of deposition chambers to a substrate take-up roller in the enclosure. At least one guide roller in the enclosure is configured to direct the flexible substrate to or from a given deposition chamber among the plurality of deposition chambers. 1. A deposition system for depositing a thin film photovoltaic cell on a flexible substrate , comprising:a) an enclosure comprising a fluid space that is fluidically isolated from an environment external to said enclosure;b) a plurality of deposition chambers in said fluid space, wherein at least one deposition chamber of said plurality of deposition chambers comprises a magnetron sputtering apparatus that directs a material flux of one or more target materials towards a portion of said flexible substrate that is disposed in said at least one deposition chamber of said plurality of deposition chambers;b1) wherein each of said deposition chambers that comprises a magnetron sputtering apparatus includes openings through which said flexible substrate passes and adjustable conductance limiters arranged at said openings to form a gap between said substrate and said conductance limiter;c) a substrate payout roller and a substrate take-up roller in said enclosure, wherein said substrate payout roller provides a flexible substrate that is directed through each of ...

REPLACEABLE EMITTER ASSEMBLY FOR INTERFACING A SEPARATION COLUMN TO A MASS SPECTROMETER

An electrospray emitter assembly for interfacing a separation column to a mass spectrometer is disclosed. An emitter capillary includes an inlet end and an outlet end. A fitting is coupled to the inlet end of the emitter, configured to be removably connected to the separation column. A stop with a defined through hole is integrated proximate the inlet end of the emitter to produce a path for liquid to flow from the separation column to the emitter via the through hole where a voltage is applied to the liquid entering the emitter. 1. (canceled)2. An electrospray emitter assembly for interfacing a separation column to a mass spectrometer , comprising:a. an emitter capillary having an inlet end and an outlet end; andb. a fitting coupled to the inlet end of the emitter, configured to be removably connected to the separation column;wherein a stop with a defined through hole is integrated proximate the inlet end of the emitter to produce a path for liquid to flow from the separation column to the emitter via the through hole where a voltage is applied to the liquid entering the emitter.3. The emitter assembly of wherein the fitting is a female threaded end fitting.4. The emitter assembly of wherein the emitter capillary comprises a fused silica capillary claim 2 , a metal capillary claim 2 , a ceramic capillary claim 2 , or a glass capillary.5. The emitter assembly of wherein the separation column is removably connected via a transfer line with the emitter capillary through the fitting.6. The emitter assembly of wherein the integrated stop has a thickness of up to 1.0 mm.7. The emitter assembly of wherein the integrated stop has a thickness of between 100 μm to 300 μm.8. The emitter assembly of wherein the through hole in the stop has a diameter of between 3μm and 100 μm.9. The emitter assembly of further comprising a protective sleeve for covering and supporting the emitter.10. The emitter assembly of wherein the protective sleeve is slidably mounted around the emitter. ...

Final Joint of Immersed Tunnel as well as Prefabrication Method and Installation Method

The present application discloses a final joint of an immersed tunnel, a prefabrication method and an installation method, wherein the final joint includes two end surfaces connected with installed adjacent tube sections; the two end surfaces are both tilted surfaces, so that the longitudinal profile of the final joint along an installation direction is of an inverted trapezoid structure; and the final joint further may be of a structure with a tube section I and a tube section II which are connected with each other. The final joint of the immersed tunnel is simple in structure, convenient to control and relatively high in precision, thereby reducing lots of open sea diving work and lowering a risk of installation quality defects; as prefabrication procedures are simple, the final joint may be prefabricated in a land factory and then transported to the site, thereby reducing influence of weather conditions on construction; a body structure of the final joint is prefabricated in the factory, and then the overall final joint is transported to the site for installation; water stop systems realize quick water stop, thus forming a dry construction environment; and therefore, the influence of weather and tidal current conditions on a project may be reduced, and a quality risk may be lowered. 1. A final joint of an immersed tunnel , comprising two end surfaces connected with installed adjacent tube sections; and the two end surfaces are both tilted surfaces , so that the longitudinal profile of the final joint along an installation direction is of an inverted trapezoid structure.2. The final joint of the immersed tunnel according to claim 1 , wherein the final joint comprises a tube section I and a tube section II connected with each other; and connection surfaces of the tube section I and the tube section II are tilted surfaces respectively connected with the installed adjacent tube sections claim 1 , so that the longitudinal profile of the final joint jointly formed by ...

