Efficient gene delivery tool with a wide therapeutic margin
Номер патента: CA3160625A1
Опубликовано: 24-06-2021
Автор(ы): Alexander Weng, Hardy MITDANK, Simko Sama
Принадлежит: FREIE UNIVERSITAET BERLIN
Опубликовано: 24-06-2021
Автор(ы): Alexander Weng, Hardy MITDANK, Simko Sama
Принадлежит: FREIE UNIVERSITAET BERLIN
Реферат: The present invention relates to novel saponins of formula (I), comprising acetyl residues on two of their sugar residues. These saponins are able to enhance the transfection efficiency to a high extent and show much less cytotoxic side effects than already known saponins.
Multivalent terpene-based bolaamphiphiles for gene delivery
Номер патента: EP4232015A1. Автор: Peter M. IOVINE,Gopi Nath VEMURI,Jake Hughes. Владелец: San Diego, University of. Дата публикации: 2023-08-30.