RESORCINOL DERIVATIVE AS HSP90 INHIBITOR
28-07-2016 дата публикации
Номер:
WO2016116061A1
Автор: CHEN, Shuhui, DING, Charles Z., YAN, Xiaobing, HUANG, Wei, HU, Guoping, LI, Jian, ZHANG, Xiquan, YANG, Ling, XU, Hongjiang
Принадлежит: 南京明德新药研发股份有限公司
Контакты:
Номер заявки: CN16-07-201697
Дата заявки: 22-01-2016
The present invention relates to a compound represented by formula (I) of a resorcinol derivative as an HSP90 inhibitor or pharmaceutically accepted salts thereof. The compound in the present invention has the activity of inhibiting heat shock protein HSP90. Therefore, the compound in the present invention is used to treat proliferative diseases such as cancer and neurodegenerative diseases. The present invention further provides the compounds and preparation methods for pharmaceutical compositions comprising the compounds, a method for treating diseases, and pharmaceutical compositions comprising the compounds.[1][2]