Dimeric peptides having a stimulatory effect on haemopoiesis and a process for their preparation.

Dimeric peptides having a stimulatory effect on haemopoiesis and a process for their preparation

Номер патента: CA1337407C
Опубликовано: 24-10-1995
Автор(ы): Ole Didrik Laerum
Принадлежит: Nycomed AS

Реферат: Novel peptides are described consisting of dimeric peptide chains linked by a disulphide bridge. The dimers have a stimulatory effect on haemopoiesis, by contrast with the inhibitory effect of the monomer analogues.

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Pharmaceutical formulations containing 3-(4-cinnamyl-l-piperazinyl) amino derivatives of 3-formylrifamycin SV and 3-formylrifamycin S and a process of their preparation

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Aza-tanshinone derivatives, process for their preparation and their use in therapy

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Pharmaceutical formulations and processes for their preparation

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Pharmaceutical formulations and processes for their preparation

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Crystalline forms of 1-[(3r)-6,8-difluoro-3,4-dihydro-2h-1-benzopyran-3-yl]-1,3-dihydro-5- [2-[(phenylmethyl)amino]ethyl] -2h-imidazole-2-thione and processes for their preparations

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Aryl-substituted propanolamine derivatives, their preparation, pharmaceuticals comprising them, and their use

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Combinations with statin and aryl-substituted propanolamine derivatives, their preparation, pharmaceuticals comprising them, and their use

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Derivatives of aryl carboxylic acids, methods for their preparing, pharmaceutical composition based on thereof, methods for treatment and prophylaxis of different diseases, intermediate compounds and methods for their preparing

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Pentafluorosulfanylbenzoylguanidines, method for their preparing, their using and medicinal agent

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New polymorphic forms of minocycline base and processes for their preparation

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Substituted beta-carbolines, method for their preparing

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Crystals of taxane derivatives and method for their preparing

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Perfluorinated cycle-containing tertiary amines as base of gas-transferring emulsions (variants) and method for their preparing

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Amide derivatives of carboxylic acid, method for their preparing and pharmaceutical compositions based on thereof

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Substituted pyridines and pyrimidines processes for their preparation and their use as pesticides and fungicides

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Substituted quinoxalyl-imidazolidine-2,4-diones, processes for their preparation, their use as medicaments and pharmaceutical preparations

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INDOLE-2-CARBOXAMIDES AS INHIBITORS OF FACTOR Xa AND/OR VIIa, MEDICINAL AGENT BASED ON THEREOF AND METHOD FOR THEIR PREPARING

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PYRROLO[2,3-b] PYRIDINE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION COMPRISING THEM

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Solid forms of dabigatran etexilate mesylate and processes for their preparation

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3-Dicyclohexylaminosydnone imines, process for their¹preparation and their use

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Polyisoprenylbenzophenone derivatives, processes for their preparation and use thereof

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Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments

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Substituted-4-amino-3-pyridinols, a process for their preparation and their use as medicaments

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Substituted tetrahydroisoquinoline compounds, their preparation and use in medicaments

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Substituted tetrahydroisoquinoline compounds, their preparation and use in medicaments

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Substituted tetrahydroisoquinoline compound, their preparation and use in medicaments

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A process to prepare pioglitazone via several intermediates.

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Coniosetin and derivatives thereof, process for the preparation and the use thereof

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Palonosetron free base and process for its preparation

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Substituted 10-membered ring lactones, processes for their¹preparation use thereof

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Palonosetron free base and process for its preparation

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Palonosetron free base and process for its preparation

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New piperidine compounds, a process for their preparation and pharmaceutical compositions containing them

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Derivatives of phenylglycine, method for their preparing, intermediate compounds, pharmaceutical composition and method for treatment

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Novel thiophene-2-carboxylic acid derivatives and process for their production

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Novel thiophene-2-carboxylic acid derivatives and process for their production

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Derivatives of quinuclidineamide, method for their preparing and their using, pharmaceutical composition, combined product and method for inhibition of muscarinic receptors

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Substituted hexahydropyrazino [1,2-a] pyrimidine-4,7-dione derivatives, process for their preparation and their use as medicaments

