Methods and devices for microfluidic point-of-care immunoassays
Опубликовано: 01-04-2009
Автор(ы): C. Frederick Battrell, Denise Maxine Hoekstra, Jason Capodanno, John Clemmens, John Gerdes, John R. Williford, Stephen Mordue
Принадлежит: Micronics Inc
Реферат: Microf luidic methods and devices for heterogeneous binding and agglutination assays are disclosed, with improvements relating to mixing and to reagent and sample manipulation in systems designed for safe handling of clinical test samples. In operation, sample port (2), via microchannel (3), is used to introduce test sample into the reservoir of left bellows pump (4). Similarly, 'waste' port (9), via microchannel (10), is used to introduce and discard reagent solutions into and out of the fluid chambers of right bellows pump (8). Ports (2) and (9) extend through the device cover (14) and are continuous with the fluid chambers of bellows pumps (4) and (8). Microchannels (3) and (10) may be modified to include valves (not shown). Active reciprocal flow of fluid between the right and left reservoirs is conducted through assay chamber (5) via focusing apertures (6) and (7).
Methods and devices for microfluidic point-of-care immunoassays
Номер патента: AU2007265628A1. Автор: C. Frederick Battrell,John Gerdes,John R. Williford,Denise Maxine Hoekstra,Stephen Mordue,John Clemmens,Jason Capodanno. Владелец: Micronics Inc. Дата публикации: 2008-01-03.