NOVEL MALEIC ACID DERIVATIVE, PRODUCTION METHOD FOR SAME AND ANTI-CANCER COMPOSITION COMPRISING SAME
11-12-2014 дата публикации
Номер:
WO2014196784A1
Принадлежит: 재단법인 의약바이오컨버견스연구단, 한국화학연구원
Контакты:
Номер заявки: KR49-00-201433
Дата заявки: 03-06-2014
The present invention relates to a novel anti-cancer composition, and more specifically relates to a maleic acid derivative compound of chemical formula 1, to a production method for the compound, and to a pharmaceutical composition comprising the compound. The maleic acid derivative of the present invention suppresses the expression of AIMP2-DX2 and hence selectively suppresses the growth of cancer cell strains without acting on normal cells, and thus pharmaceutical compositions containing the maleic acid derivative of the present invention and pharmaceutically acceptable salts thereof as active ingredients can be used in order to prevent and treat cancer.[1][2]