HILIC / ANION-EXCHANGE / CATION-EXCHANGE MULTIMODAL MEDIA

The present invention provides an agglomerated multimodal chromatographic medium. the medium of the invention includes groups active in anion exchange, cation exchange and hydrophilic interaction chromatographic modalities. The invention provides methods of making these media and using them in separations of analytes. Also provided are separations devices incorporating the medium and systems incorporating these separations devices. 1. An agglomerated multimodal chromatographic medium with hydrophilic interaction , cation exchange and anion exchange properties , said medium being suitable for use as chromatographic packing and comprising:(a) component A comprising substrate particles functionalized with an ion exchange ligand comprising a negatively charged ion exchange group, and a hydrophilic ligand comprising a neutral polar group, wherein neither said ion exchange ligand nor said hydrophilic ligand contain more than 5 non-aromatic carbon atoms in series, and each of said ion exchange ligand and said hydrophilic ligand is bound to said substrate; and(b) component B comprising particles of a second substrate having positively charged external surfaces,wherein component A and component B are bound by electrostatic forces between said charged ion exchange ligand of component A and said charged external surfaces component B forming, in composite, an agglomerated medium of ion exchange particles.2. The agglomerated multimodal chromatographic medium of in which said polar group is a member selected from a protonated carboxylic acid claim 1 , an amide claim 1 , a urea claim 1 , an alcohol claim 1 , an ether claim 1 , and a combination thereof.3. The agglomerated multimodal chromatographic medium of in which said component B charged external surfaces comprise a member selected from a sulfonate claim 1 , a carboxylate claim 1 , a phosphate and a charged amine.4. The agglomerated multimodal chromatographic medium of claim 1 , wherein said component A substrate particles are ...

METHOD FOR EXTRACTING HIGH-PURITY ASARININ BY SUPERCRITICAL CARBON DIOXIDE EXTRACTION METHOD AND USE THEREOF

The invention discloses a method for extracting high-purity asarinin and use thereof. The method comprises: putting crude powder in an SFE-COdevice; under the conditions that an extraction kettle has a pressure of 30-40 Mpa and a temperature of 45-70° C., separating kettles I and II have a pressure of 5-10 Mpa, a temperature of 30-50° C. and the flow rate of COis 35-60 L/h, extracting for 60-240 min to obtain total volatile oil of ; standing the total volatile oil of for 24-72 h at a low temperature, and carrying out suction filtration under reduced pressure to obtain crude asarinin; and re-crystallizing the crude asarinin in absolute ethanol twice to obtain pure asarinin. It is found for the first time that asarinin has a good cough-relieving activity and thus can be used in preparing medicines for treating various types of coughs. 1. A method for extracting high-purity asarinin by an SFE-COmethod , characterized in that: the method comprises the operating steps below:{'i': asarum', 'asarum, '(1) washing roots and/or rootstocks of , airing and smashing to obtain crude powder;'}{'i': asarum', 'asarum;, 'sub': 2', '2, '(2) putting the crude powder in an extraction kettle of an SFE-COdevice and sealing; respectively heating the extraction kettle and separating kettles, opening a valve of the extraction kettle when the extraction kettle reaches a temperature of 45-70° C., and the separating kettles I and II reach a temperature of 30-50° C., opening an exhaust valve to empty air when a pressure in the extraction kettle is equal to that of a storage tank, pressurizing a system by a high-pressure pump, and controlling a flow rate of COto 35-60 L/h to start cycling extraction when the extraction kettle reaches a pressure of 30-40 Mpa, and the separating kettles I and II reach a pressure of 5-10 Mpa; and extracting for 60-240 min to obtain total volatile oil of'}{'i': 'asarum', '(3) standing the total volatile oil of for 24-72 h at a low temperature of −20-4° C., and ...

