CHARACTERIZATION OF DEFECTS OF THE PLATELET AGGREGATION.
Номер патента: ES2112310T3
Опубликовано: 01-04-1998
Автор(ы): Mark H Ginsberg
Принадлежит: Scripps Research Institute
Опубликовано: 01-04-1998
Автор(ы): Mark H Ginsberg
Принадлежит: Scripps Research Institute
Реферат: Methods are described for characterizing platelet aggregation defects. The defects are characterized as activation, ligand binding, or post-occupancy defects. In one embodiment of the invention a Cam variant of Glanzmann's thrombasthenia is characterized as having a ligand binding defect. In another embodiment, a patient with myelofibrosis is identified as having an activation defect. Rapid analysis are afforded using fluorescence-activated flow cytometry. Also, diagnostic kits are described which comprise antibodies suitable for characterizing the above defects.
Characterization of platelet aggregation disorders
Номер патента: CA2096230C. Автор: Mark H. Ginsberg. Владелец: Scripps Research Institute. Дата публикации: 2003-05-27.