Systems and methods for assessing a bacterial or viral status of a sample
Номер патента: EP4334474A2
Опубликовано: 13-03-2024
Автор(ы): Ljubomir BUTUROVIC, Roland Luethy, Timothy Sweeney
Принадлежит: Inflammatix Inc
Опубликовано: 13-03-2024
Автор(ы): Ljubomir BUTUROVIC, Roland Luethy, Timothy Sweeney
Принадлежит: Inflammatix Inc
Реферат: Systems and methods for determining infectious disease states are provided. An ensemble classifier is obtained using a training dataset including labels and attribute values for a plurality of genes including at least 20 genes selected from one or more of Table 1, Table 2, Table 8, and Table 9. For each of a plurality of random seeds, initial classifiers with pseudo-randomly assigned hyperparameters are binned and downsampled using evaluation scores obtained from one or more iterations of K-fold cross-validation. The ensemble classifier is formed from initial classifiers with the best score for each random seed. Infectious disease states are determined for a test subject by inputting attribute values for the plurality of genes to a trained ensemble classifier. Compositions and kits for determining infectious disease states, including amplification primers for the plurality of genes, are further provided.
Systems and methods for receiving sensor data for an operating manufacturing machine and producing an alert during manufacture of a part
Номер патента: US09977425B1. Автор: LI ZHANG,Adam Mccann,Brandon Good,Jacob Berlier. Владелец: General Electric Co. Дата публикации: 2018-05-22.