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(1S,2S,3R,5R)-2-[(3S)-2-halo-3-hydroxy-1-alken(ynyl)]-3-trialkylsilyloxy-7,7-(2,2-dimethyl-trimethylenedioxy)bicyclo[3.3.0]octane compounds and processes for their preparation

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Analogs of 1,2,4-triazolophthalazines as anticancer drugs and a process for their preparation

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Derivatives of chroman and methods for their preparing

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Analogs of prostacyclin, intermediate products thereof, processes for their preparation and their use as medicaments

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Cephalosporin derivatives: processes for preparation, intermediates and pharmaceutical compositions

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Processes for the preparation of paliperidone and pharmaceutically acceptable salts thereof and intermediates for use in the processes

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Cyanoacetyl compounds, method for their preparing and their using (variants), composition and method for control of parasites

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Novel derivatives of swainsonine, processes for their preparation, and their use as therapeutic agents

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Novel substituted tetracyclic imidazole derivatives, processes for their preparation, pharmaceutical compositions comprising them and their use as a medicine

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Rifaximine polymorphous forms, methods for their preparing and their using in medicinal preparations

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Conjugates of 4-benzylaminoquinolines with bile acid and their heteroanalogs, method for their preparing and drugs based on these compounds

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Benzamide derivatives, processes for their preparation, and their pharmaceutical use

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Novel purpurone-type alkaloids, process for their preparation, and their usage as medications

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9a-n-[n'-(phenylsulfonyl)carbamoyl]-derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerythromycin a and 5-desosaminyl-9-deoxo-9-dihydro-9a-aza-9a-homoerythronolide a, method for their preparing and pharmaceutical composition based on thereof

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Substituted 6-phenyldihydro-3(2h)-pyridazinones, a process for their preparation and pharmaceutical preparations containing these compounds

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Novel isothiazolamides, processes for their preparation and their use as fungicides

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Optically active, heteroaromatic .beta.-hydroxy esters, processes for their preparation from .beta.-keto esters and processes for the preparation of these .beta.-keto esters

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Pyrrolic derivatives, processes for preparing the same and their uses as a drug

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Substituted dihydropteridin-6-one derivatives, process for their preparation and their use as kinase inhibitors

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Pyrrolic derivatives, processes for preparing the same and their uses as a drug

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Endiandric acid H and its derivatives, process for their preparation and use thereof

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Substituted dihydropteridin-6-one derivatives, process for their preparation and their use as kinase inhibitors

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Pyrrolo[4,3,2-de]quinolin-8-amine compounds and methods of their preparation and use

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Derivatives of quinoline, method for their preparing and their using, medicinal agent and method for inhibition of tumor cell proliferation

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Monoclinic CeTi2O6 thin film and a sol-gel process for the preparation thereof

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a complex comprising a sheet containing at least one textile reinforcement layer and a thickening material, process for preparing said complex and composite material containing a resin matrix and said complex

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Power semiconductor device, particularly a thyristor and a gridistor, and process for its production

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ARTICLES COMPRISING FIBRES AND/OR FIBRIDS, FIBRES AND FIBRIDS AND PROCESS FOR OBTAINING THEM

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Process for Producing Low-Sulfur Gas Oil Fraction, and Low-Sulfur Gas Oil

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SWITCH SYSTEM HAVING A BUTTON TRAVEL LIMIT FEATURE

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WAFER LEVEL PACKAGE HAVING A PRESSURE SENSOR AND FABRICATION METHOD THEREOF

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Textured filament yarns and a process and apparatus for their manufacture

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New tripeptides with effects on the central nervous system and a process for preparing the same

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ANODE-SUPPORTED SOLID OXIDE FUEL CELL COMPRISING A NANOPOROUS LAYER HAVING A PORE GRADIENT STRUCTURE, AND A PRODUCTION METHOD THEREFOR

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SMALL MOLECULE INHIBITORS OF BACTERIAL MOTILITY AND A HIGH THROUGHPUT SCREENING ASSAY FOR THEIR IDENTIFICATION

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Twist lock assembly comprising a base plate having a planar portion secured to a spacer, a rotatable locking pin and a handle rigidly connected through the spacer to the locking pin, the handle and planar portion being coplanar

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A New or Improved Electrode for Galvanic Cells and a Method or Process for Producing same.

