WATER-INSOLUBLE PREPARATIONS OF PEPTIDE MATERIALS, THEIR PRODUCTION AND THEIR USE

There are disclosed water-insoluble proteinic preparations in which a protein or polypeptide is bound to a copolymer, which preparations are useful for binding enzymes in order to carry out enzyme-catalyzable reactions. These preparations comprise a peptide material bound to a crosslinked copolymer comprising the following copolymerized units: (A) about 0.1 to 30 wt. % of at least one .alpha.,.beta.monoolefinically unsaturated dicarboxylic acid anhydride having about 4 to 9 carbon atoms; (B) about 35 to 90 wt. % of at least one di- and/or poly(meth)acrylate of a diol and/or polyol as hereinafter defined; and (C) about 5 to 60 wt. % of at least one hydrophilic monomer, the copolymer having a bulk volume of 1.4 to 30 ml/g and a specific surface area of about 1 to 500 m2/g, and containing, after saponification of the anhydride groups, about 0.01 to 14 milliequivalents of acid per gram.