(1,3)-Diaza-(2)-phospha-cyclohexane derivs. - with pharmacodynamic and germicidal activity, prepd. by reacting phosphordiamide cpds. with malonyl chloride derivs.
Номер патента: DE2600665A1
Опубликовано: 21-07-1977
Автор(ы): H J Prof Dr Roth
Принадлежит: Individual
Опубликовано: 21-07-1977
Автор(ы): H J Prof Dr Roth
Принадлежит: Individual
Реферат: New 1,3-diaza-2-phospha-cyclohexane derivs. are of formula (I) (where R1 is alkyl, cycloalkyl or aryl; and R2, R3 R4 and R5 are H, alkyl, cycloalkyl, alkenyl or aryl). (I) are phosphorous analogues of barbituric acids. Specific cpds. (I) include 1,3-di-n-propyl-2,4,6-trioxo-2-ethoxy 1,3-diaza-2-phospha-cyclohexane. In an example, this is prepd. by reacting malonyl chloride with phosphoric acid ethyl ester bis-n-propyl-amide in Et2O.
2,3'-anhydro-2'-deoxy-5-fluorouridine derivatives with cytotoxic activity, a manufacturing process and application
Номер патента: US20160024133A1. Автор: Lech Celewicz,Karol KACPRZAK,Marta LEWANDOWSKA,Piotr RUSZKOWSKI. Владелец: Uniwersytet Im Adam Mickiewicza w Poznaniu. Дата публикации: 2016-01-28.