Process for preparing heterocyclic methanone compounds and aza-bicyclo intermediates thereof
Номер патента: EP4240740A1
Опубликовано: 13-09-2023
Автор(ы): Christian GRUGEL
Принадлежит: Actinogen Medical Ltd
Опубликовано: 13-09-2023
Автор(ы): Christian GRUGEL
Принадлежит: Actinogen Medical Ltd
Реферат: The present disclosure relates to a process for synthesis of heterocyclic methanone compounds, and in particular 3'-substituted, 3-hydroxyl-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1h-pyrazol-4-yl)-thiophen-3-yl]-methanone compounds, and aza-bicyclo intermediates thereof. In particular, the present disclosure also relates to a process for the synthesis of Xanamem. The present disclosure also relates to a process for the synthesis of optionally protected aza-bicyclo intermediate compounds. The present disclosure also relates to 3'-substituted, 3-hydroxyl-(8-aza-bicyclo[3.2.1]oct-8-yl)-[5-(1h-pyrazol-4-yl)-thiophen-3-yl]-methanone compounds and aza-bicyclo intermediate compounds thereof.
Process for preparing heterocyclic methanone compounds and aza-bicyclo intermediates thereof
Номер патента: AU2021374232A9. Автор: Tobias Wedel,Christian GRUGEL. Владелец: Actinogen Medical Ltd. Дата публикации: 2024-09-26.