FUSED TRICYCLIC PYRAZOLE DERIVATIVES USEFUL FOR FARNESOID X RECEPTORS

The present invention relates to compounds of Formula I, 3. The compound according to claim 1 , wherein Lis *—(CRR)—; *—(CRR)—C(O)—NR—; *—(CRR)—O—; *—(CRR)—NR—SO—; *—(CRR)—NR—C(O)—; *—(CRR)—C(O)—NR—(CRR)—; or *—(CRR)—NR—C(O)—NR—(CRR)-1; wherein “*” indicates the point of attachment of Lto N.4. The compound according to claim 1 , wherein Ris Calkyl; Chaloalkyl; Chydroxyalkyl; or halo-substituted Chydroxyalkyl.5. The compound according to claim 1 , wherein Ris cyclopropyl claim 1 , cyclobutyl claim 1 , cyclopentyl claim 1 , cyclohexyl; each of which is unsubstituted or substituted by 1-2 substituents independently represented by R; wherein Ris halo or hydroxyl.6. The compound according to claim 1 , wherein Ris tetrahydofuranyl claim 1 , tetrapyranyl claim 1 , N-methyl pyrazolyl claim 1 , thiazolyl or 1 claim 1 ,1-dioxidotetrahydrothiophen-3-yl.7. The compound according to claim 1 , wherein{'sup': 0', '6', '7', '4', '5', '4', '5', '4', '5', '4', '5', '4', '5, 'sub': 2', '2-3', '2, 'Ris phenyl optionally substituted with halo, —C(O)NRR; —S(O)—NRN; —C(O)O—(CRCR)NRR; —N(R)—C(O)O—R; —SOR; —NRRor —(CRR)—C(O)OR;'}{'sup': 4', '5', '6', '7', '6', '7, 'sub': '1-6', 'wherein R, R, R, Rand Rare independently hydrogen or Calkyl; alternatively Rand Rtogether with N may form morpholinyl.'}8. The compound according to claim 1 , wherein Ring B is phenyl optionally substituted with 1-2 halo; tetrahydropyranyl claim 1 , cyclopentyl claim 1 , cyclohexyl or thiazolyl.9. The compound according to claim 1 , wherein X is —(CRR)—; and Rand R claim 1 , are independently hydrogen or methyl.10. The compound according to claim 1 , wherein Ris hydrogen claim 1 , halo claim 1 , sec-butyl claim 1 , vinyl or cyclopropyl11. The compound according to selected from:2-(1-{8-chloro-1-methyl-1H,4H-chromeno[4,3-c]pyrazol-3-yl}-N-[(3-fluorophenyl)methyl]formamido)-N-(cyclopropylmethyl)acetamide;2-(1-{8-chloro-1-methyl-1H,4H-chromeno[4,3-c]pyrazol-3-yl}-N-[(3-fluorophenyl)methyl]formamido)-N-(3,3,3- ...

Use of asarinin in preparation of medicines for treating various coughs method and use thereof

The invention discloses a use of asarinin in preparation of medicines for treating various coughs. The asarinin is used for preparing medicines for treating various coughs separately or in combination with other medicines. The asarinin can be extracted by an SFE-CO2 method. The asarinin and usable drug carriers or excipients are made into various formulations. And the formulations are granules, tablets, capsules, soft capsules, pills, dripping pills, ointments, syrups, injection, oral liquid, tinctures, sustained-releasing drugs, controlled release drugs or targeting preparations.

ASARUM TOTAL POLYSACCHARIDES EXTRACT HAVING ANTITUSSIVE ACTIVITY AND EXTRACTION METHOD AND USE THEREOF

The present invention discloses an total polysaccharide extract with antitussive activity, an extraction method thereof and an application in the preparation of a medicine for preventing and treating coughs. The present invention proves that the total polysaccharide extract has a significant effect of suppressing cough for the first time through a large number of pharmacodynamic tests, has the therapeutic effect approximate to codeine, has the effect of prolonging the cough latent period better than codeine, and also finds that the total polysaccharide extract has the effects of reducing the cough sensitivity and suppressing the airway inflammation for the first time, has excellent preventive and therapeutic effects on various types of coughs, and can be used for preparing the medicines for preventing and treating cough-related diseases. 1Asarum. An application comprising total polysaccharide extract in the preparation of a medicine for preventing and treating coughs.2. The application according to claim 1 , wherein the cough is chronic cough.3Asarum. The application according to claim 1 , wherein the percentage content of polysaccharide in the total polysaccharide extract is 60 wt % to 80 wt %.4Asarum. A pharmaceutical composition for preventing and treating coughs claim 1 , wherein the active ingredients comprise total polysaccharide extract.5. The pharmaceutical composition for preventing and treating coughs according to claim 4 , wherein the formulations of the pharmaceutical composition are granules claim 4 , tablets claim 4 , capsules claim 4 , pills claim 4 , dripping pills claim 4 , effervescent tablets claim 4 , ointments claim 4 , syrups claim 4 , injections claim 4 , oral liquid claim 4 , mixtures claim 4 , tinctures claim 4 , sustained-release preparations claim 4 , controlled-release preparations or targeting preparations.6Asarum. The pharmaceutical composition for preventing and treating coughs according to claim 4 , wherein the percentage content of ...

Compositions and methods for modulating farnesoid x receptors

The present invention relates to compounds of Formula I, a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesoid X receptors (FXR).