Dual optical grating slide structured illumination imaging
Опубликовано: 25-03-2020
Автор(ы): Aaron Liu, Danilo Condello, Gary Mark SKINNER, Geraint Wyn EVANS, Merek C. Siu, Peter Clarke Newman, Shaoping Lu, Simon Prince, Stanley S. Hong
Принадлежит: Illumina Cambridge Ltd, Illumina Inc
Реферат: The disclosure provides for structured illumination microscopy (SIM) imaging systems. In one set of implementations, a SIM imaging system may be implemented as a multi-arm SIM imaging system, whereby each arm of the system includes a light emitter and a beam splitter (e.g., a transmissive diffraction grating) having a specific, fixed orientation with respect to the system's optical axis. In a second set of implementations, a SIM imaging system may be implemented as a multiple beam splitter slide SIM imaging system, where one linear motion stage is mounted with multiple beam splitters having a corresponding, fixed orientation with respect to the system's optical axis. In a third set of implementations, a SIM imaging system may be implemented as a pattern angle spatial selection SIM imaging system, whereby a fixed two-dimensional diffraction grating is used in combination with a spatial filter wheel to project one-dimensional fringe patterns on a sample.
Dual optical grating slide structured illumination imaging
Номер патента: SG11201911647RA. Автор: Shaoping Lu,Geraint Evans,Stanley Hong,Merek SIU,Gary Skinner,Danilo Condello,Simon Prince,Peter Newman,Aaron Liu. Владелец: Illumina Inc. Дата публикации: 2020-01-30.