Oxime substituted 1-(3-(heteroaryl)phenyl)-benzimidazole compounds having GABA activity
Номер патента: NZ503435A
Опубликовано: 21-12-2001
Автор(ы): Frank Watjen, Lene Teuber, Yasuyuki Ichimaru, Yoshimasa Fukudu
Принадлежит: Neurosearch AS
Опубликовано: 21-12-2001
Автор(ы): Frank Watjen, Lene Teuber, Yasuyuki Ichimaru, Yoshimasa Fukudu
Принадлежит: Neurosearch AS
Реферат: A benzimidazole compound has the formula (I) or a pharmaceutically acceptable salt thereof wherein: R11 is a 5 or 6 membered monocyclic heteroaryl group containing at least one nitrogen or an N-oxide thereof; one of R6 and R7 is H and the other is CR'=NOR"; R' is H, alkyl, alkenyl, alkynyl or phenyl; R" is alkyl, alkenyl, alkynyl or phenyl substituted with one or more hydroxy groups. A pharmaceutical composition thereof is useful for treating anxiety, sleep or memory disorders or epilepsy or other convulsive disorders.
Dihydropyridine compounds having unique pharmacological effects, and the process for producing them
Номер патента: CA1300157C. Автор: Takashi Fujikura,Masaharu Asano,Yasuo Isomura,Yuzo Matsumoto,Toichi Takenaka,Noriki Ito. Владелец: Yamanouchi Pharmaceutical Co Ltd. Дата публикации: 1992-05-05.