Methods for generating, evaluating, gene editing and cloning pluripotent stem cells comprising a lethal haplotype
Номер патента: CA3189774A1
Опубликовано: 27-01-2022
Автор(ы): David Kendall, Diego MORENO
Принадлежит: INGURAN LLC
Опубликовано: 27-01-2022
Автор(ы): David Kendall, Diego MORENO
Принадлежит: INGURAN LLC
Реферат: The invention includes a method of evaluating a bovine embryo by fertilizing an egg obtained from a first bovine heterozygote of a recessive lethal haplotype with sperm cells obtained from a second bovine heterozygote of the recessive lethal haplotype; producing the embryo from the fertilized egg, wherein the embryo is homozygous for the lethal haplotype; establishing a cell culture from the embryo; collecting a plurality of cultured cells; and obtaining omics data, comprising one or more features, from the plurality of cultured cells.
Panels of discrete microenvironments of cell cultures, methods for making such panels and use thereof
Номер патента: RU2718491C2. Автор: Маттиас ЛУТОЛЬФ,Адриан РАНГА. Владелец: Эколь Политекник Федераль Де Лозанн (Эпфл). Дата публикации: 2020-04-08.