Modulated lysine variant species compositions and methods for producing and using the same
Номер патента: EP2836513A1
Опубликовано: 18-02-2015
Автор(ы): Chee Furng Wong, Christopher CHUMSAE, Kartik Subramanian, Mayda Perez Thiele, Xiaobei Zeng, Ying Jing, Zehra Kaymakcalan
Принадлежит: AbbVie Inc
Опубликовано: 18-02-2015
Автор(ы): Chee Furng Wong, Christopher CHUMSAE, Kartik Subramanian, Mayda Perez Thiele, Xiaobei Zeng, Ying Jing, Zehra Kaymakcalan
Принадлежит: AbbVie Inc
Реферат: The instant invention relates to modulated lysine variant species compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods, e.g., cell culture and/or protein purification methods, for producing such modulated Lysine compositions. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNFα is detrimental, are also provided.
Method for preparing recombinant protein from bacterium and composition containing the same
Номер патента: US20200207875A1. Автор: Hua Jiang,Huili Lu,Jianwei Zhu,Yueqing XIE,Cedric CAGLIERO,Andrew Burnette,Manyu LUO. Владелец: Jecho Laboratories Inc. Дата публикации: 2020-07-02.