Reduced pressure wound closure systems

A reduced-pressure, wound closure system (104) is presented that generates a closing force on a surface wound (111) and optionally provides reduced pressure to a body cavity (110) or tissue site (106). A sealed contracting member (188), when placed under reduced pressure, generates the closing force. One illustrative system (104) includes a first attachment member (172) and a second attachment member (184), a sealed contracting member (188) coupled to the first attachment member (172) and the second attachment member (184), and wherein the closing force is generated between the first attachment member (172) and the second attachment member (184) when reduced pressure is supplied to the sealed contracting member (188). Other systems and methods are presented.