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Process for the manufacture of granulates containing potassium chloride and magnesium sulphate hydrate

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Method of Fabricating A Semicoductor Device Having A Lateral Double Diffused Mosfet Transistor with a Lightly Doped Source and a CMOS Transistor

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POLY-TRIMETHYLENE TEREPHTHALATE SOLID CORE FIBRILLATION-RESISTANT FILAMENT HAVING A SUBSTANTIALLY TRIANGULAR CROSS SECTION, A SPINNERET FOR PRODUCING THE FILAMENT, AND A CARPET MADE THEREFROM

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POLY-TRIMETHYLENE TEREPHTHALATE SOLID CORE FIBRILLATION-RESISTANT FILAMENT HAVING A SUBSTANTIALLY TRIANGULAR CROSS SECTION, A SPINNERET FOR PRODUCING THE FILAMENT, AND A CARPET MADE THEREFROM

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BIPOLAR TRANSISTOR WITH A COLLECTOR HAVING A PROTECTED OUTER EDGE PORTION FOR REDUCED BASED-COLLECTOR JUNCTION CAPACITANCE AND A METHOD OF FORMING THE TRANSISTOR

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Polymer particles having a plurality of pores therein, a method for producing the same, and a resin composition containing the polymer particles

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A general-purpose printed circuit board having a mounting pad capable of mounting various kinds of semiconductor packages and a semiconductor memory module using the same

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METHOD OF MANUFACTURING CRYSTALLINE ELEMENTS OF PIEZOELECTRIC RESONATORS 1 2 process; increased consumption of crystalline raw materials; lack of accuracy due to rapid wear of the ultrasonic machine tool. In the manufacture of crystalline elements of the piezoelectric resonators by the proposed method, these disadvantages are eliminated. 10 FIG. 1, a, b, c, shows the crystalline elements of the U-shaped, H-shaped and zigzag forms; in fig. 2 - blank with slotted grooves. The proposed method consists in that 15 not individual bars are cut from the original single crystal, but blanks having a thickness S equal to the thickness of the crystal element and a width I equal to its length (Fig. 2). The length of the workpiece must be equal to the sum of the widths of several piezoelectric elements and allowances corresponding to the required number of cuts with diamond cutting discs with an internal cutting edge. Each workpiece / is glued together with a 25 glass substrate 2 onto the holder 3 of the cutting machine with cutting wheels having an inner cutting edge. After cutting off the test piece from the workpiece, 30 to correct the cutting angle, the caliper 20

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Water quality deodorant and method for preparing the same mainly including a powder having a particle size ranging from 0.4 to 10 [mu]m and a porous structure

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Poly-trimethylene terephthalate solid core fibrillation-resistant filament having a substantially triangular cross section, a spinneret for producing the filament, and a carpet made therefrom

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Insecticide electric apparatus having a body with an upper portion of a semi-circular outline and a wide front opening

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AUTONOMOUS MOVABLE VEHICLE HAVING A FILLABLE CONTAINER AND AN ASSEMBLY INCLUDING THE AUTONOMOUS MOVABLE VEHICLE AND A FILLING STATION

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1,2-dihydropyridine compounds, method for their preparing and their using

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Low hygroscopic aripiprazole drug substance and processes for the preparation thereof

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Semiconductor Device Comprising Through Hole Vias Having a Stress Relaxation Mechanism

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Scanned Beam Display Having a Redirected Exit Cone

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PROCESS FOR MANUFACTURING STEEL BLANKS

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Process For Recovering Hydrogen And Carbon Dioxide From A Syngas Stream

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Process for Preparing Quinoxaline Derivatives

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PROCESS FOR PRODUCING TEREPHTHALIC ACID

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PROCESS FOR PURIFYING TEREPHTHALIC ACID

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PROCESS FOR PREPARING TRI-N-PROPYLAMINE (TPA)

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Isoquinoline compounds, intermediate compounds, methods for their preparing and using

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New aluminium salts of substituted salicylic acids, and processes for their preparation

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WIPES HAVING A NON-HOMOGENEOUS STRUCTURE

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GRAPHENE PROCESSING FOR DEVICE AND SENSOR APPLICATIONS

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WIPES HAVING A NON-HOMOGENEOUS STRUCTURE

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POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING

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Rinsable dyes and methods for their preparation

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